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The Advisory Committee follows the two steps shown below in its
activities: |
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1.Surveying some tens of thousands chemical compounds
commonly found and possibly entering the human body for hormonal
activities and related properties as well as practical
applications, and prioritizing them for the ensuing definitive
studies
2.Conducting definitive studies, in the order of priority
established above, to determine if each compound really has
health effects |
The stepwise approach was adopted because |
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1. Among the regulated compounds known to have hormonal
activities, none has been found to need any urgent additional
measures, such as ban on use, within the capability of the
existing methodology of chemical hazard evaluation (see Note 1),
2. The definitive studies for hazard evaluation of such
compounds should be conducted in novel or improved methods which
take into consideration the whole life span of individuals (from
embryo to aged) and the neural and immune systems in addition to
the endocrine system (see Note 2), and
3. The definitive studies are probably extensive and need
therefore prioritization for handling tens of thousands of
compounds |
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