花尻（木倉）瑠理（Hanajiri-Kikura Ruri)

最終出身大学院： 千葉大学大学院薬学研究科 修士課程修了
取得学位： 博士（薬学）（千葉大学）

兼職

千葉大学客員教授

賞

2009年 日本法中毒学会吉村賞受賞

研究分野

• 分析化学
• 薬物の安全性評価
• 法規制薬物

委員会・学会活動

原著論文

2023年

1. T. Shoda, G. Tsuji, M. Kawamura, T. Kurohara, T. Misawa, R. Kikura-Hanajiri, Y. Demizu: Structural analysis of an LSD Analog MiPLA: Insights from Rotamers in NMR Spectra. Drug test. Anal. accepted.
2. Tanaka, Rie; Kawamura, Maiko; Mizutani, Sakumi; Kikura-Hanajiri, Ruri: Characterization of novel LSD analog, 1-thiophenoyl LSD (1Tp-LSD) in sheet product Drug test. Anal., ahead of print, DOI: 10.1002/dta.3565 (2023).
3. Tanaka, Rie; Kikura-Hanajiri, Ruri: Identification of hexahydrocannabinol (HHC), dihydro-iso-tetrahydrocannabinol (dihydro-iso-THC) and hexahydrocannabiphorol (HHCP) in electronic cigarette cartridge products. Forensic Toxicology, ahead of print, https://doi.org/10.1007/s11419-023-00667-9 (2023).
4. Tanaka, Rie; Kawamura, Maiko; Mizutani, Sakumi; Kikura-Hanajiri, Ruri: Identification of LSD analogs, 1cP-AL-LAD, 1cP-MIPLA, 1V-LSD and LSZ in sheet products. Forensic Toxicology, 41, 294-303 (2023).
5. Tanaka, Rie; Mizutani, Sakumi; Kawamura, Maiko; Fuchino, Hiroyuki; Kawahara, Nobuo; Kikura-Hanajiri, Ruri: Determination of 11 cannabinoids in Cannabis sativa L. by liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF-MS). YAKUGAKU ZASSHI, 143, 411-418 (2023).

2022年

1. Morita, Izumi; Kiguchi, Yuki; Oyama, Hiroyuki; Yamaki, Kouya; Sakio, Nami; Kashiwabara, Keisuke; Kuroda, Yumi; Ito, Aya; Yokota, Asaka; Ikeda, Natsumi; Kikura-Hanajiri, Ruri; Ueda, Hiroshi; Numazawa, Satoshi; Yoshidade Takemi; Kobayashi, Norihiro: Derivatization-assisted immunoassays: application for group-specific detection of potent methamphetamine and amphetamine enantiomers. Anal. Methods (2022) 14:2745-2753.
2. Irie, Tomohiko; Yanase, Yuta; Demizu, Yosuke; Usami, Makoto; Kikura-Hanajiri, Ruri: Derivatives of methoxetamine and major methoxetamine metabolites potently block NMDA receptors. Journal of Pharmacological Sciences (2022) 150:233-243.
3. Tanaka, Rie; Kawamura, Maiko; Mizutani, Sakumi; Hakamatsuka, Takashi; Kikura-Hanajiri, Ruri: Identification of three arylcyclohexylamines (MXPr, MXiPr, and DMXE) in illegal products. YAKUGAKU ZASSHI (2022) 142:675-68.

2021年

1. Irie, Tomohiko; Yamazaki, Daijyu; Kikura-Hanajiri, Ruri: A potential of methoxpropamine to be a widespread recreational drug: it blocks NMDA receptors and inhibits NMDA receptor-mediated synaptic transmission in a brain preparation of mice. Forensic Toxicology (2021) 39:474-480.
2. Morita, Iaumi; Kiguchi, Yuki; Oyama, Hiroyuki; Takeuchi, Asuko; Tode, Chisato; Tanaka, Rie; Ogata, Jun; Kikura-Hanajiri, Ruri; Kobayashi, Norihiro: Derivatization-assisted enzyme-linked immunosorbent assay for identifying hallucinogenic mushrooms with enhanced sensitivity. Anal.Methods (2021) 13:3954.
3. Iida, Motoo; Kikura-Hanajiri, Ruri: NMR Study of the Discrimination of Enantiomers of Methamphetamine and Its Raw Materials Using Chiral Solvating Agents. Yakugaku Zasshi (2021) 141, 1041-1048.
4. Tanaka, Rie; Kawamura, Maiko; Hakamatsuka, Takashi; Kikura-Hanajiri, Ruri: Identification of six tryptamine derivatives as designer drugs in illegal products. Forensic Toxicol. 39: 248-258 (2021).

2020年

1. Tanaka, Rie; Kawamura, Maiko; Hakamatsuka, Takashi; Kikura-Hanajiri, Ruri: Identification of LSD Derivatives, 1cP-LSD, MIPLA and 1B-LSD in Illegal Products as Paper Sheet. Yakugaku Zasshi (2020) 140(11), 1405-1413.
2. Ogata, Jun; Kawamura, Maiko; Hakamatsuka, Takashi; Kikura-Hanajiri, Ruri: Discrimination of Kratom Products by an Improved PCR-RFLP Method. Yakugaku Zasshi (2020), 140(12), 1501-1508.
3. SamanWarnakulasuriya, Deirdre Cronin-Fenton, Jennifer Jinot, Farin Kamangar, Reza Malekzadeh, Nazir A Dar, Arash Etemadi, Paola Fortini, Deborah C Glass, Narges Khanjani, Ruri Kikura-Hanajiri, Nuria Malats, Akram Pourshams, Afarin Rahimi-Movaghar, David B Richardson, Vikash Sewram, Jennifer Girschik, Michelle C Turner, Eero Suonio, Yann Grosse, Lamia Benbrahim-Tallaa, Mahdi Sheikh, Bayan Hosseini, MengMeng Li, HeidiMattock, Kathryn Z Guyton, Mary K Schubauer-Berigan: Carcinogenicity of opium consumption. The Lancet Oncology (2020) 21(11): 1407-1408
4. Morita, Izumi; Oyama, Hiroyuki; Kiguchi, Yuki; Oguri, Akira; Fujimoto, Natsumi; Takeuchi, Atsuko; Tanaka, Rie; Ogata, Jun; Kikura-Hanajiri, Ruri; Kobayashi, Norihiko: Immunochemical monitoring of psilocybin and psilocin to identify hallucinogenic mushrooms. J. Pharm. Biomed. Anal., (2020) ,190, 113485.
5. Tanaka, Rie; Kawamura, Maiko; Hakamatsuka, Takashi; Kikura-Hanajiri, Ruri: Identification and Analysis of LSD Derivatives in Illegal Products as Paper Sheet. Yakugaku Zasshi (2020), 140(5), 739-750.
6. Irie, Tomohiko; Yamazaki, Daijyu; Kikura-Hanajiri, Ruri: F-phenibut (b-(4-Fluorophenyl)-GABA), a potent GABAB receptor agonist, activates an outward-rectifying K+ current and suppresses the generation of action potentials in mouse cerebellar Purkinje cells. Eur J Pharmacol., (2020), 884, 173437.
7. Kawahara, Genri; Nakayashiki, Masami S.; Maeda, Hideyuki; Kikura-Hanajiri, Ruri; Yoshida, Ken-ichi; Hayashi, Yukiko K.: Antagonists for serotonin receptors ameliorate rhabdomyolysis induced by 25D-NBOMe, a psychoactive designer drug. Forensic Toxicology (2020), 38(1), 122-128.

2019年

1. Kitajima, Mariko; Yamaguchi, Yasuka; Yanagisawa, Tomomi; Kogure, Noriyuki; Ogata, Jun; Kikura-Hanajiri, Ruri; Takayama, Hiromitsu: Biphenyl quinolizidine lactone alkaloids from "sinicuichi" (Heimia salicifolia). Tetrahydron, (2019),75, 3733-3739.
2. Mitsuoka, Toshinari; Hanamura, Kenji; Koganezawa, Noriko; Kikura-Hanajiri, Ruri; Sekino, Yuko; Shirao, Tomoaki: Assessment of NMDA receptor inhibition of phencyclidine analogues using a high-throughput drebrin immunocytochemical assay. Journal of Pharmacological and Toxicological Methods, (2019), 99, 106583.
3. Li, Ren-shi; Fukumori, Ryo; Takeda, Tomoki; Song, Yingxia; Morimoto, Satoshi; Kikura-Hanajiri, Ruri; Yamaguchi, Taku; Watanabe, Kazuhito; Aritake, Kousuke; Tanaka, Yoshitaka; the late Yamada, Hideyuki; Yamamoto, Tsuneyuki; Ishii, Yuji: Elevation of endocannabinoids in the brain by synthetic cannabinoid JWH-018: mechanism and effect on learning and memory. Sci. Rep. (2019), 9(1), 9621.

2018年

1. Kitajima, Mariko; Yanagisawa, Tomomi; Tsukahara, Mari; Yamaguchi, Yasuka; Kogure, Noriyuki; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Iida, Osamu; Sugimura, Yasushi; Kawahara, Nobuo; Takayama, Hiromitsu: Biphenyl ether and biphenyl quinolizidine lactone alkaloids from Heimia salicifolia. Tetrahedron (2018), 74(4), 441-452.
2. Maeda, Hideyuki; Nagashima, Erika; Hayashi, Yukiko K.; Kikura-Hanajiri, Ruri; Yoshida, Ken-ichi: MDMB-CHMICA induces thrashing behavior, bradycardia, and slow pressor response in a CB1- and CB2-receptor-dependent manner in conscious rats. Forensic Toxicology (2018), 36(2), 313-319.
3. Minakata, Kayoko; Hasegawa, Koutaro; Yamagishi, Itaru; Nozawa, Hideki; Kikura-Hanajiri, Ruri; Suzuki, Masako; Kitamoto, Takuya; Suzuki, Osamu; Watanabe, Kanako: Sensitive quantification of 5F-PB-22 and its three metabolites 5F-PB-22 3-carboxyindole, PB-22 N-5-hydroxypentyl and PB-22 N-pentanoic acid in authentic urine specimens obtained from four individuals by liquid chromatography-tandem mass spectrometry. Forensic Toxicol. (2018), 36(1), 151-159.

2017年

1. Malyshevskaya, Olga; Aritake, Kosuke; Kaushik, Mahesh K; Cherasse, Yoan; Urade, Yoshihiro; Uchiyama, Nahoko; Kikura-Hanajiri, Ruri: Natural (Δ9-THC) and synthetic (JWH-018) cannabinoids induce seizures by acting through the cannabinoid CB1 receptor. Scientific reports (2017), 7(1), 10516. doi: 10.1038/s41598-017-10447-2.
2. Fukuhara, Kiyoshi; Ohno Akiko; Kikura-Hanajiri Ruri: A Metabolic Study on the Biochemical Effects of Chiral Illegal Drugs in Rats Using 1H-NMR Spectroscopy. Yakugaku zasshi (2017), 137(9), 1147-1154.
3. Maeda, Hideyuki; Kikura-Hanajiri, Ruri; Kawamura, Maiko; Nagashima, Erika; Yoshida, Ken-ichi: AB-CHMINACA-induced sudden death from non-cardiogenic pulmonary edema. Clinical Toxicology (2017), Ahead of Print.
4. Hashimoto, Takashi; Hanajiri, Ruri; Yasuda, Nobuhiro; Nakamura, Yuki; Mizuno, Nobuhiro; Honda, Sadao; Hayakawa, Shinjiro; Nishiwaki, Yoshinori; Kimura, Shigeru: Single-crystal structure analysis of designer drugs circulating in the Japanese drug market by the synchrotron radiation X-ray diffraction. Powder Diffraction (2017), 32(2), 112-117.
5. Kawahara, Genri; Maeda, Hideyuki; Kikura-Hanajiri, Ruri; Yoshida, Ken-ichi; Hayashi, Yukiko K.: The psychoactive drug 25B-NBOMe recapitulates rhabdomyolysis in zebrafish larvae. Forensic Toxicology (2017), 35(2), 369-375.

2016年

1. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Hakamatsuka, Takashi: A phenethylamine derivative 2-(4-iodo-2,5-dimethoxyphenyl)-N-[(3,4-methylenedioxyphenyl)methyl]ethanamine (25I-NB34MD) and a piperazine derivative 1-(3,4-difluoromethylenedioxybenzyl)piperazine (DF-MDBP), newly detected in illicit products. Forensic Toxicology (2016), 34(1), 166-173.

2015年

1. Uchiyama Nahoko; Shimokawa Yoshihiko; Kikura-Hanajiri Ruri; Demizu Yosuke; Goda Yukihiro; Hakamatsuka Takashi: A synthetic cannabinoid FDU-NNEI, two 2H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products. Forensic toxicology (2015), 33(2), 244-259.
2. Toyo'oka, Toshimasa; Kikura-Hanajiri, Ruri: A reliable method for the separation and detection of synthetic cannabinoids by supercritical fluid chromatography with mass spectrometry, and its application to plant products. Chemical & Pharmaceutical Bulletin (2015), 63(10), 762-769.
3. Kudo, Keiko; Usumoto, Yosuke; Kikura-Hanajiri, Ruri; Sameshima, Naomi; Tsuji, Akiko; Ikeda, Noriaki: A fatal case of poisoning related to new cathinone designer drugs, 4-methoxy PV8, PV9, and 4-methoxy PV9, and a dissociative agent, diphenidine. Legal Medicine (2015), 17(5), 421-426.
4. Uchiyama, Nahoko; Asakawa, Kazuhiro; Kikura-Hanajiri, Ruri; Tsutsumi, Taizo; Hakamatsuka, Takashi: A new pyrazole-carboxamide type synthetic cannabinoid AB-CHFUPYCA [N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide] identified in illegal products. Forensic Toxicology (2015), 33(2), 367-373.
5. Piao, Ying-Shan; Hall, Frank Scott; Moriya, Yuki; Ito, Miki; Ohara, Arihisa; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Lesch, Klaus-Peter; Murphy, Dennis L.; Uhl, George R.; Sora, Ichiro: Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Behavioural Pharmacology (2015), 26(4), 345-352.
6. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Hakamatsuka, Takashi: Evaluation of an on-site drug-testing device for the detection of synthetic cannabinoids in illegal herbal products. Yakugaku Zasshi (2015), 135(3), 535-541.
7. Irie, Tomohiko; Kikura-Hanajiri, Ruri; Usami, Makoto; Uchiyama, Nahoko; Goda, Yukihiro; Sekino, Yuko: MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors. Neuropharmacology (2015), 95, 479-491.
8. Fuchigami, Yuki; Fu, Xunsing; Ikeda, Rie; Kawakami, Shigeru; Wada, Mitsuhiro; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro: Evaluation of the neurochemical effects of methoxetamine using brain microdialysis in mice. Forensic Toxicology (2015), 33(2), 374-379.
9. Uchiyama, Nahoko; Shimokawa, Yoshihiko; Kikura-Hanajiri, Ruri; Demizu, Yosuke; Goda, Yukihiro; Hakamatsuka, Takashi: A synthetic cannabinoid FDU-NNEI, two 2H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products. Forensic Toxicology (2015), 33(2), 244-259.

2014年

1. Uchiyama, Nahoko; Matsuda, Satoru; Kawamura, Maiko; Shimokawa, Yoshihiko; Kikura-Hanajiri, Ruri; Aritake, Kosuke; Urade, Yoshihiro; Goda, Yukihiro: Characterization of four new designer drugs, 5-chloro-NNEI, NNEI indazole analog, α-PHPP and α-POP, with 11 newly distributed designer drugs in illegal products. Forensic Science International (2014), 243, 1-13.
2. Uchiyama, Nahoko; Shimokawa, Yoshihiko; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Hakamatsuka, Takashi: Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products. Forensic Toxicology (2014), 32(2), 266-281.
3. Takayama, Takahiro; Suzuki, Mayu; Todoroki, Kenichiro; Inoue, Koichi; Min, Jun Zhe; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Toyo'oka, Toshimasa: UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome. Biomedical Chromatography (2014), 28(6), 831-838.
4. Uchiyama, Nahoko; Matsuda, Satoru; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Identification of two new-type designer drugs, piperazine derivative MT-45 (I-C6) and synthetic peptide Noopept (GVS-111), with synthetic cannabinoid A-834735, cathinone derivative 4-methoxy-α-PVP, and phenethylamine derivative 4-methylbuphedrine from illegal products. Forensic Toxicology (2014), 32(1), 9-18.
5. Kikura-Hanajiri, Ruri; Uchiyama, Nahoko; Kawamura, Maiko; Goda, Yukihiro: Changes in the prevalence of new psychoactive substances before and after the introduction of the generic scheduling of synthetic cannabinoids in Japan. Drug Testing and Analysis (2014), 6(7-8), 832-839.
6. Maruyama, Takuro; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Botanical origin of dietary supplements labeled as "Kwao Keur", a folk medicine from Thailand. Journal of Natural Medicines (2014), 68(1), 220-224.
7. Uchiyama, Nahoko; Shimokawa, Yoshihiko; Matsuda, Satoru; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Two new synthetic cannabinoids, AM-2201 benzimidazole analog (FUBIMINA) and (4-methylpiperazin-1-yl)(1-pentyl-1H-indol-3-yl)methanone (MEPIRAPIM), and three phenethylamine derivatives, 25H-NBOMe 3,4,5-trimethoxybenzyl analog, 25B-NBOMe, and 2C-N-NBOMe, identified in illegal products. Forensic Toxicology (2014), 32(1), 105-115.

2013年

1. Uchiyama, Nahoko; Matsuda, Satoru; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist AH-7921 identified in illegal products. Forensic Toxicology (2013), 31(2), 223-240.
2. Uchiyama, Nahoko; Matsuda, Satoru; Wakana, Daigo; Kikura-Hanajiri, Ruri; Goda, Yukihiro: New cannabimimetic indazole derivatives, N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA) and N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(4-fluorobenzyl)-1H-indazole-3-carboxamide (AB-FUBINACA) identified as designer drugs in illegal products. Forensic Toxicology (2013), 31(1), 93-100.
3. Takahashi, Kazunaga; Uchiyama, Nahoko; Fukiwake, Tomohide; Hasegawa, Takashi; Saijou, Masaaki; Motoki, Yuji; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Identification and quantitation of JWH-213, a cannabimimetic indole, as a designer drug in a herbal product. Forensic Toxicology (2013), 31(1), 145-150.
4. Kitajima, Mariko; Iwai, Masumi; Kogure, Noriyuki; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Takayama, Hiromitsu: Aspidosperma-aspidosperma-type bisindole alkaloids from Voacanga Africana. Tetrahedron (2013), 69(2), 796-801.
5. Kikura-Hanajiri R, Uchiyama N, Kawamura M, et al. Changes in the prevalence of synthetic cannabinoids and cathinone derivatives in Japan until early 2012. Forensic Toxicol. 2013; 31: 44-53.
6. Ogata, Jun; Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: DNA sequence analyses of blended herbal products including synthetic cannabinoids as designer drugs. Forensic Science International (2013), 227(1-3), 33-41.
7. Uchiyama, Nahoko; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: URB-754: A new class of designer drug and 12 synthetic cannabinoids detected in illegal products. Forensic Science International (2013), 227(1-3), 21-32.

2012年

1. Uchiyama, Nahoko; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Identification of two new-type synthetic cannabinoids, N-(1-adamantyl)-1-pentyl-1H-indole-3-carboxamide (APICA) and N-(1-adamantyl)-1-pentyl-1H-indazole-3-carboxamide (APINACA), and detection of five synthetic cannabinoids, AM-1220, AM-2233, AM-1241, CB-13 (CRA-13), and AM-1248, as designer drugs in illegal products. Forensic Toxicology (2012), 30(2), 114-125.
2. Inagaki, Shinsuke; Hirashima, Haruo; Taniguchi, Sayuri; Higashi, Tatsuya; Min, Jun Zhe; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Toyo'oka, Toshimasa: Rapid enantiomeric separation and simultaneous determination of phenethylamines by ultra high performance liquid chromatography with fluorescence and mass spectrometric detection: application to the analysis of illicit drugs distributed in the Japanese market and biological samples. Drug Testing and Analysis (2012), 4(12), 1001-1008.
3. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Matsumoto, Naomi; Huang, Zhi-Li; Goda, Yukihiro; Urade, Yoshihiro: Effects of synthetic cannabinoids on electroencephalogram power spectra in rats. Forensic Science International (2012), 215(1-3), 179-183.
4. Wada, Mitsuhiro; Yamahara, Kozue; Ikeda, Rie; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro: Simultaneous determination of N-benzylpiperazine and 1-(3-trifluoromethylphenyl)piperazine in rat plasma by HPLC-fluorescence detection and its application to monitoring of these drugs. Biomedical Chromatography (2012), 26(1), 21-25.

2011年

1. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Identification of a novel cannabimimetic phenylacetylindole, cannabipiperidiethanone, as a designer drug in a herbal product and its affinity for cannabinoid CB1 and CB2 receptors. Chemical & Pharmaceutical Bulletin (2011), 59(9), 1203-1205.
2. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Shoda, Takuji; Fukuhara, Kiyoshi; Goda, Yukihiro: Isomeric analysis of synthetic cannabinoids detected as designer drugs. Yakugaku Zasshi (2011), 131(7), 1141-1147.
3. Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Simple and rapid screening for methamphetamine and 3,4-methylene-dioxymethamphetamine (MDMA) and their metabolites in urine using direct analysis in real time (DART)-TOFMS. Yakugaku Zasshi (2011), 131(5), 827-833.
4. Takahashi, Kazunaga; Hasegawa, Takashi; Saijo, Masaaki; Nagata, Tomoko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Inspection of illegal drug in Chiba. Chiba-ken Eisei Kenkyusho Nenpo (2011), Volume Date2009, 58, 51-54.
5. Sogawa, Chiharu; Sogawa, Norio; Ohyama, Kazumi; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Sora, Ichiro; Kitayama, Shigeo: Methylone and monoamine transporters: correlation with toxicity. Current Neuropharmacology (2011), 9(1), 58-62.
6. Kitajima, Mariko; Iwai, Masumi; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Iida, Mitsuru; Yabushita, Hisatoshi; Takayama, Hiromitsu: Discovery of indole alkaloids with cannabinoid CB1 receptor antagonistic activity. Bioorganic & Medicinal Chemistry Letters (2011), 21(7), 1962-1964.
7. Wada, Mitsuhiro; Abe, Keisuke; Ikeda, Rie; Kikura-Hanajiri, Ruri; Kuroda, Naotaka; Nakashima, Kenichiro: HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection. Analytical and Bioanalytical Chemistry (2011), 400(2), 387-393.
8. Kikura-Hanajiri, Ruri; Kawamura, Maiko; Miyajima, Atsuko; Sunouchi, Momoko; Goda, Yukihiro: Chiral analyses of dextromethorphan/levomethorphan and their metabolites in rat and human samples using LC-MS/MS. Analytical and Bioanalytical Chemistry (2011), 400(1), 165-174.
9. Uchiyama, Nahoko; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Identification and quantitation of two cannabimimetic phenylacetylindoles JWH-251 and JWH-250, and four cannabimimetic naphthoylindoles JWH-081, JWH-015, JWH-200, and JWH-073 as designer drugs in illegal products. Forensic Toxicology (2011), 29(1), 25-37.

2010年

1. Takahashi, Mitsuko; Sakurai, Katsumi; Watabe, Kenjiro; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Establishment of LC/MS library for screening analysis on "non-approved or unauthorized pharmaceuticals" and "designated substances". Iyakuhin Iryo Kiki Regyuratori Saiensu (2010), 41(9), 742-749.
2. Abe, Yutaka; Yamaguchi, Miku; Mutsuga, Motoh; Hirahara, Yoshichika; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Kawamura, Yoko: Discrimination of plasticizers and screening of phthalates in polyvinyl chloride using DART-TOF/MS. Shokuhin Eiseigaku Zasshi (2010), 51(4), 160-169.
3. Min, Jun Zhe; Yamashita, Kazuhide; Toyo'oka, Toshimasa; Inagaki, Shinsuke; Higashi, Tatsuya; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Simultaneous and group determination methods for designated substances by HPLC with multi-channel electrochemical detection and their application to real samples. Biomedical Chromatography (2010), 24(12), 1287-1299.
4. Inagaki, Shinsuke; Taniguchi, Sayuri; Hirashima, Haruo; Higashi, Tatsuya; Min, Jun Zhe; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Toyo'oka, Toshimasa: HPLC enantioseparation of α,α-diphenyl-2-pyrrolidinemethanol and methylphenidate using a chiral fluorescent derivatization reagent and its application to the analysis of rat plasma. Journal of Separation Science (2010), 33(20), 3137-3143.
5. Kikuchi, Hiroyuki; Uchiyama, Nahoko; Ogata, Jun; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Chemical constituents and DNA sequence analysis of a psychotropic herbal product. Forensic Toxicology (2010), 28(2), 77-83.
6. Uchiyama, Nahoko; Miyazawa, Norimasa; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Analysis of newly distributed designer drugs detected in the products purchased in fiscal year 2008. Yakugaku Zasshi (2010), 130(2), 263-270.
7. Kikura-Hanajiri, Ruri; Kawamura, Maiko; Miyajima, Atsuko; Sunouchi, Momoko; Goda, Yukihiro Determination of a new designer drug, N-hydroxy-3,4-methylenedioxymethamphetamine and its metabolites in rats using ultra-performance liquid chromatography-tandem mass spectrometry. Forensic Science International (2010), 198(1-3), 62-69.
8. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Ogata, Jun; Goda, Yukihiro: Chemical analysis of synthetic cannabinoids as designer drugs in herbal products. Forensic Science International (2010), 198(1-3), 31-38.

2009年

1. Kikura-Hanajiri, Ruri; Maruyama, Takuro; Miyashita, Akinori; Goda, Yukihiro Chemical and DNA analyses for the products of a psychoactive plant, Voacanga africana. Yakugaku Zasshi (2009), 129(8), 975-982.
2. Min, Jun Zhe; Hatanaka, Suguru; Toyo'oka, Toshimasa; Inagaki, Shinsuke; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Rapid, sensitive and simultaneous determination of fluorescence-labeled designated substances controlled by the Pharmaceutical Affairs Law in Japan by ultra-performance liquid chromatography coupled with electrospray-ionization time-of-flight mass spectrometry. Analytical and Bioanalytical Chemistry (2009), 395(5), 1411-1422.
3. Matsushima, Yoshihiro; Shirota, Osamu; Kikura-Hanajiri, Ruri; Goda, Yukihiro; Eguchi, Fumio: Effects of Psilocybe argentipes on marble-burying behavior in mice. Bioscience, Biotechnology and Biochemistry (2009), 73(8), 1866-1868.
4. Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Simple and rapid screening for psychotropic natural products using direct analysis in real time (DART)-TOFMS. Yakugaku Zasshi (2009), 129(6), 719-725.
5. Kikura-Hanajiri, Ruri; Kawamura, Maiko; Maruyama, Takuro; Kitajima, Mariko; Takayama, Hiromitsu; Goda, Yukihiro: Simultaneous analysis of mitragynine, 7-hydroxymitragynine, and other alkaloids in the psychotropic plant "kratom" (Mitragyna speciosa) by LC-ESI-MS. Forensic Toxicology (2009), 27(2), 67-74.
6. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Kawahara, Nobuo; Goda, Yukihiro: Identification of a cannabimimetic indole as a designer drug in a herbal product. Forensic Toxicology (2009), 27(2), 61-66.
7. Maruyama, Takuro; Kawamura, Maiko; Kikura-Hanajiri, Ruri; Takayama, Hiromitsu; Goda, Yukihiro: The botanical origin of kratom (Mitragyna speciosa; Rubiaceae) available as abused drugs in the Japanese markets. Journal of Natural Medicines (2009), 63(3), 340-344.
8. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Kawahara, Nobuo; Haishima, Yuji; Goda, Yukihiro: Identification of a cannabinoid analog as a new type of designer drug in a herbal product. Chemical & Pharmaceutical Bulletin (2009), 57(4), 439-441.

2008年

1. Ogata, Jun; Kikura-Hanajiri, Ruri; Yoshimatsu, Kayo; Kiuchi, Fumiyuki; Goda, Yukihiro: Detection method for the ability of Hemp(Cannabis sativa I.) seed germination by the use of 2,3,5-triphenyl-2H-tetrazolium chloride (TTC). Yakugaku Zasshi (2008), 128(11), 1707-1711.
2. Uchiyama, Nahoko; Kikura-Hanajiri, Ruri; Kawahara, Nobuo; Goda, Yukihiro: Analysis of designer drugs detected in the products purchased in fiscal year 2006. Yakugaku Zasshi (2008), 128(10), 1499-1505.
3. Uchiyama, Nahoko; Saisho, Kazuhiro; Kikura-Hanajiri, Ruri; Haishima, Yuji; Goda, Yukihiro: Determination of a new type of phosphodiesterase-5 inhibitor, thioquinapiperifil, in a dietary supplement promoted for sexual enhancement. Chemical & Pharmaceutical Bulletin (2008), 56(9), 1331-1334.
4. Kawamura, Maiko; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Survey of current trends in the abuse of psychotropic plants using LC-MS. Nippon Shokuhin Kagaku Gakkaishi (2008), 15(2), 73-78.
5. Min, Jun Zhe; Shimizu, Yoshiha; Toyo'oka, Toshimasa; Inagaki, Shinsuke; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Simultaneous determination of 11 designated hallucinogenic phenethylamines by ultra-fast liquid chromatography with fluorescence detection. Journal of Chromatography B (2008), 873(2), 187-194.
6. Uchiyama, Nahoko; Kawamura, Maiko; Kamakura, Hiroyuki; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Analytical data of designated substances (Shitei-Yakubutsu) controlled by the pharmaceutical affairs law in Japan, part II: color test and TLC. Yakugaku Zasshi (2008), 128(6), 981-987.
7. Kikura-Hanajiri, Ruri; Kawamura, Maiko; Uchiyama, Nahoko; Ogata, Jun; Kamakura, Hiroyuki; Saisho, Kazuhiro; Goda, Yukihiro: Analytical data of designated substances (Shitei-Yakubutsu) controlled by the pharmaceutical affairs law in Japan, part I: GC-MS and LC-MS. Yakugaku Zasshi (2008), 128(6), 971-979.
8. Maruyama, Takuro; Kamakura, Hiroyuki; Kikura-Hanajiri, Ruri; Goda, Yukihiro: Authentication and ultra performance liquid chromatography (UPLC)/MS analysis of magic mint, Salvia divinorum and its related plants. Yakugaku Zasshi (2008), 128(1), 179-183.
9. Uchiyama, Nahoko; Kim, Ik Hwi; Kikura-Hanajiri, Ruri; Kawahara, Nobuo; Konishi, Tenji; Goda, Yukihiro: HPLC separation of naringin, neohesperidin and their C-2 epimers in commercial samples and herbal medicines. Journal of Pharmaceutical and Biomedical Analysis (2008), 46(5), 864-869.
10. Matsumoto, Teruki; Urano, Yasuteru; Makino, Yukiko; Kikura-Hanajiri, Ruri; Kawahara, Nobuo; Goda, Yukihiro; Nagano, Tetsuo: Evaluation of Characteristic Deuterium Distributions of Ephedrines and Methamphetamines by NMR Spectroscopy for Drug Profiling. Analytical Chemistry (2008), 80(4), 1176-1181.

2007年

1. Kikura-Hanajiri, Ruri; Kawamura, Maiko; Saisho, Kazuhiro; Kodama, Yukio; Goda, Yukihiro: The disposition into hair of new designer drugs; methylone, MBDB and methcathinone. Journal of Chromatography B (2007), 855(2), 121-126.
2. Sugiyama, Emiko; Kaniwa, Nahoko; Kim, Su-Ryang; Kikura-Hanajiri, Ruri; Hasegawa, Ryuichi; Maekawa, Keiko; Saito, Yoshiro; Ozawa, Shogo; Sawada, Jun-ichi; Kamatani, Naoyuki; Furuse, Junji;, Ishii, Hiroshi; Yoshida, Teruhiko; Ueno, Hideki; Okusaka, Takuji; Saijo, Nagahiro: Pharmacokinetics of gemcitabine in Japanese cancer patients: the impact of a cytidine deaminase polymorphism. Journal of Clinical Oncology (2007), 25(1), 32-42.

2006年

1. Matsumoto, Teruki; Kikura-Hanajiri, Ruri; Kamakura, Hiroyuki; Kawahara, Nobuo; Goda, Yukihiro: Identification of N-methyl-4-(3,4-methylenedioxyphenyl)butan-2-amine, distributed as MBDB. Journal of Health Science (2006), 52(6), 805-810.

2005年

1. Kikura-Hanajiri, Ruri; Hayashi, Midori; Saisho, Kazuhiro; Goda, Yukihiro: Simultaneous determination of nineteen hallucinogenic tryptamines/β-carbolines and phenethylamines using gas chromatography-mass spectrometry and liquid chromatography-electrospray ionisation-mass spectrometry. Journal of Chromatography B (2005), 825(1), 29-37.
2. Yonemori, Kan; Ueno, Hideki; Okusaka, Takuji; Yamamoto, Noboru; Ikeda, Masafumi; Saijo, Nagahiro; Yoshida, Teruhiko; Ishii, Hiroshi; Furuse, Junji; Sugiyama, Emiko; Kim, Su-Ryang; Kikura-Hanajiri, Ruri; Hasegawa, Ryuichi; Saito, Yoshiro; Ozawa, Shogo; Kaniwa, Nahoko; Sawada, Jun-ichi: Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin. Clinical Cancer Research (2005), 11(7), 2620-2624.

2004年

1. Kaddoumi, Amal; Kikura-Hanajiri, Ruri; Nakashima, Kenichiro: High-performance liquid chromatography with fluorescence detection for the simultaneous determination of 3,4-methylenedioxymethamphetamine, methamphetamine and their metabolites in human hair using DIB-Cl as a label. Biomedical Chromatography (2004), 18(3), 202-204.

2003年

1. Kikura-Hanajiri, Ruri; Kaniwa, Nahoko; Ishibashi, Mumio; Makino, Yukiko; Kojima, Shigeo: Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric analysis of opiates and metabolites in rat urine after inhalation of opium. Journal of Chromatography B (2003), 789(1), 139-150.

2002年

1. Kikura-Hanajiri, Ruri; Martin, R. Scott; Lunte, Susan M.: Indirect Measurement of Nitric Oxide Production by Monitoring Nitrate and Nitrite Using Microchip Electrophoresis with Electrochemical Detection. Analytical Chemistry (2002), 74(24), 6370-6377.
2. Sakamoto, Tomoaki; Hanajiri, Ruri; Ishibashi, Mumio; Kojima, Shigeo: Study on the reference spectra of the Japanese Pharmacopoeia III. Iyakuhin Kenkyu (2002), 33(7), 462-476.

総説・単行本等

総説等

1. 花尻（木倉）瑠理：危険ドラッグと合成カンナビノイド．Clinical Neuroscience, (2020), 38(8), 1033-1036.
2. 花尻（木倉）瑠理：危険ドラッグによる健康被害を防ぐ分析化学．ぶんせき(2018), 10, 445-449.
3. 花尻（木倉）瑠理：危険ドラッグの法規制と流通実態変化．日本薬理学雑誌(2017), 150(3), 129-134.
4. 内山奈穂子，花尻（木倉）瑠理：危険ドラッグと合成カンナビノイド．ファルマシア(2016)，52(9), 855-859.
5. 花尻（木倉）瑠理：危険ドラッグ流通実態調査における質量分析の役割．J. Mass Spectrom. Soc. Jpn. (2016), 64(4), 139-142.
6. 花尻（木倉）瑠理：危険ドラッグの法規制と流通実態変化．朝日メディカル(2016), 45(6), 32-33.
7. 花尻（木倉）瑠理：危険ドラッグの流通実態の変化．犯罪学雑誌(2016), 82(3), 1-5.
8. 田中理恵，河村麻衣子，内山奈穂子，瀬川勝智，中野達也，斎藤嘉朗，緒方潤，最所和宏，花尻（木倉）瑠理*，袴塚高志：国立衛研違法ドラッグデータ閲覧システムについて．国立医薬品食品衛生研究所報告(2016), No.134, 73-78.
9. 花尻（木倉）瑠理：「危険ドラッグ」とは，その検出事例の変遷．医薬ジャーナル(2016)，52(2), 57-60．
10. 花尻（木倉）瑠理：危険ドラッグの流通実態の把握と流通予測．公衆衛生(2015)，79(4), 255-258.
11. 花尻（木倉）瑠理：海外の脱法ドラッグ事情と日本における流通実態．警察学論集(2014)，67(12), 129-148.
12. 花尻（木倉）瑠理：危険ドラッグの規制と流通実態について．薬剤学(2015)，75(2), 121-127.
13. 花尻（木倉）瑠理：いわゆる“脱法ドラッグ（脱法ハーブ）”による健康被害を防ぐために，和漢薬(2013), No.721, 4-7.
14. 花尻（木倉）瑠理，内山奈穂子，河村麻衣子，緒方潤，合田幸広： 違法ドラッグを取り巻く国内外における現状と規制について．薬学雑誌(2013), 133, 31-40.
15. Kikura-Hanajiri,Ruri; Uchiyama, Nahoko; Goda, Yukihiro: Survey of current trends in the abuse of psychotropic substances and plants in Japan, Legal Medicine (2011), 13(3), 109-115.
16. 花尻（木倉）瑠理：Direct Analysis in Real Time (DART)-MSを用いた前処理不要の迅速分析法．FFI Journal (2010), 215(2), 137-143.
17. 花尻 瑠理：毛髪を中心とした代替生体試料中薬物分析, ぶんせき(2009)，2, 76-81.
18. 花尻（木倉）瑠理：日本における違法ドラッグ対策－指定薬物制度について－，ファルマシア(2008)，44(12), 1177-1182.
19. 木倉瑠理，中原雄二：依存性薬物の毛髪への取り込みに関する研究．国立衛生試験所報告(1998)，116, 30-45.
20. 木倉瑠理，毛髪分析：薬物の毛髪への移行性を決める要因とは？ ファルマシア(1998)，34(7), 708-709.1. 花尻（木倉）瑠理：危険ドラッグと合成カンナビノイド．Clinical Neuroscience, (2020), 38(8), 1033-1036.

単行本等

1. IARC Monographs Volume 126: Opium Consumption, Published by the International Agency for Research on Cancer, WHO (Lyon, France) (2021) ISBN 9789283201656 (pbk.) | ISBN 9789283201939 (ebook).（4. Mechanistic Evidence, 4.1 Absorption, distribution, metabolism and excretion執筆）
2. 花尻（木倉）瑠理：“漢方薬・生薬薬剤師講座テキスト1第5版”，法規制薬物及び麻薬原料植物，（財）日本薬剤師研修センター編集，東京(2020) p127-138.
3. 花尻（木倉）瑠理：第I章大麻とは，第VI章世界の大麻事情・欧州，第VII章大麻草およびその成分の医療での活用・欧州，「危険ドラッグ等の乱用防止のより効果的な普及啓発に関する研究」研究班編集，大麻問題の現状，真興交易医書出版部，東京（2020），pp.7-17, pp.80-87, pp.98-104．
4. 花尻（木倉）瑠理：第24章アルカロイドと危険ドラッグ，高山廣光編，アルカロイドの科学－生物活性を生み出す物質の探索から創薬の実際まで，pp491- 506．化学同人（2017）ISBN978-4-7598-1418-7．
5. 花尻（木倉）瑠理：I-6. 危険ドラッグの流通と健康危害，II-5. 大麻試験法，5.2 カンナビノイド受容体作動薬，II-7. 亜硝酸エステル類試験法，日本薬学会編，薬毒物試験法と注解2017，東京化学同人（2017）ISBN978-4-8079-0922-3．
6. 鈴木修，大野曜吉，須崎伸一郎，花尻（木倉）瑠理監修，薬毒物情報インデックス，日本医事新報社（2014） ISBN978-4-7849-4151-3
7. Kikura-Hanajiri, Ruri: The detection of mitragynine and its analogs. Edited by Raffa, Robert B, “Kratom and Other Mitragynines: The Chemistry and Pharmacology of Opioids from a Non-Opium Source”, pp.153-165, FL, USA, CRC Press (2014), ISBN 9781482225181.
8. Kikura-Hanajiri，Ruri: New Designer Drugs in Japan. Edited by Preedy, Victor R. “Neuropathology of Drug Addictions and Substance Misuse, Volume 2: Stimulants, Club and Dissociative Drugs, Hallucinogens, Steroids, Inhalants, and International Aspects”, pp1055-1065, London, UK, Academic Press (Elsevier) (2016), ISBN: 978-0-12-800212-4.
9. 花尻（木倉）瑠理：“漢方薬・生薬薬剤師講座テキスト3第4版”，法規制薬物及び麻薬原料植物，（財）日本薬剤師研修センター編集，東京(2015) ，pp.173-182.
10. 花尻（木倉）瑠理：“漢方薬・生薬薬剤師講座テキスト1第3版”，法規制薬物及び麻薬原料植物，（財）日本薬剤師研修センター編集，東京(2010) ，pp.213-223.