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[Results]
1. Organochlorine compounds
Gerhard et al. (1992) studied 28 cases and an in-hospital
control consisted of 441 subjects in Germany, and found
significantly higher levels of PCB138, 153 and 180 in serum of
the cases.
Boyd et al. (1995) found no difference in the levels of dioxins,
furans and PCBs between cases and control in the U.S.
Lebel et al. (1998) studied in Canada 86 cases against
in-hospital control of 70 subjects examined ventroscopically,
and found no significant differences in plasma levels of
chemicals or odds ratio between the two groups.
In a case-control study on Belgian female infertility
outpatients, Pauwels et al. (2001) found no difference in serum
PCB levels between cases diagnosed by ventroscopy and those with
etiology other than endometriosis.
A cross-sectional study in Belgium by Heilier et al. (2004)
found that serum PCB was higher in uterine adenomyosis and
comparable to control in endometriosis.
2. Diethylstilbestrol
Analysis of data on 397 infertile women in the U.S. by Stillman
showed that the prevalence of 50% ( 10/20) endometriosis for
women prenatally exposed to DES was higher than that for
unexposed women (39%, 164/377) but the difference was not
significant (P > 0.05).
In contrast, Berger et al. studied 100 American infertile women
and found a prevalence of 64% (32/50) for subjects prenatally
exposed to DES significantly higher than that for unexposed
subjects with corresponding ages (40%, 20/50).
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