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Last updated date: March 30, 2015
 

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Advisory Committee on Health Effects of Endocrine Disruptors
The Supplement II to the Intermediary Report
1.5.2

 

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The endocrine disruptor issue is one of the fields that require particularly careful risk communication, because of discrepancies in perceptions in the public due to widespread public interest, disagreeing research results and technological advances.
Compared with common substances, of which mechanisms of adverse actions have largely been understood by conventional toxicology, endocrine disruptors are more difficult to comprehend because of the following features, making application of existing guidelines for risk communication also difficult:

  • The underlying hypothesis presented is beyond the conventional scope of adverse effects of chemicals.
  • The hypothesis is difficult to check, while it means a great thereat if it is true.
  • Studies for verification of hypothesis have yielded so far discrepant results.
  • Some results that were unpredictable by the conventional toxicology (e.g. the inverse U effect) have been reported.
Another problem about endocrine disruptors is that the endocrine disruption itself has not actually been confirmed in humans, except pharmacology of synthetic hormone preparations. This makes it difficult to apply existing guidelines which are designed for substances of which the nature of toxicity is already known.
Implementation of risk communication on endocrine disruptors should take these problems into account.

2.2 Persons concerned in risk communication
Persons concerned in risk communication include the administration (chiefly the Ministry of Health, Labor and Welfare), public1, enterprises, specialists/researchers and journalists.
Specialists/researchers play a key role as the information source.


1 Means general consumers.

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