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1) Causal relationship between exposure to
endocrine disruptors and human health problems has not been
established except for substances intended for pharmacological
action such as DES.
2) Immediate measures can be taken if the risk of and level of
exposure to specific substances are adequately evaluated if
- periods in which hormone regulation is unstable, such as the
fetal period, are not involved,
- unexpected synergy of more than one substance does not appear,
and
- unknown reactions in low doses do not exist.
(3) For solving the endocrine disruptor issue
This section reviews measures taken in Japan and other countries
against endocrine disruptors, presents basic policies on
chemical safety, information gathering and dissemination system,
international collaboration and comprehensive research. Specific
targets of research are categorized into (i) those needed for
further accumulation of data and (ii) those to be addressed by
up-to-date knowledge and leading-edge technology.
(4) Conclusion
The report is concluded with three propositions to be taking
into account in implementation of measures against endocrine
disruptors:
1) Many problems need further clarification to solve the
endocrine disruptor issue.
2) The issue transcends national borders.
3) The issue can persist over generations.
(5) Appendix
Studies on the substances listed below, which are used as
starting materials for plastics for eating utensils, are
summarized. It is stated that immediate actions such as ban is
not needed, but studies should be continued. General policies on
future studies are presented.
1) Polycarbonates (bisphenol A)
2) Polystyrene (styrene monomer, dimer and trimer)
3) Polyvinyl chloride (phthalic acid esters)
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