研究業績(2014~現在)
2023
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Nakayama T, Soga K.
Simple and quick detection of extended-spectrum β-lactamase and carbapenemase-encoding genes using isothermal nucleic acid amplification techniques.
J Microorg Control., 28(4): 145-152. (2023)
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Soga K, Taguchi C, Sugino M, Egu T, Narushima J, Yoshiba S, Takabatake R, Kondo K, Shibata N.
Investigation of genetically modified maize imported into Japan in 2021/2022 and the applicability of Japanese official methods.
Food Hyg. Saf. Sci., 64(6): 218-225. (2023)
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Taguchi C, Shibata N, Soga K, Yoshiba S, Narushima J, Sugino M, Kondo K.
Providing appropriate information to consumers boosts the acceptability of genome-edited foods in Japan.
GM Crops Food, 14(1): 1-14. (2023)
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Osawa H, Kurohara T, Ito T, Shibata N, Demizu Y.
CRBN ligand expansion for hematopoietic prostaglandin D2 synthase (H-PGDS) targeting PROTAC design and their in vitro ADME profiles.
Bioorg. Med. Chem., 84: 117259. (2023)
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Takabatake R, Kagiya Y, Futo S, Minegishi Y, Soga K, Shibata N, Kondo K.
Rapid Screening Detection of Genetically Modified Papaya by Loop-Mediated Isothermal Amplification.
Biol. Pharm. Bull., 46(5): 713-717. (2023)
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Goto K, Tamehiro N, Yoshida T, Hanada H, Sakuma T, Adachi R, Kondo K, Takeuchi I.
Novel machine learning method allerStat identifies statistically significant allergen-specific patterns in protein sequences.
J. Biol. Chem., 299(6): 104733. (2023)
2022
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Nishimaki-Mogami T, Ito S, Cui H, Akiyama T, Tamehiro N, Adachi R, Wakamatsu K, Ikarashi Y, Kondo K.
A cell-based evaluation of human tyrosinase-mediated metabolic activation of leukoderma-inducing phenolic compounds.
J. Dermatol. Sci., 108(2): 77-86. (2022)
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Kondo K, Taguchi C.
Japanese Regulatory Framework and Approach for Genome-edited Foods Based on Latest Scientific Findings.
Food Safety., 10(4):113-128. (2022)
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Shibata N, Soga K, Sugino M, Nakamura K, Narushima J, Yoshiba S, Egi T, Takabatake R, Kondo K.
Evaluation of conversion factor for rapid quantification of authorized genetically modified maize and soybean in Japan.
BPB Reports., 5(5):115-120. (2022)
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Soga K, Nakamura K, Egi T, Narushima J, Yoshiba S, Kishine M, Mano J, Kitta K, Takabatake R, Shibata N, Kondo K.
Development and Validation of a New Robust Detection Method for Low-Content DNA Using ΔΔCq-Based Real-Time PCR with Optimized Standard Plasmids as a Control Sample.
Anal Chem., 18;94(41):14475-14483. (2022)
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Narushima J, Kimata S, Shiwa Y, Gondo T, Akimoto S, Soga K, Yoshiba S, Nakamura K, Shibata N, Kondo K.
Unbiased prediction of off-target sites in genome-edited rice using SITE-Seq analysis on a web-based platform.
Genes Cells., 27(12):706-718. (2022) (DOI: 10.1111/gtc.12985)
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Takabatake R, Egi T, Soga K, Narushima J, Yoshiba S, Shibata N, Nakamura K, Kondo K, Kishine M, Mano J, Kitta K.
Development and Interlaboratory Validation of a Novel Reproducible Qualitative Method for GM Soybeans Using Comparative Cq-Based Analysis for the Revised Non-GMO Labeling System in Japan.
Anal Chem., 94(39):13447-13454. (2022)
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Murakami Y, Osawa H, Kurohara T, Yanase Y, Ito T, Yokoo H, Shibata N, Naito M, Aritake K, Demizu Y.
Structure-activity relationship study of PROTACs against hematopoietic prostaglandin D2 synthase.
RSC Med. Chem. (2022) (In press, DOI: 10.1039/d2md00284a)
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Xu H, Kurohara T, Takano R, Yokoo H, Shibata N, Ohoka N, Inoue T, Naito M, Demizu Y.
Development of rapid and facile solid-phase synthesis of PROTACs via a variety of binding styles.
ChemistryOpen., 11: e202200131. (2022)
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Sugano Y, Sakata K, Nakamura K, Hosokawa A, Kouguchi H, Suzuki T, Kondo K.
Loop-mediated isothermal amplification (LAMP) for rapid and easy identification of Omphalotus japonicus.
Food Chem (Oxf). (2022)
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Yanase Y, Tsuiji G, Nakamura M, Shibata N, Demizu Y.
Control of STING agonistic/antagonistic activity using amine-skeleton-based c-di-GMP analogues.
Int. J. Mol. Sci., 23: 6847. (2022)
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Shibata N, Cho N, Koyama H, Naito M.
Development of a degrader against oncogenic fusion protein FGFR3-TACC3.
Bioorg. Med. Chem. Lett., 60: 128584. (2022)
2021
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Goto K, Tamehiro N, Yoshida T, Hanada H, Sakuma T, Adachi R, Kondo K, Takeuchi I.
AllerStat: Finding Statistically Significant Allergen-Specific Patterns in Protein Sequences by Machine Learning.
bioRxiv. (2021)
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Tanaka H, Ito S, Ojika M, Nishimaki-Mogami T, Kondo K, Wakamatsu K.
The Oxidation of Equol by Tyrosinase Produces a Unique Di-ortho-Quinone: Possible Implications for Melanocyte Toxicity.
Int J Mol Sci., 22(17): 9145. (2021)
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Yokoo H, Shibata N, Endo A, Ito T, Yanase Y, Murakami Y, Fujii K, Hamamura K, Saeki Y, Naito M, Aritake K, Demizu Y.
Discovery of a Highly Potent and Selective Degrader Targeting Hematopoietic Prostaglandin D Synthase via In Silico Design.
J. Med. Chem., 64: 15868-15882. (2021)
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Nishimaki-Mogami T, Cui H, Soga K, Tamehiro N, Adachi R, Hachisuka A, Kondo K.
Statins repress multi-wall carbon nanotube-stimulated IL-1ß release through inhibiting the uptake by macrophages.
Toxocol. Lett., 350:S159. (2021)
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Narushima J, Kimata S, Shiwa Y, Gondo T, Akimoto S, Soga K, Yoshiba S, Nakamura K, Shibata N, Kondo K.
Strategy for detecting off-target sites in genome-edited rice.
bioRxiv. (2021)
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Cui H, Soga K, Tamehiro N, Adachi R, Hachisuka A, Hirose A, Kondo K, Nishimaki-Mogami T.
Statins repress needle-like carbon nanotube- or cholesterol crystal-stimulated IL-1β production by inhibiting the uptake of crystals by macrophages.
Biochem Pharmacol., 188:114580. (2021)
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Tamehiro N, Adachi R, Kondo K.
Assessment of Immune Responses in an Animal Model of Wheat Food Allergy via Epicutaneous Sensitization.
Methods Mol Biol., 2223: 37-47. (2021)
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Yokoo, H., Shibata, N., Naganuma, M., Murakami, Y., Fujii, K., Ito, T., Aratake, K., Naito, M., Demizu, Y.
Development of a Hematopoietic Prostaglandin D Synthase-Degradation Inducer.
ACS Med. Chem. Lett., 12:236-241. (2021)
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Taguchi C, Kishimoto Y, Fukushima Y, Kondo K.
Validation of food-frequency questionnaires for polyphenol intake in Japanese adults.
J. Nutr. Sci. Vitaminol., 67:72-75. (2021)
2020
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Takabatake R, Onishi M, Minegishi Y, Futo S, Soga K, Nakamura K, Kondo K, Mano J, Kitta K.
Development of a Novel Detection Method Targeting an Ultrashort 25 bp Sequence Found in Agrobacterium-Mediated Transformed GM Plants
J Agric Food Chem., 68(51): 15327-15334. (2020)
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高畠 令王奈, 大西 真理, 真野 潤一, 岸根 雅宏, 曽我 慶介, 中村 公亮, 近藤 一成, 橘田 和美
遺伝子組換えトウモロコシ定量のための内標比の算出
食品衛生学雑誌, 61(6): 235-238. (2020)
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Shibata, N., Shoka, N., Tsuji, G., Miyazawa, K., Ui-Tei, K., Akiyama, T., Naito, M.
Deubiquitylase USP25 prevents degradation of BCR-ABL protein and ensures proliferation of Ph-positive leukemia cells.
Oncogene, 39: 3867-3878. (2020)
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Aoki, W., Watanabe, M., Watanabe, M., Kobayashi, N., Terajima, J., Sugita-Konishi, Y., Kondo, K., Hara-Kudo, Y.
Discrimination between edible and poisonous mushrooms among Japanese Entoloma sarcopum and related species based on phylogenetic analysis and insertion/deletion patterns of nucleotide sequences of the cytochrome oxidase 1 gene.
Genes Genet Syst, 95: 1-7. (2020)
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Soga, K., Kimata, S., Narushimam J., Sato, S., Sato, E., Mano, J., Takabatake, R., Kitta, K., Kawakami, H., Akiyama, H., Kondo, K., Nakamura, K.
Development and Testing of an Individual Kernel Detection System for Genetically Modified Soybean Events in Non-identity-preserved Soybean Samples.
Biol. Pharm. Bull., 43: 1259-1266. (2020) (Highlighted Papers 2020 selected by Editor-in-Chief, 表紙採用)
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Narushima, J., Kimata, S., Soga, K., Sugano, Y., Kishine, M., Takabatake, R., Mano, J., Kitta, K., Kanamaru, S., Shirakawa, N., Kondo, K., Nakamura, K.
Rapid DNA template preparation directly from a rice sample without purification for loop-mediated isothermal amplification (LAMP) of rice genes.
Biosci Biotechnol Biochem., 84: 670-677. (2020)
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Soga, K., Nakamura, K., Ishigaki, T., Kimata, S., Ohmori, K., Kishine, M., Mano, J., Takabatake, R., Kitta, K., Nagoya, H., Kondo, K.
Development of a novel method for specific detection of genetically modified Atlantic salmon, AquAdvantage, using real-time polymerase chain reaction.
Food Chemistry, 305: 125426. (2020)
2019
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Fukutomi, Y., Teruuchi, Y., Nakatani, E., Minami, T., Sasagawa, Y., Fukushima, M., Kamide, Y., Sekiya, K., Saito, H., Teshima, R., Adachi, R., Taniguchi, M.
Allergen-specific IgG4 over time: Observation among adults with hydrolyzed wheat protein allergy.
Allergy, 74(8): 1548-1587. (2019)
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鍋師裕美, 堤智昭, 松田りえ子, 蜂須賀暁子, 穐山浩
ストロンチウム抽出カラムを用いた緊急時に適用可能な食品中のストロンチウム90(Sr-90)迅速分析法の確立
食品衛生学雑誌, 60(2): 7-15. (2019)
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近藤 一成, 坂田 こずえ, 加藤 怜子, 菅野 陽平, 武内 伸治, 佐藤 正幸
有毒クサウラベニタケ近縁種のリアルタイムPCR法による同定
食品衛生学雑誌, 60: 144-150. (2019)
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Soga, K., Nakamura, K., Ishigaki, T., Kimata, S., Ohmori, K., Kishine, M., Mano, J., Takabatake, R., Kitta, K., Nagoya, H., Kondo, K.
Data representing applicability of developed growth hormone 1 (GH1) gene detection method for detecting Atlantic salmon (Salmo salar) at high specificity to processed salmon commodities
Data Brief, 27: 104695. (2019)
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Tamehiro N, Nishida K, Sugita Y, Hayakawa K, Oda H, Nitta T, Nakano M, Nishioka A, Yanobu-Takanashi R, Goto M, Okamura T, Adachi R, Kondo K, Morita A, Suzuki H.
Ras homolog gene family H (RhoH) deficiency induces psoriasis-like chronic dermatitis by promoting TH17 cell polarization.
J Allergy Clin Immunol., 143: 1878-1891. (2019)
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Miyazaki A, Watanabe S, Ogata K, Nagatomi Y, Kokutani R, Minegishi Y, Tamehiro N, Sakai S, Adachi R, Hirao T.
Real-time PCR Detection Methods for Food Allergens (Wheat, Buckwheat, and Peanuts) Using Reference Plasmids.
J Agric Food Chem., 67, 5680-5686, (2019)
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Ku, W. L., Nakamura, K., Gao, W., Cui, K., Hu, G., Tang, Q., Ni, B., Zhao, K.
Single-cell chromatin immunocleavage sequencing (scChIC-Seq) to profile histone modification,
Nature Methods, 16, 323-325, (2019) (表紙採用)
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Kamemura N, Sugimoto M, Tamehiro N, Adachi R, Tomonari S, Watanabe T, Mito T:
Cross-allergenicity of crustacean and the edible insect Gryllus bimaculatus in patients with shrimp allergy
Mol Immunol.; 106: 127-134. (2019)
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Yamada, T., Soga, K., Hachinohe, M., Hachisuka, A.
Performance evaluation of the equipment for measuring radioactivity in whole foodstuffs without destructive sample preparation developed after the Fukushima NPP accident.
Radiat Prot Dosimetry, ncz112, https://doi.org/10.1093/rpd/ncz112 (2019)
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Teno N, Yamashita Y, Masuda A, Iguchi Y, Oda K, Fujimori K, Hiramoto T, Nishimaki-Mogami T, Une M, Gohda K.
Identification of potent farnesoid X receptor (FXR) antagonist showing favorable PK profile and distribution toward target tissues: Comprehensive understanding of structure-activity relationship of FXR antagonists.
Bioorg Med Chem. 27:2220-2227. (2019)
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矢野恒夫, 長谷川功紀, 蜂須賀暁子, 深瀬浩一, 平林容子.
アルファ線核医学治療のための薬剤開発の考察(その1).
医薬品医療機器レギュラトリーサイエンス 49(10) 676‐684, (2019)
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矢野恒夫, 長谷川功紀, 佐藤 彦, 蜂須賀暁子, 深瀬浩一, 平林容子.
アルファ線核医学治療のための薬剤開発の考察(その2).
医薬品医療機器レギュラトリーサイエンス 50(3) 122-134 (2019)
2018
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Nakamura, K., Ishigaki, T., Kobayashi, T., Kimata, S., Fujii, U., Soga, K., Kishine, M., Takabatake, R., Mano, J., Kitta, K., Kawakami, H., Nishimaki-Mogami, T., Kondo, K.
Identification of chickpea (Cicer arietinum) in foods using a novel real-time polymerase chain reaction detection method.
J Food Compost Anal, 71, 8-16, (2018)
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Nakanishi, K., Fujii, U., Nakamura, K., Ohtsuki, T., Kimata, S., Soga, K., Kishine, M., Mano, J., Takabatake, R., Kitta, K., Kawakami, H., Akiyama, H., Ikeda, M., Kondo, K.
Effect of sodium carboxymethyl cellulose in processed rice foods on detection of genetically modified rice-derived DNA.
Japanese Journal of Food Chemistry and Safety, 25, 77-85, (2018) (第14回日本食品化学学会論文賞受賞論文)
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Kawaguchi, N., Tomita, C., Naradate, R., Higami, T., Nakamura, K., Date, K., Aikawa, K., Ogawa, H.
A novel protocol for the preparation of active recombinant human pancreatic lipase from Escherichia coli.
J Biochem, 164, 407-414, (2018)
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Takabatake, R., Kagiya, Y., Minegishi, Y., Futo, S., Soga, K., Nakamura, K., Kondo, K., Mano, J., Kitta, K.
Rapid screening detection of genetically modified crops by loop-mediated isothermal amplification with a lateral flow dipstick.
J Agric Food Chem, 66, 7839-7845, (2018)
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Tamehiro N, Adachi R, Kimura Y, Sakai S, Teshima R, Kondo K:
Determining Food Allergens by Skin Sensitization in Mice.
Curr Protoc Toxicol.; 76: e48. (2018)
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Koizumi D, Shirota K, Oda H, Adachi R, Sakai, S, Akiyama H, Nishimaki-Mogami T, Teshima R:
Development and Evaluation of an Enzyme-Linked Immunosorbent Assay Using a Nonpoisonous Extraction System for the Determination of Crustacean Protein in Processed Foods
J AOAC Int.; 101(3): 798-804. (2018)
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岸根雅宏, 野口秋雄, 真野潤一, 高畠令王奈, 中村公亮, 近藤一成, 橘田和美
高度加工食品からの原材料農産物DNA検出の検討.
食品衛生学雑誌, 59, 151-156, (2018)
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曽我慶介,中村公亮,岸根雅宏,高嶋康晴,宮原平,木俣真弥,真野潤一,高畠令王奈,小関良宏,橘田和美,近藤一成.
リアルタイムPCRを用いたコーンフレーク中のトウモロコシゲノムDNA検出について
国立医薬品食品衛生研究所報告, 136, 31-39, (2018)
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中島治,近藤一成.
食用と考えられるゲノム編集動植物に関する調査.
国立医薬品食品衛生研究所報告, 136, 52-69, (2018)
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今村正隆,鍋師裕美,堤智昭,植草義徳,松田りえ子,前田朋美,曽我慶介,手島玲子,蜂須賀暁子,穐山浩.
市場流通食品中の放射性セシウム調査 (2014–2016年度)
食品衛生学雑誌 59(5), 239-247 (2018)
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Shoji M, Adachi R, Akiyama H
Japanese food allergen labeling regulation: An update.
J AOAC Int., 101(1), 8-13 (2018)
- Teno N, Yamashita Y, Iguchi Y, Fujimori K, Une M, Nishimaki-Mogami T, Hiramoto T, Gohda K
Nonacidic chemotype possessing N-acylated piperidine moiety as potent farnesoid X receptor (FXR) antagonists
ACS Med Chem Lett., 9(2), 78-83 (2018)
2017
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Mano J, Nishitsuji Y, Kikuchi Y, Fukudome S, Hayashida T, Kawakami H, Kurimoto Y, Noguchi A, Kondo K, Teshima R, Takabatake R, Kitta K.
Quantification of DNA fragmentation in processed foods using real-time PCR
Food Chem., 226, 149–155 (2017)
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Sugano Y, Sakata K, Nakamura K, Noguchi A, Nozomi F, Suzuki T, Kondo K
Rapid identification method of Omphalotus japonicas by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).
Shokuhin Eiseigaku Zasshi., 58, 113-123 (2017)(第58巻論文賞受賞)
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Kondo K, Nakamura K, Ishigaki T, Sakata K, Obitsu S, Noguchi A, Fukuda N, Nagasawa E, Teshima R, Nishimaki-Mogami T
Molecular phylogenetic analysis of new Entoloma rhodopolium-related species in Japan and its identification method using PCR-RFLP.
Scientific Reports., 7,14942 (2017)
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安達玲子,秋山雅治,加藤重城,森下直樹,黒田和彦,鮫島隆,吉田建介,川本康晴,布藤聡,大島慎司,久保田元,金丸俊介,今村正隆,塩野弘二,近藤一成,穐山浩
3種ELISA法の米粉中の小麦グルテン分析の妥当性評価
日本食品化学学会誌., 24(3):88-93 (2017)
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Teno N, Iguchi Y, Yamashita Y, Mori N, Une M, Nishimaki-Mogami T, Gohda K: Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists.
Discovery and optimization of benzimidazole derivatives as a novel chemotype of farnesoid X receptor (FXR) antagonists.
Bioorg Med Chem., 25(6), 1787-1794 (2017)
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Tamehiro N, Nishida K, Yanobu-Takanashi R, Goto M, Okamura T, Suzuki H
T-cell activation RhoGTPase-activating protein plays an important role in TH17-cell differentiation.
Immunol Cell Biol., 95(8), 729-735 (2017)
2016
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Takabatake, R., Masubuchi, T., Futo, S., Minegishi, Y., Noguchi, A., Kondo, K., Teshima R, Kurashima, T., Mano, J. and Kitta, K.
Selection of Suitable DNA Extraction Methods for Genetically Modified Maize 3272, and Development and Evaluation of an Event-Specific Quantitative PCR Method for 3272.
食品衛生学雑誌,57,1-6,(2016)
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Noguchi, A., Nakamura, K., Sakata, K., Sato-Fukuda, N., Ishigaki, T., Mano, J., Takabatake, R., Kitta, K., Teshima, R., Kondo, K. and Nishimaki-Mogami, T.
Development and Interlaboratory Validation of a Simple Screening Method for Genetically Modified Maize using ΔΔCq-based Multiplex Real-time PCR
Analytical Chemistry, 88(8), 4285–4293, (2016)
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鍋師 裕美,堤 智昭,植草 義徳,松田 りえ子,穐山 浩,手島 玲子,蜂須賀 暁子
調理による牛肉・山菜類・果実類の放射性セシウム濃度及び総量の変化
Radioisotopes 65(2): 45-58 (2016)
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Mano, J., Takashima, K., Futo, S., Minegishi, Y., Ninomiya, K., Noguchi, A., Kondo, K., Teshima, R., Takabatake, R. and Kitta, K.
Improvement of the group testing method to evaluate GM maize content.
食品総合研究所研究報告,80,57-68,(2016)
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Nakamura, K., Kondo, K., Akiyama, H., Ishigaki, T., Noguchi, A., Katsumata, H., Takasaki, K., Futo, S., Sakata, K., Fukuda, N., Mano, J., Kitta, K., Tanaka, H., Akashi, R., Nishimaki-Mogami, T.
Interlaboratory validation data on real-time polymerase chain reaction detection for unauthorized genetically modified papaya line PRSV-YK.
Data in Brief, 7, 1165-1170, (2016)
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Nakamura, K., Kondo, K., Akiyama, H., Ishigaki, T., Noguchi, A., Katsumata, H., Takasaki, K., Futo, S., Sakata, K., Fukuda, N., Mano, J., Kitta, K., Tanaka, H., Akashi, R., Nishimaki-Mogami, T.
Whole genome sequence analysis of unidentified genetically modified papaya for development of a specific detection method
Food Chemistry, 205, 272-279, (2016)
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曽我慶介、亀井俊之、蜂須賀暁子、最上(西巻)知子
食品中自由水に含まれるトリチウムの共沸蒸留による分離・分析法
食品衛生学雑誌、57(4)、81-88、(2016)(第57巻論文賞受賞)
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Ito, K., Yamamoto, T., Oyama, Y., Tsuruma, R., Saito, E., Saito, Y., Ozu, T., Honjoh, T., Adachi, R., Sakai, S., Akiyama, H., Shoji, M.
Food allergen analysis for processed food using a novel method to eliminate harmful reagents for both ELISA and lateral-flow tests.
Anal Bioanal Chem 408(22), 5973-84 (2016)
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Nakajima O, Nishimaki-Mogami T, Kondo K.
Cas9 in Genetically Modified Food Is Unlikely to Cause Food Allergy.
Biol Pharm Bull 39(11), 1876-1880 (2016)
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Tsukahara K, Takabatake R, Masubuchi T, Futo S, Minegishi Y, Noguchi A, Kondo K, Nishimaki-Mogami T, Mano J, Kitta K
Development and Evaluation of Event-Specific Quantitative PCR Method for Genetically Modified Soybean MON87701
Food Hyg. Saf. Sci., 57, 187-192 (2016)
- Miyahara T, Miyake N, Sawahuji K, Kitta K, Nakamura K, Kondo K, Ozeki Y.
Wheat DNA fragmentation of commercial processed foods.
Jap. J. Food Chem. Safety, 23, 141-148 (2016)
2015
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Takabatake, R., Onishi, M., Futo, S., Minegishi, Y., Noguchi, A., Nakamura, K., Kondo, K., Teshima, R., Mano, J., Kitta, K.
Comparison of the specificity, stability, and PCR efficiency of six rice endogenous sequences for detection analyses of genetically modified rice
Food Control, 50, 949-955, (2015)
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植草 義徳, 鍋師 裕美, 中村 里香, 堤 智昭, 蜂須賀 暁子, 松田 りえ子, 手島 玲子
市販流通食品中の放射性セシウム調査(平成24年度および平成25年度)
食品衛生学雑誌, 56 (2) 49-56, (2015)
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Uekusa, Y., Takatsuki, S., Tsutsumi, T., Matsuda, R., Akiyama, H., Hachisuka, A., Teshima, R., and Watanabe, T.
Follow-up investigation of polychlorinated biphenyl concentrations in fish from tsunami-stricken areas of Japan.
Organohalogen Compounds, 77, 432-435 (2015)
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Noguchi, A., Akiyama, H., Nakamura, K., Sakata, K., Minegishi, Y., Mano, J., Takabatake, R., Futo, S., Kitta, K., Teshima, R., Kondo, K. and Nishimaki-Mogami, T.
A novel trait-specific real-time PCR method enable quantification of genetically modified (GM) maize content in ground grain samples containing stacked GM maize.
Eur. Food Res. Technol. 240, 413-422, (2015)
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Hashimoto, H., Hongo, T., Hayashi, C., Nakamura, K., Nakanishi, K., Ikeda, M., Adachi, R., Akiyama, H., Teshima, R., Yano, T.
A method for the detection of shrimp/prawn and crab DNAs to identify allergens in dried seaweed products(特定原材料検査における乾燥海苔製品中のえび・かにDNA検出法の検討)
日本食品化学学会誌 22(1), 1-10 (2015)
-
Surveillance of Strontium-90 in Foods after the Fukushima Daiichi Nuclear Power Plant Accident.
Shokuhin Eiseigaku Zasshi. ;56(4):133-43 (2015)
-
Matsunaga K, Kuroda Y, Sakai S, Adachi R, Teshima R, Yagami A, Itagaki H.
Anaphylactic augmentation by epicutaneous sensitization to acid-hydrolyzed wheat protein in a guinea pig model.
J Toxicol Sci 40, 745-752 (2015)
-
Abdi R, Moore R, Sakai S, Donnelly CB, Mounayar M, Sackstein R
HCELL Expression on Murine MSC Licenses Pancreatotropism and Confers Durable Reversal of Autoimmune Diabetes in NOD Mice.
Stem Cells, 33(5), 1523-1531(2015)
-
Nakamura, K., Matsuoka, H., Nakashima, S., Kanda, T., Nishimaki-Mogami, T., Akiyama, H.
Oral administration of apple condensed tannins delays rheumatoid arthritis development in mice via down-regulation of T helper 17 (Th17) cell responses.
Molecular Nutrition & Food Research, 59, 1406-1410, (2015)
2014
-
Kurokawa, S., Kuroda, M., Mejima, M., Nakamura, R., Takahashi, Y., Sagara, H., Takeyama, N., Satoh, S., Kiyono, H., Teshima, R., Masumura, T. and Yuki, Y.
RNAi-mediated suppression of endogenous storage proteins leads to a change in localization of overexpressed cholera toxin B-subunit and the allergen protein RAG2 in rice seeds.
Plant Cell Rep., 33, 75-87 (2014)
-
Nakamura, R., Nakamura, R., Adachi, R., Hachisuka, A., Yamada, A., Ozeki, Y. and Teshima, R.
Differential analysis of protein expression in RNA-binding-protein transgenic and parental rice seeds cultivated under salt stress.
J. Proteome Res., 13, 489-495 (2014)
-
Mano, J., Hatano, S., Futo, S., Minegishi, Y., Ninomiya, K., Nakamura, K., Kondo, K., Teshima, R., Takabatake, R. and Kitta, K.
Development of direct real-time PCR system applicable to a wide range of foods and agricultural products.
Shokuhin Eiseigaku Zasshi., 25-33 (2014)
-
Nakamura, K., Kondo, K., Kobayashi, T., Noguchi, A., Ohmori, K., Takabatake, R., Kitta, K., Akiyama, H., Teshima, R. and Nishimaki-Mogami, T.
Identification and detection of genetically modified papaya resistant to papaya ringspot virus strains in Thailand.
Biol. Pharm. Bull., 37, 1-5 (2014)
-
Shimizu, Y., Kishimura, H., Kanno, G., Nakamura, A., Adachi, R., Akiyama, H., Watanabe, K., Hara, A., Ebisawa, M. and Saeki, H.
Molecular and immunological characterization of β'-component (Onc k 5), a major IgE-binding protein in chum salmon roe.
Int. Immunol., 26, 139-147 (2014)
-
Minegishi, Y., Mano, J., Takabatake, R., Nakamura, K., Kondo, K., Kato, Y., Kitta, K., Akiyama, H
Development of pBT63, a positive control plasmid for qualitative detection of genetically modified rice
Japanese Journal of Food Chemistry and Safety, 21, 48-56 (2014)
-
Cui H, Wu W, Okuhira K, Miyazawa K, Hattori T, Sai K, Naito M, Suzuki K, Nishimura T, Sakamoto Y, Ogata A, Maeno T, Inomata A, Nakae D, Hirose A, Nishimaki-Mogami T.
High-temperature calcined fullerene nanowhiskers as well as long needle-like multi-wall carbon nanotubes have abilities to induce NLRP3-mediated IL-1β secretion.
Biochem Biophys Res Commun, 452, 593-599 (2014)
-
植草 義徳, 鍋師 裕美, 堤 智昭, 蜂須賀 暁子, 松田 りえ子, 手島 玲子
トータルダイエット試料による食品を介した放射性物質の摂取量の推定
食品衛生学雑誌 55(4) 177-182(2014)
-
北川麻美子,中村公亮,近藤一成,生形省次,穐山 浩
野菜加工食品中の遺伝子組換えトマトに汎用される組換えDNA配列の検出について
食品衛生学雑誌, 55, 247-253, (2014)
-
田中 秀典, 北﨑 康生, 中村 公亮, 穐山 浩, 明石 良
遺伝子組換えパパイヤ(PRSV-YK)の簡易検出法の確立
育種学研究, 16, 158-161, (2014)
- 田口千恵,近藤一成
[解説] ゲノム編集食品の安全性確認の考え方と今後の課題
化学と生物, 61, 603-611. (2023)
- 安達玲子
食物アレルゲン表示制度におけるくるみの義務表示化と検査法、及び多機能アレルゲンデータベースADFSについて
食の安全と微生物検査, 13, 51-60. (2023)
- 柴田識人,内藤幹彦
脱ユビキチン化酵素阻害によるプロテインノックダウン
実験医学, 38 (14), 2337-2341 (2020)
- 井上貴雄,柴田識人
がんに対する核酸医薬品の開発
がん分子標的治療, 18 (1), 78-86 (2020)
- 蜂須賀暁子(編集幹事)他執筆者9名
第1.4章 放射能試験法、第2.5章 放射性物質試験法、第4.4.8章空気試験法
放射性物質.衛生試験法注解2015., pp.173-188,599-626,1212-1214,1242 (2020)
- 近藤一成
ゲノム編集技術を利用した食品等とその取扱い
食品機械装置., 12, 8-12 (2019)
- 安達玲子,五十嵐良明
医薬部外品・化粧品配合成分の安全性確保のための方策 ―加水分解コムギの特性を反映した医薬部外品原料規格の改正―
アレルギーの臨床., 37, 836-840 (2017)
- 曽我慶介,亀井俊之,近藤一成,最上(西巻)知子,蜂須賀暁子
食品中自由水のトリチウム汚染に対する実用的な簡便検査法の検討
Isotope News., 751, 72-74 (2017)
- 蜂須賀暁子
放射能分析における計数の統計的不確かさについて
食品衛生学雑誌, 57(2), J25-29, (2016)
- 蜂須賀暁子
食品中の放射性物質の安全性
月刊 地域保険、46(6)、20-31(2015)
- 安達玲子
アレルギー物質を含む食品(特定原材料)の検査方法にかかわる最近の動向
月刊フードケミカル,2015年1月号,62-65(2015)
- 安達玲子
その他(特定原材料に準ずるもの)
食物アレルギーの現状とリスク低減化食品素材の開発(監修森山達哉、穐山浩)pp55-58 シーエムシー出版(2015)
- 手島玲子、安達玲子、酒井信夫
アレルギー物質
食品衛生検査指針理化学編 pp.309-353 日本食品衛生協会(2015)
- 蜂須賀暁子、植草義徳、鍋師裕美、堤智昭、手島玲子、松田りえ子
トータルダイエット試料による食品からの放射性セシウム及びカリウムの摂取量推定
Isotope News、732、95-97、2015
- 酒井信夫
食物アレルゲン分析のネクストジェネレーション:LC-MSによる多重検出
ファルマシア, 51(5), 461 (2015)
- 松田りえ子、蜂須賀暁子
放射性物質測定値の統計学的特徴と食品中のセシウム検査
益社団法人日本食品衛生協会、2014.5.15出版
- 酒井信夫, 中村里香, 中村亮介, 安達玲子, 手島玲子
[解説] 加水分解コムギの経皮感作によるアレルギー
化学と生物, 52, 431-437 (2014)
- Sakai, S., Adachi, R., Teshima, R
Detection and control of eggs as a food allergen
Handbook of Food Allergen Detection and Control (Edited by Flanagan, S.) pp313-340 Woodhead Publishing (2014)
- 酒井信夫, 安達玲子, 中村亮介, 菊地博之, 渡邉敬浩, 佐々木和実, 西嶋桂子, 安宅花子, 最上(西巻)知子, 手島玲子
抗原性を有する加水分解コムギの分子プロファイリング
臨床免疫・アレルギー科, 62, 492-495 (2014)
- 近藤一成,中村公亮
次世代遺伝子組換え技術を用いた作物の現状と問題点
食品衛生学雑誌, 55, 231-246, (2014)
1.講義
-
安達玲子
「基礎から学ぶ特定原材料表示 ~導入の背景から新しい表示法における取扱いまで~」
日本食品衛生協会食品衛生研究所 食物アレルギー検査実習 (2018.7)
-
近藤一成
「きのこによる食中毒」
国立保健医療科学院平成29年度短期研修食品衛生危機管理研修 (2017.10)
-
安達玲子
「基礎から学ぶ特定原材料表示 ~導入の背景から新しい表示法における取扱いまで~」
日本食品衛生協会食品衛生研究所 食物アレルギー検査実習 (2017.7)
-
近藤一成
「きのこによる食中毒」
国立保健医療科学院平成27年度短期研修食品衛生危機管理研修 (2016.1)
-
近藤一成
「次世代遺伝子組換え技術」
国立保健医療科学院平成27年度短期研修食品衛生危機管理研修 (2016.1)
-
最上知子
「医薬品・食品・生活化学物質の安全を守る国立衛研の役割と研究」
平成26年度東北大学薬学部 薬学概論2 (2014.5)
-
中村公亮
「遺伝子組換え食品」
平成26年度JICA食品衛生のための行政能力強化 (2014.11)
-
安達玲子
「基礎から学ぶ特定原材料表示 ~導入の背景から製品の検査法まで~」
日本食品衛生協会食品衛生研究所 食物アレルギー検査実習 (2014.8)
2.講演
-
蜂須賀暁子
「食品の安全性について一緒に考えてみませんか」
平成30年度 食と放射能に関する説明会(2019.2)
-
蜂須賀暁子
「PETプローブの品質に関する課題」
第4回RIイメージング創薬活用研究会(2018.2)
-
蜂須賀暁子
「食品及び環境試料中の放射性物質の分析法」
第14回表示・起源分析技術研究懇談会講演会(2016.1)
3.その他
-
近藤一成
毒キノコにご用心
TOKYO FM 秋元才加のWeekly Japan!! (2016.9)
-
Kondo, K., Sakata, K., Kato, R.
Identification of toxic plants that cause severe food poisoning using real-time PCR.
9th International Symposium on Recent Advances in Food Analysis, Czech Republic, 2019年11月6日
-
Hosono, M., Yamada, T., Oriuchi, N., Ukon, N., Nagatsu, K., Ito, T., Yamanishi, H., Matsuda, T., Hachisuka, A., Nakamura, Y.
Construction of Safety Standards for Short-half-life Alpha Emitters by Grant of Nuclear Regulatory Agency of Japan.
EANM2019(欧州核医学会), Barcelona, 2019年10月16日
-
Ohoka. N., Cui, H., Tamehiro, H., Adachi, R., Okuhira, K., Naito, M., Kondo, K., Nishimaki-Mogami, T.
Identification of a sterol-responsive distal enhancer element for liver-specific ABCA1 gene expression – a novel mechanism for sterol-responsive hepatic ABCA1 gene regulation.
HDL Workshop: Structure, novel functions, and therapeutic applications, Spain, 2019年9月26日
-
Hachinohe, M., Yamada, T., Hachisuka, A., Soga, K., Horii, S., Miura, T.
Localization of radioactivity in dried shiitake mushrooms (Lentinula edodes).
5th International Conference on Environmental Radioactivity, Czech Republic, 2019年9月12日
-
Yamada, T., Hachisuka, A., Soga, K., Hachinohe, M.
Adaptability evaluation of the food screening without destructive sample preparation to ISO 19581.
5th International Conference on Environmental Radioactivity, Czech Republic, 2019年9月10日
-
Nishimaki-Mogami, T., Cui, H., Soga, K., Adachi, R., Tamehiro, N., Hachisuka, A., Kondo, K., Hirose, A.
Discovery of an inhibitor of multiwall carbon nanotubes-stimulated IL-1β secretion via inflammasome activation.
EUROTOX 2019, Finland, 2019年9月10日
-
Watanabe, S., Miyazaki, A., Hashimoto, M., Unno, H., Yonekawa, Y., Adachi, R., Hirao, T.
Novel DNA reference material by bioprinting IX: Application for quality control of the qualitative real-time PCR method for food allergens.
133rd AOAC Annual Meeting & Exposition, USA, 2019年9月10日
-
Adachi R, Tamehiro N, Kondo K, Miyazaki A, Watanabe S, Hirao T.
Interlaboratory validation of real-time PCR methods for the detection of wheat, buckwheat, and peanuts in processed foods.
133rd AOAC Annual Meeting & Exposition, USA, 2019年9月9日
-
Kondo, K., Kato, R., Sakata, K., Nakamura, K.
Mitochondria-resident non-releasable AIF mutant may regulate gene expressions related to cell differentiation and proliferation.
2018 ASCB EMBO Meeting, San Diego, CA, USA, 2018年12月8~12日
-
Nakamura, K., Kimata, S., Soga, K., Ohmori, K., Kishine, M., Mano, J., Takabatake, R., Kitta, K., Kondo, K.
Effect of food additives in processed foods on endogenous gene detection.
132nd AOAC Annual Meeting & Exposition, Toronto, Canada, 2018年8月26~29日
-
M. Hosono, N. Oriuchi, N. Ukon, K. Nagatsu, T. Ito, H. Yamanishi, T. Matsuda, T. Yamada, A. Hachisuka, Y. Nakamura.
Evidence-based safety management for short-lived alpha emitters by grant of Nuclear Regulatory Agency of Japan.
European Association of Nuclear Medicine ‘18 Düsseldorf (2018.10.15)
-
Yamada T, Hachisuka A, Soga K.
Performance evaluation of the equipment for measuring radioactivity in whole foodstuff without sample preparation techniques after the Fukushima NPP accident.
9th International Conference on High Level Environmental Radiation Areas, Aomori, Sep. 27, 2018
-
Soga, K., Nishimaki-Mogami, T., Kondo, K., Hachisuka, A.
Practical improvement of tritium analysis in foods using a liquid scintillation counting after azeotropic distillation method.
Health Physics Society 62nd Annual meeting, Radiation Safety Conference, Raleigh, North Carolina, July 2017
-
Young-Man Cho、Yasuko Mizuta, Takeshi Toyoda, Junichi Akagi, Tadashi Hirata, Reiko Adachi, Yoshie Kimura, Tomoko Nishimaki-Mogami, Kumiko Ogawa
Evaluation of the adjuvant effects of transcutaneously exposed silver nanoparticles with different size in mouse model
55th SOT 2016年3月
-
Nabeshi, H., Tsutsumi, T., Y. Uekusa, Hachisuka, A., Matsuda, R., Teshima, R., Akiyama, H., Teshima, R.
Estimation of Dietary Intake of Strontium-90 in Six Regions in Japan after the Fukushima Daiichi Nuclear Power Plant Accident.
Health Physics Society 61st Annual Meeting, Spokane, Washington (2016.7)
-
Uekusa Y, Akiyama H, Takatsuki S, Maeda T, Tsutsumi T, Watanabe T, Matsuda R, Hachisuka A
Analysis of polychlorinated biphenyls in fish from tsunami-stricken areas of Japan
Dioxin 2016 (2016.08, Firenze,Italy)
-
Reiko Adachi, Norimasa Tamehiro, Tomoko Nishimaki-Mogami, Kazunari Kondo
Investigation of residual amounts of soybean and wheat proteins in Japanese traditional fermented food
AOAC 130th Annual Meeting & Exposition(2016.9) (Dallas)
-
Teshima, R., Nakamura, R., Adachi, R., Shindo, T., Yamada, A., Ohsawa, M., Ozeki, Y
Differential analysis of protein expression in RNA binding protein-transgenic and parental rice seeds cultivated under salt stress and allergenicity test of the rice extracts
Society of Toxicology 54th Annual Meeting and ToxExpo (2015.3) (San Diego, USA)
-
Nabeshi, H., Tsutsumi, T., Uekusa Y, Hachisuka, A., Matsuda, R., Teshima, R
Surveillance of Strontium-90 in Foods after the Fukushima Daiichi Nuclear Power Plant Accident.
Health Physics Society 60th Annual Meeting, Baltimore, Maryland (2015.7)
-
Uekusa Y, Takatsuki S, Tsutsumi T, Matsuda R, Akiyama H, Hachisuka A, Teshima R, Watanabe T
Follow-up investigation of polychlorinated biphenyl concentrations in fish from tsunami-stricken areas of Japan.
Dioxin 2015, Sao Paulo, Brazil (2015.8)
-
Kondo K, Sakata K, Nakamura K, Noguchi A, Fukuda N, Ishigaki T, Nishimaki-Mogami T.
Rapid identification of poisonous Entoloma rhodopolium and edible E. sarcopum mushrooms using PCR-restriction fragment length polymorphism and real-time PCR
7th International Symposium on Recent Advances in Food Analysis, Prague, Czech Republic, 2015年11月
-
Kondo K, Sakata K, Nakamura K, Noguchi A, Fukuda N, Ishigaki T, Nishimaki-Mogami T.
A new analytical methodology for unknown genetically modified organisms using linear-amplified mediated PCR (LAM-PCR)
7th International Symposium on Recent Advances in Food Analysis, Prague, Czech Republic, 2015年11月
-
Hiroshi Akiyama, Reiko Adachi
Japanese Framework for labeling and testing of allergens in foods
Pacifichem 2015 2015年12月
-
Reiko Adachi, Shinobu Sakai, Hiroshi Akiyama, Tomoko Nishimaki-Mogami
Enzyme-linked immunosorbent assay for detecting food allergens in processed food in Japan
Pacifichem 2015(2015.12) (Honolulu)
-
Nakamura, K., Ishigaki, T., Hanada, K., Akimoto, S., Kondo, K., Nishimaki-Mogami, T.
DNA methylation pattern analysis of common plant virus promoter used to develop genetically modified crops
Pacifichem 2015(2015.12) (Honolulu)
-
Reiko Adachi, Shinobu Sakai, Tomoko Nishimaki-Mogami
Food allergen labeling regulation in Japan and recent topics.
8th Workshop on Food Allergen Methodologies & APEC Introduction to Food Allergies and Allergen Detection Methods 2014年5月
-
Nabeshi, H., Tsutsumi, T., Hachisuka, A., Matsuda, R., Teshima, R.
Concentrations of Radioactive Cesium and Strontium in Wild Animal Meat and Bone
Health Physics Society 59th Annual Meeting, Baltimore, Maryland (2014.7)
-
Yohei Kataoka, Takahiro Watanabe, Tomoko Hayashi, Rieko Matsuda, Akiko Hachisuka, Reiko Teshima
Surveillance of concentrations of harmful elements in foods purchased in areas affected by the great east Japan earthquake
Dioxin 2014 (2014.9)
-
Yoshinori Uekusa, Satoshi Takatsuki, Takahiro Watanabe, Yohei Kataoka, Tomoaki Tsutsumi, Rieko Matsuda, Akiko Hachisuka, Reiko Teshima
Concentration of polychlorinated biphenyls in commercially available fish obtained from tsunami-stricken areas of Japan
Dioxin 2014 (2014.9)
-
Nakamura, K., Kondo, K., Akiyama, H., Kobayashi, T., Noguchi, A., Nagoya, H., Takabatake, R., Kitta, K., Plouffe, D., Buchanan, J., Nishimaki-Mogami, T.
A novel transgenic construct-specific real-time PCR detection method for genetically modified salmon in foods
128th AOAC Annual Meeting & Exposition (2014.9) (Florida, USA)
-
Sakai, S., Nakamura, R., Adachi, R., Fukutomi, Y., Saito, Y., Nishimaki-Mogami, T., Teshima, R.
Experimental Assessments of the Cross-reactivity of IgE from Patients Sensitized with Acid-Hydrolysed Wheat Protein in a Cosmetic Soap.
3rd Food Allergy and Anaphylaxis Meeting (2014.10) (Dublin, Ireland)
-
Adachi, R.
Food Allergen Labelling and New Analytical Method in Japan
International Food Allergy Seminar for 72th Kasetsart University (2014.11) (Bangkok, Thailand)
2022 第59回全国衛生化学技術協議会年会、川崎、10月
-
吉場聡子,成島純平,曽我慶介,杉野御祐,柴田識人,近藤一成
遺伝子組換え食品の同定に資する新たなゲノム解析技術の検討
-
柴田識人,成島純平,曽我慶介,吉場聡子,近藤一成
ゲノム編集食品における外来性遺伝子の残存を評価する全ゲノムシークエンスデータ解析の標準化に向けた取り組み
-
田口千恵,近藤一成
ゲノム編集食品に対する国民理解の向上を目指した取り組み
-
成島純平,杉野御祐,曽我慶介,吉場聡子,柴田識人,近藤一成
NGSを用いた網羅的なオフターゲット変異候補部位予測法の高GABA産生ゲノム編集トマトへの適用と検証
2021 第58回全国衛生化学技術協議会年会、名古屋(Web)、11月
-
吉場聡子,成島純平,曽我慶介,柴田識人,近藤一成
安全性未承認の遺伝子組換えナタネの試験法開発
-
柴田識人,曽我慶介,成島純平,吉場聡子,江木智宏,高畠令王奈,近藤一成
遺伝子組換えダイズ・トウモ ロコシ定量のための内標比の算出
-
曽我慶介,成島純平,吉場聡子,江木智宏,真野潤 一,高畠令王奈,橘田和美,中村公亮,柴田識人,近藤一成
「遺伝子組換えでない」表示確認に係る新定性検査法の試験室間共同試験による妥当性評価
-
安達玲子,為広紀正,油井賢也,近藤一成
アレルゲン を含む食品「くるみ」の検査法開発のための標準品調製法に関する検討
2020 第57回全国衛生化学技術協議会年会、宮崎(Web)、11月
-
曽我慶介,木俣真弥,成島純平,佐藤咲子,佐藤恵美,真野潤一,高畠令王奈,橘田和美,川上浩,吉場聡子,柴田識人,穐山浩,中村公亮,近藤一成
新しい遺伝子組換え表示の妥当性を確保するための外国産 遺伝子組換え不十分大豆の流通実態調査
-
成島純平,吉場聡子,曽我慶介,高畠令王奈,橘田和美,中村公亮,柴田識人,近藤一成
安全性未審査の遺伝子組換えコムギ(MON71400,MON71500及びMON71600)を対象とした系統個別検知法の評価
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五十嵐良明,酒井信夫,佐々木和実*,小濱とも子,秋山卓美,安達玲子
化粧品に用いられるタンパク質性成分の分子プロファイル解析及び欧米における規制基準調査
2019 第56回全国衛生化学技術協議会年会、広島、12月
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鍋師裕美, 松田りえ子, 今村正隆, 曽我慶介, 堤 智昭, 穐山 浩, 蜂須賀暁子
2018年度公表の食品中放射性物質濃度検査データの解析
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成島純平,中村公亮,木俣真弥,曽我慶介,真野潤一,高畠令王奈,橘田和美,近藤一成
安全性未審査グリホサート除草剤耐性遺伝子組換えコムギの国内への流入を未然に防止するための検査法の確立
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曽我慶介,中村公亮,岸根雅宏,真野潤一,高畠令王奈,橘田和美,近藤一成
リアルタイムPCRを用いたコーンフレーク中のトウモロコシゲノムDNA検出法の検討
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大森清美、成島純平、木俣真弥、曽我慶介、近藤一成、中村公亮
遺伝子組換えパパイヤおよびトマトの検出を目的としたドライフルーツ中の内在性遺伝子検出に関する実態調査
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為広紀正,安達玲子,嘉村志帆,良永裕子,近藤一成
アレルゲンを含む食品の確認検査のための市販DNA抽出キットの精製効率に関する検討
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小濱とも子,五十嵐良明,酒井信夫,佐々木和実,秋山卓美,安達玲子
化粧品に用いられる食物由来タンパク質成分の分子量測定法に関する検討
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坂田こずえ,加藤怜子,近藤一成
自然毒データベースの改定について
2018 第55回全国衛生化学技術協議会年会、神奈川、11月
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曽我慶介,松田りえ子,鍋師裕美,今村正隆,堤智昭,近藤一成,蜂須賀暁子
2017年度公表の食品中放射能検査結果の解析
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曽我慶介,中村公亮,岸根雅宏、高嶋康晴、宮原平、木俣真弥、真野潤一、高畠令王奈、小関良宏、橘田和美、近藤一成
リアルタイムPCRを用いたコーンフレーク中のトウモロコシゲノムDNA検出法の検討
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木俣真弥,中村公亮,曽我慶介,岸根雅宏,高畠令王奈,橘田和美,近藤一成
遺伝子組換えバレイショY9系統とX17系統を対象とした検知試験法の開発
2017 第54回全国衛生化学技術協議会年会、奈良、11月
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曽我慶介,近藤一成,蜂須賀暁子
食品中の放射性核種ポロニウム分析法検討
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菅野陽平,坂田こずえ,野口秋雄,中村公亮,青塚圭二,佐藤正幸,鈴木智宏,近藤一成
LAMP法を用いた有毒キノコ迅速判別法の構築
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藤井宇希,中西希代子,中村公亮,大槻 崇,曽我慶介,岸根雅宏,高畠令王奈,橘田和美,川上浩,穐山浩,池田惠,近藤一成
コメ加工食品中のカルボキシメチルセルロースナトリウムがDNA抽出精製効率,並びに,遺伝子組換え食品検査へ与える影響について
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坂田こずえ,野口秋雄,加藤怜子,篠崎淳一,紺野勝弘,近藤一成
リアルタイムPCR法による有毒植物の検出法開発
2016 第53回全国衛生化学技術協議会年会、青森、11月
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野口秋雄,中村公亮,坂田こずえ,石垣拓実,加藤怜子,真野潤一,高畠令王奈,橘田和美,最上(西巻)知子,近藤一成
遺伝子組換えトウモロコシ粒検査法の簡易化
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安達玲子、土切美穂、板垣宏、為広紀正、最上(西巻)知子、近藤一成
健康食品等の原材料となるキトサン・グルコサミン類の甲殻類タンパク質含有量に関する検討
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中村公亮,石垣拓実,野口秋雄,坂田こずえ,加藤怜子,真野潤一,橘田和美,最上(西巻)知子,近藤一成
アクリルアミド産生低減並びに打撲黒班低減を目的に開発された遺伝子組換えジャガイモ(J3、F10、E12系統)の検知法開発(第1報)
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坂田こずえ,中村公亮,野口秋雄,石垣拓実,加藤怜子,近藤一成
ITS-RPB2領域を用いたクサウラベニタケ系統分類と中毒事例検体の分析
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中島 治、最上(西巻) 知子、近藤 一成
遺伝子組換え食品におけるCas9の免疫原性について
2015 第52回全国衛生化学技術協議会年会、静岡、12月
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野口秋雄,中村公亮,坂田こずえ,福田のぞみ,石垣拓実,真野潤一,高畠令王奈,橘田和美,近藤一成,最上(西巻)知子
遺伝子組換えトウモロコシの新規スクリーニング検査法の妥当性評価
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中村公亮,近藤一成,穐山浩,石垣拓実,野口秋雄,坂田こずえ,福田のぞみ,大森清美,布施谷実聡,川上浩,田中秀典,明石良,真野潤一,橘田和美,最上(西巻)知子
我が国における未承認遺伝子組換えパパイヤの食品への混入に関する事例と検知法開発の現状
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鍋師裕美, 堤 智昭, 植草義徳, 松田りえ子, 蜂須賀暁子, 手島玲子, 穐山 浩
牛肉・山菜類・果実類中の放射性セシウムの調理影響に関する検討
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酒井信夫、安達玲子、最上(西巻)知子、佐久間智宏、大坂郁恵、石井里枝
マイクロチップ電気泳動システムを利用した特定原材料通知PCR法の機関間および機種間検証
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五十嵐良明、秋山卓美、酒井信夫、安達玲子、手島玲子
医薬部外品原料「加水分解コムギ末」規格の改訂検討状況
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植草義徳,鍋師裕美,堤智昭,蜂須賀暁子,松田りえ子,穐山浩,手島玲子
放射性セシウムが検出された食品のプルトニウム分析
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曽我慶介、亀井俊之、蜂須賀暁子、最上(西巻)知子
食品中の放射性物質トリチウム試験法の検討
2014 第51回全国衛生化学技術協議会年会、別府、11月
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蜂須賀暁子、植草義徳、鍋師裕美、堤智昭、松田りえ子、最上知子
放射能測定における不確かさ-試料形状
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近藤一成
植物性自然毒の検査法及びデータベースの整備、活用について
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野口秋雄,坂田こずえ,真野潤一,中村公亮,高畠令王奈,峯岸恭孝,橘田和美,穐山浩,手島玲子,近藤一成,最上(西巻)知子
2010年度米国産不分別トウモロコシ試料における遺伝子組換えトウモロコシの混入率と系統分析
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植草義徳、鍋師裕美、片岡洋平、渡邉敬浩、堤智昭、蜂須賀暁子、松田りえ子、手島玲子
原子力発電所事故の影響を受けた食品中のウラン濃度の調査
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松田りえ子、堤 智昭、鍋師裕美、植草義徳、蜂須賀暁子、手島玲子
都道府県等が実施した食品中の放射性物質検査結果の解析
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野口秋雄
遺伝子組換えトウモロコシの新規スクリーニング検査法
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中村公亮、近藤一成、小林友子、坂田こずえ、野口秋雄、名古屋博之、真野潤一、橘田和美、最上(西巻)知子
成長ホルモン遺伝子を組換えた遺伝子組換えサケ検知法の試験室間共同試験による妥当性確認
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酒井信夫, 安達玲子, 穐山浩, 最上(西巻)知子
「アレルギー物質を含む食品の検査方法の改良法の評価に関するガイドライン」に基づく新・旧特定原材料ELISAキットの同等性評価
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Nakajima, O., Nakamura, K., Kondo, K., Akiyama, H. and Teshima, R.
Method of detecting genetically modified chicken containing human erythropoietingene.
Biol. Pharm Bull., 36, 1454-1459 (2013)
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Kurokawa, S., Nakamur,a R., Mejima, M., Kozuka-Hata, H., Kurod,a M., Takeyama, N., Oyama, M., Satoh, S., Kiyono, H., Masumura, T., Teshima, R. and Yuki, Y.
MucoRice-cholera toxin B-subunit, a rice-based oral cholera vaccine, down-regulates the expression of α-amylase/trypsin inhibitor-like protein family as major rice allergens.
J. Proteome Res., 12, 3372-3382 (2013)
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Nakamura, K., Maeda, Y., Morimoto, K., Katayama, S., Kondo, K. and Nakamura, S.
Functional expression of amyloidogenic human stefins A and B in Pichia pastoris using codon optimization.
Biotech. Appl. Biochem., 60, 283-288 (2013)
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Nakamura, K., Akiyama, H., Kawano, N., Kobayashi, T.,Yoshimatsu, K., Mano, J., Kitta, K., Ohmori, K., Noguchi,A., Kondo, K. and Teshima, R.
Evaluation of real-time PCR detection methods for detecting rice products contaminated by rice genetically modified with a CpTI-KDEL-T-nos transgenic construct.
Food Chem., 141, 2618-2624 (2013)
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Noguchi, A., Nakamura, K., Sakata, K., Kobayashi, T., Ohmori, K., Kasahara, M., Takabatake, R., Kitta, K., Akiyama, H., Kondo, K. and Teshima, R.
Interlaboratory validation study of an event-specific real-time polymerase chain reaction detection method for genetically modified 55-1 papaya.
J. AOAC Int., 96, 1054-1058 (2013)
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Takabatake, R., Noritake, H., Noguchi, A., Nakamura, K., Kondo, K., Akiyama, H., Teshima, R., Mano, J. and Kitta, K.
Comparison of DNA extraction methods for sweet corn and processed sweet corns.
Shokuhin Eiseigaku Zasshi., 54, 309-315 (2013)
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Obitsu, S., Sakata, K., Teshima, R. and Kondo, K.
Eleostearic acid induces RIP1-mediated atypical apoptosis in a kinase-independent manner via ERK phosphorylation, ROS generation and mitochondrial dysfunction.
Cell Death Dis., 4, e674 (2013)
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Ohmori, K., Nakamura, K., Kasahara, M., Takabatake, R., Kitta, K., Fujimaki, T., Kondo, K., Teshima, R. and Akiyama, H.
A novel DNA extraction and purification method using an ion-exchange resin type kit for the detection of genetically modified papaya in processed papaya products.
Food Control, 32, 728-735 (2013)
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Nakamura, K., Minamitake, Y., Nakamura, K., Kobayashi, T., Noguchi, A., Takabatake, R., Kitta, K., Hashimoto, H., Kawakami, H., Kondo, K., Teshima, R. and Akiyama, H.
Development of PCR primers designed for sensitive detection of genetically modified potato DNA in processed foods.
Jpn. J. Food Chem.Safety., 20, 161-169 (2013)
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Nakamura, K., Sakagami, H., Asanuma-Date, K., Nagasawa, N., Nakahara, Y. , Akiyama, H. and Ogawa, H.
Immobilized glycosylated Fmoc-amino acid for SPR: comparative studies of lectin-binding to linear or biantennary diLacNAc structures.
Carbohydr. Res., 382, 77-85 (2013)
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Igarashi, N., Takeguchi, A., Sakai, S., Akiyama, H., Higashi, K. and Toida, T.
Effect of molecular sizes of chondroitin sulfate on interaction with L-selectin.
Int. J. Carbohydr. Chem., 2013, 1-9 article ID 856142 (2013)
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Sakai, S., Adachi, R., Akiyama, H. and Teshima, R.
Validation of Quantitative and Qualitative Methods for Detecting Allergenic Ingredients in Processed Foods in Japan.
J. Agric. Food Chem., 61, 5675-5680 (2013)
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Nakamura, R, Nakamura, R, Adachi, R, Itagaki, Y., Fukutomi, Y. and Teshima, R.
Evaluation of allergenicity of acid-hydrolyzed wheat protein using an in vitro elicitation test.
Int. Arch. Allergy Immunol., 160, 259-264 (2013)
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Mano, J., Masubuchi, T., Hatano, S., Futo, S., Koiwa, T., Minegishi, Y., Noguchi, A., Kondo, K., Akiyama, H., Teshima, R., Kurashima, T., Takabatake, R. and Kitta, K.
Development and validation of event-specific quantitative PCR method for genetically modified maize LY038.
Shokuhin Eiseigaku Zasshi., 54, 25-30 (2013)
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Nakamura, K., Akiyama, H., Takahashi, Y., Kobayashi, T., Noguchi, A., Ohmori, K., Kasahara, M., Kitta, K., Nakazawa, H., Kondo, K. and Teshima R.
Application of a qualitative and quantitative real-time polymerase chain reaction method for detecting genetically modified papaya line 55-1 in papaya products.
Food Chem., 136, 895-901 (2013)
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Ohmori, K., Nakamura, K., Kasahara, M., Takabatake, R., Kitta, K., Fujimaki, T., Kondo, K., Teshima, R. and Akiyama, H.
A DNA extraction and purification method using an ion-exchange resin type kit for the detection of genetically modified papaya in processed papaya products.
Food Control., 32, 728-35 (2013)
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Mano, J., Harada, M., Takabatake, R., Furui, S., Kitta, K., Nakamura, K., Akiyama, H., Teshima, R., Noritake, H., Hatano, S., Futo, S., Minegishi, Y. and Iizuka, T.
Comprehensive GMO detection using real-time PCR array: single-laboratory validation.
J AOAC Int., 95, 508-516 (2012)
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Nakamura, R., Ishiwatari, A., Higuchi, M., Uchida, Y., Nakamura, R., Kawakami, H., Urisu, A. and Teshima, R
Evaluation of the luciferase assay-based in vitro elicitation test for serum IgE.
Allergol Int., 61, 431-437 (2012)
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Adachi, R., Nakamura, R., Sakai, S., Fukutomi, Y. and Teshima, R.
Sensitization to acid-hydrolyzed wheat protein by transdermal administration to BALB/c mice, and comparison with gluten.
Allergy., 67, 1392-1399 (2012)
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Watanabe, S., Taguchi, H., Temmei, Y., Hirao, T., Akiyama, H, Sakai, S., Adachi, R., Urisu, A., Teshima, R.
Specific detection of potentially allergenic peach and apple in foods using polymerase chain reaction.
J. Agric. Food Chem., 60, 2108-2115 (2012)
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Nakamura, K., Ohtsuki, T., Mori, H., Hoshino, H., Hoque, A., Oue, A., Kanou, F., Sakagami, H., Tanamoto, K., Ushijima, H., Kawasaki, N., Akiyama, H., Ogawa, H.
Novel anti-HIV-1 activity produced by conjugating unsulfated dextran with poly L-lysine.
Antiviral Res., 94, 89-97 (2012)
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Shindo, T., Kanazawa, Y., Saito Y., Kojima, K., Ohsawa, M., Teshima, R.
Effective induction of oral anaphyaxis to ovalbumin in mice sensitized by feeding of the antigen with aid of oil emulsion and salicylate.
J. Toxicol. Sci., 37, 307-315 (2012)
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Taguchi, H., Watanabe, S., Temmei, Y., Hirao, T., Akiyama, H, Sakai, S., Adachi, R., Sakata, K., Urisu, A., Teshima, R.
Differential detection of shrimp and crab for food labeling using polymerase chain reaction.
J. Agric. Food Chem., 59, 3510-3519 (2011)
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Matemu, A. O., Nakamura, K., Kayahara, H., Murasawa, H., Katayama, S., Nakamura, S.
Enhanced antiviral activity of soybean β-conglycinin-derived peptides by acylation with saturated fatty acids.
J. Food Sci., 76, M299-304 (2011)
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Ohashi-Suzuki, M., Yabu, Y., Ohshima, S., Nakamura, K., Kido, Y., Sakamoto, K., Kita, K., Ohta, N., Suzuki, T.
Differential kinetic activities of glycerol kinase among African trypanosome species: Phylogenetic and therapeutic implications.
J. Vet. Med. Sci., 73, 615-621 (2011)
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Nakamura, K., Akiyama, H., Ohmori, K., Takahashi, Y., Takabatake, R., Kitta, K., Nakazawa, H., Kondo, K., Teshima, R.
Identification and detection method for genetically modified papaya resistant to papaya ringspot virus YK strain.
Biol. Pharm. Bull., 34, 1648-1651 (2011)
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Kondo, K., Obitsu, S., Teshima R.
α-Synuclein aggregation and transmission are enhanced by leucine-rich repeat kinase 2 in human neuroblastoma SH-SY5Y cells.
Biol. Pharm. Bull., 34, 1078-1083 (2011)
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中村里香, 中村亮介, 手島玲子
古代米(赤米・黒米)のアレルゲン発現プロテオミクス解析
日本食品化学学会誌, 18, 143-149 (2011)
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佐藤里絵, 中村里香, 手島玲子
イムノプロテオミクス手法を用いたソバIgE 結合タンパク質の網羅的検出
日本食品化学学会誌, 18, 103-109 (2011)
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Satoh, R., Nakamura, R., Komatsu, A., Oshima, M., Teshima, R.
Proteomic analysis of known and candidate rice allergens between non-transgenic and transgenic plants.
Regul. Toxicol. Pharmacol., 59, 437-444 (2011)
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Nakamura, R., Satoh, R., Nakamura, R., Shimazaki, T., Kasuga, M., Yamaguchi-Shinozaki, K., Kikuchi, A., Watanabe, K. N., Teshima, R.
Immunoproteomic and 2D-DIGE Analysis of Arabidopsis DREB1A-Transgenic Potato
Biol Pharm Bull., 33(8), 1418-25 (2010)
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Nakamura, R., Nakamura, R., Watanabe, K., Oka, K., Ohta, S., Mishima, S., Teshima, R.
Effects of propolis from different areas on mast cell degranulation and identification of the effective components in propolis
Int Immunopharmacol., 10(9), 1107-12 (2010)
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Nakamura, R., Uchida, Y., Higuchi, M., Nakamura, R., Tsuge, I., Urisu, A. and Teshima, R.
A convenient and sensitive allergy test: IgE crosslinking-induced luciferase expression in cultured mast cells.
Allergy, 65, 1266-1273 (2010).
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Teshima, R., Nakamura, R., Satoh, R., Nakamura, R.
2D-DIGE analysis of rice proteins from different cultivars
Regul Toxicol Pharmacol., 58(3 Suppl), S30-5 (2010)
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Satoh, R., Koyano, S., Takagi, K., Nakamura, R., Teshima, R.
Identification of an IgE-binding epitope of a major buckwheat allergen, BWp16, by SPOTs assay and mimotope screening
Int Arch Allergy Immunol., 153(2), 133-40 (2010)
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Hachisuka, A., Nakamura, R., Sato, Y., Nakamura, R., Shibutani, M., and Teshima, R.
Effects of perinatal exposure to the brominated flame-retardant hexabromocyclododecane (HBCD) on the developing immune system in rats
Bull. Natl. Inst. Health Sci., 127, 58-64 (2010)
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Oguchi, T., Onishi, M., Mano, J., Akiyama, H., Teshima, R., Futo, S., Furui, S., Kitta, K.
Development of multiplex PCR method for simultaneous detection of four events of genetically modified maize: DAS-59122-7, MIR604, MON863 and MON88017
Food Hyg. Saf. Sci.,51, 92-100 (2010)
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Sato, Y., Akiyama, H., Matsuoka, H., Sakata, K., Nakamura, R., Ishikawa, S., Inakuma, T., Totsuka, M., Sugita-Konishi, Y., Ebisawa, M., Teshima, R.
Dietary Carotenoids Inhibit Oral Sensitization and the Development of Food Allergy
J. Agric. Food Chem., 58, 7180-7186 (2010)
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Abbott, M., Hayward, S., Ross, W., Godefroy, S.B., Ulberth, F., Van Hengel, A.J., Roberts, J., Akiyama, H., Popping, B., Yeung, J.M., Wehling, P., Taylor, S.L., Poms, R.E., Delahaut, P.
Validation Procedures for Quantitative Food Allergen ELISA Methods: Community Guidance and Best Practices
J.AOAC Int., 93, 442-450 (2010)
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Akiyama, H., Sakata, K., Spiegelhalter, F., Furui, S., Nakashima, A., Kitta, K. , Teshima, R.
Interlaboratory Validation of an Event-Specific Real time Polymerase Chain Reaction Detection Method for Genetically Modified DAS59132 maize.
Food Hyg. Saf. Sci.(Shokuhin Eiseigaku Zasshi.), 51, 65-70 (2010)
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Mano, J., Yanaka, Y., Akiyama, H., Teshima, R., Furui, S., Kitta, K
Improvement of polymerase chain reaction-based Bt11 maize detection method by reduction of non-specific amplification
Food Hyg. Saf. Sci.(Shokuhin Eiseigaku Zasshi.), 51, 32-36 (2010)
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清木興介, 織田浩司, 柴原裕亮, 蒲生玲子, 有馬優美, 酒井信夫, 中村 厚, 安達玲子, 塩見一雄, 穐山 浩, 手島玲子
加工食品中の甲殻類タンパク質定量検査法における標準品調製法の検討
食品衛生学雑誌,51,133-138 (2010)
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Sakai, Y., Ishihata, K., Nakano, S., Yamada, T., Yano, T., Uchida, K., Nakao, Y., Urisu, A., Adachi, R., Teshima, R., Akiyama, H.
Specific detection of banana residue in processed foods using polymerase chain reaction
J Agric Food Chem., 58, 8145-8151 (2010)
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峰松和彦, 中村公亮, 穐山 浩, 張替直輝, 中島 治, 橘田和美, 手島玲子, 飯塚太由
コンニャク製粉含有コメ粉からのコメDNA抽出精製法の検討
食品衛生学雑誌, 51,247-252 (2010)
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Harikai, N., Akiyama, H., Kondo, K., Kitta, K., Teshima, R., Yoshida, Y.
A novel chromogenic method for determining the genetically modified soybean content in soybean powder with primer extension
Jpn. J. Food Chem. Safety, 17, 110-115 (2010)
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Takabatake, R., Onishi, M., Koiwa, T., Futo, S., Minegishi,Y., Akiyama, H., Teshima, R., Furui, S., Kitta, K.
Establishment and Evaluation of Event-Specific Quantitative PCR Method for Genetically Modified Soybean MON89788
Food Hygiene and Safety Science, 51, 242-246 (2010)
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Takabatake, R., Kodama, T., Matsuoka, T., Futo, S., Minegishi, Y., Watai, M., Sawada, C., Nakamura, K., Akiyama, H., Teshima, R., Furui, S., Akihiro, H., Kitta, K.
Evaluation of quantitative PCR methods for genetically modified maize (MON863, NK603, TC1507 and T25)
Food Sci. Technol. Res., 16, 421-430 (2010)
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Kodama, T., Kasahara, M., Minegishi, Y., Futo, S., Sawada, C., Watai, M., Akiyama, H., Teshima, R., Kurosawa, Y., Furui, S., Hino, A., Kitta, K.
Interlaboratory Study of Qualitative PCR Method for Roundup Ready Soybean
J AOAC Int. 94, 224-231 (2010)
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Akiyama, H., Makiyama, D, Nakamura, K., Sasaki, N., Minegishi, Y., Mano, J., Kitta, K., Ozeki, Y., Teshima R.
A Novel Detection System for the Genetically Modified Canola (Brassica rapa) Line RT73
Anal Chem., 82, 9909-9916 (2010)
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Nakamura, K., Fujioka, S., Fukumoto, S., Inoue, N., Sakamoto, K., Hirata, H., Kido, Y., Yabu, Y., Suzuki, T., Watanabe, Y., Saimoto, H., Akiyama, H., Kita, K.
Trypanosome alternative oxidase, a potential therapeutic target for sleeping sickness, is conserved among Trypanosoma brucei subspecies.
Parasitol. Int. 59, 560-564 (2010)
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Nakamura, K., Yamada, C., Akiyama, H., Takabatake, R., Kitagawa, M., Kitta, K., Kawakami, H., Teshima, R.
Evaluation of tomato DNA fragmentation and PCR amplicon size for detection of tomato DNA in processed products.
Jpn.J. of Food Chem. And Safety 17, 123-129 (2010)
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Sakai, S., Adachi, R., Akiyama, H., Teshima, R., Doi, H.,Shibata, H., Urisu, A.
Determination of Walnut Protein in Processed Foods by Enzyme-Linked Immunosorbent Assay: Interlaboratory Study.
J. AOAC Int., 93, 1255-1261 (2010)
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中村 厚, 酒井信夫, 川浦知子, 小林政人, 安達玲子, 穐山 浩, 手島玲子
すり身およびその加工食品中に自然混入する甲殻類の実態調査
日本食品化学学会誌,17,213-220 (2010)
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清水えり,布藤 聡,増淵友子,峯岸恭孝,日野明寛,穐山 浩,手島玲子,古井 聡,橘田和美
ポリプロピレン製品 DNA 検査に及ぼす影響 : PCR 検査に好適なマイクロチューブの選択方法について
食品衛生学雑誌,51, 43-47(2010)
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Satoh R., Koyano S., Takagi K., Nakamura R., Teshima R.
Identification of an IgE-Binding Epitope of a Major Buckwheat Allergen, BWp16, by SPOTs Assay and Mimotope Screening.
Int. Arch. Allergy Immunol. 153(2), 133-140 (2010)
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Asakawa N., Sakiyama N., Teshima R..,Mitaku S.
Characteristic amino acid distribution around segments unique to allergens.
J. Biochem. 147, 127-133 (2010)
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Nakamura, R., Nakamura, R., Nakano, M., Arisawa, K., Ezaki, R., Horiuchi, H. and Teshima, R.
Allergenicity study of EGFP-transgenic chicken meat by serological and 2D-DIGE analysis.
Food Chem. Toxicol., 48, 1302-10 (2010).
-
Sakai, S., Adachi, R.,Akiyama, H.,Teshima,R., Morishita, N.,Matsumoto, T.,Urisu, A.
Enzyme-linked immunosorbent assay kit for the determination of soybean protein in processed foods: interlaboratory evaluation.
J. AOAC Int., 93, 243-248 (2010)
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Kondo, K., Obitsu, S., Ohta, S., Matsunami, K., Otsuka, H., Teshima, R.
Poly(ADP-ribose) polymerase (PARP)-1- independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha- tocopherol and MEK inhibition.
J. Biol. Chem., 285, 13079-13091 (2010)
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Mano, J., Yanaka, Y., Akiyama, H., Teshima, R., Furui, S., Kitta, K.
Improvement of polymerase chain reaction-based BT11 maize detection method by reduction of non-specific amplification.
Shokuhin Eiseigaku Zasshi. 51, 32-36 (2010)
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Nakamura, K., Akiyama, H., Yamada, C., Satoh, R., Makiyama, D., Sakata, K., Kawakami, H., Mano, J., Kitta, K., Teshima R.
Novel method to detect a construct-specific sequence of the acetolactate synthase gene in genetically-modified flax CDC Triffid (FP967).
Biol. Pharm. Bull. 33, 532-534 (2010)
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酒井信夫, 安達玲子,中村 厚,柴原裕亮,上坂良彦,清木興介,織田浩司,穐山 浩,手島玲子
いわゆる健康食品に含まれる甲殻類様タンパク質量の実態調査.
日本食品化学学会誌, 16, 118-122 (2009)
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穐山 浩,佐々木伸大,大木果林,中村文美,坂田こずえ,中村公亮,大森清美,中島安基江,古井 聡,橘田和美,小関良宏,手島玲子
PCR法を用いた米加工品の安全性未審査遺伝子組換え米の検知法
日本食品化学会誌,16, 147-151 (2009)
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橋本博之,伊藤 歌奈子,田中裕之,穐山 浩,手島玲子,眞壁裕樹,中西希代子,宮本文夫
モデル加工食品を用いた特定原材料(小麦)検査におけるネステッド PCR 法の検討
食品衛生学雑誌,50, 178-183 (2009)
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Kezuka Y., Itagaki T., Satoh R., Teshima R., Nonaka T.
Purification, crystallization and preliminary X-ray analysis of a deletion mutant of a major buckwheat allergen.
Acta Cryst. F65, 1267-1270 (2009)
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Nakamura, R. Satoh, R., Nakajima, Y., Kawasaki, N., Yamaguchi, T., Sawada, J., Nagoya, H. and Teshima, R.
Comparative study of GH-transgenic and non-transgenic amago salmon (Oncorhynchus masou ishikawae) allergenicity and proteomic analysis of amago salmon allergens.
Regul. Toxicol. Pharmacol., 55, 300-8 (2009).
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Nakamura, R., Uchida, Y., Higuchi, M. and Teshima, R.
Development of a novel allergy test using a cultured mast cell line.
ImmunoTox Lett., 14, 12-13 (2009)
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Nakamura, R., Nakamura, R. and Teshima, R.
Major revision of the allergen database for food safety (ADFS) and validation of the motif-based allergenicity prediction tool.
Bull. Natl. Inst. Health Sci., 127, 44-49 (2009)
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Nakajima, O., Akiyama, H., Teshima, R.
Real-Time PCR Method for Detecting Contamination of Beef by Material from Genetically Engineered Cattle.
Biol. Pharm. Bull., 32, 1313-1316 (2009)
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Oguchi, T., Onishi, M., Chikagawa, Y., Kodama, T., Suzuki, E., Kasahara, M., Akiyama, H., Teshima, R., Futo, S., Hino, A., Furui, S., Kitta, K.
Investigation of residual DNAs in sugar from sugar beet (Beta vulgaris L.).
Shokuhin Eiseigaku Zasshi. 50, 41-46 (2009)
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Oguchi, T., Onishi, M., Minegishi, Y., Kurosawa, Y., Kasahara, M., Akiyama, H., Teshima, R., Futo, S., Furui, S., Hino, A., Kitta. K.
Development of quantitative duplex real-time PCR method for screening analysis of genetically modified maize.
Shokuhin Eiseigaku Zasshi. 50, 117-125 (2009)
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Ohgiya Y, Arakawa F, Akiyama H, Yoshioka Y, Hayashi Y, Sakai S, Ito S, Yamakawa Y, Ohgiya S, Ikezawa Z, Teshima R.
Molecular cloning, expression, and characterization of a major 38-kd cochineal allergen.
J Allergy Clin Immunol. 123, 1157-1162 (2009)
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Suzuki, Y., Kassai, M., Hirose, T., Katayama, S., Nakamura, K., Akiyama, H., Teshima, R., Nakamura, S.
Modulation of Immunoresponse in BALB/c Mice by Oral Administration of Fag e 1-Glucomannan Conjugate.
J. Agric. Food Chem. 57, 9787–9792 (2009)
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Harikai, N., Saito, S., Abe, M., Kondo, K., Kitta, K., Akiyama, H., Teshima, R., Kinoshita, K.
Optical detection of specific genes for genetically modified soybean and maize using multiplex PCR coupled with primer extension on a plastic plate.
Biosci. Biotechnol. Biochem. 73, 1886-1889 (2009)
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Akiyama, H., Nakamura, F., Yamada, C., Nakamura, K.,Nakajima, O., Kawakami, H., Harikai, N., Furui, S., Kitta, K., Teshima R.
A screening method for the detection of the 35S promoter and the nopaline synthase terminator in genetically modified organisms in a real-time multiplex polymerase chain reaction using high-resolution melting-curve analysis.
Biol. Pharm. Bull. 32, 1824-1829 (2009)
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Mano, J., Oguchi, T., Akiyama, H., Teshima, R., Hino, A., Furui, S., Kitta K.
Simultaneous Detection of Recombinant DNA Segments Introduced into Genetically Modified Crops with Multiplex Ligase Chain Reaction Coupled with Multiplex Polymerase Chain Reaction.
J. Agric. Food Chem., 57, 2640-2646 (2009)
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Mano, J., Shigemitsu, N., Futo, S., Akiyama, H., Teshima, R., Hino, A., Furui, S., Kitta K.
Real-time PCR array as a universal platform for the detection of genetically modified crops and its application in identifying unapproved genetically modified crops in Japan.
J. Agric. Food Chem., 57, 26-37 (2009)
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Oguchi,T., Onishi,M., Chikagawa, Y., Kodama,T., Suzuki, E., Kasahara, M., Akiyama, H., Teshima, R., Futo, S., Hino, A., Furui, S., Kitta, K.
Investigation of Residual DNAs in Sugar from Sugar Beet (Beta vulgaris L.).
J. Food Hyg. Soc. Japan, 50, 41-46 (2009)
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Kodama, T., Kuribara, H., Minegishi, Y., Futo, S., Watai, M., Sawada, C., Watanabe, T., Akiyama, H., Maitani T, Teshima R, Furui, S., Hino, A., Kitta, K.
Evaluation of Modified Quantitation of Genetically Modified Maize and Soybean Using Reference Molecules: Interlaboratory Study.
J AOAC Int. 92, 223-233 (2009)
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Toida, T., Sato, K., Sakamoto, N., Sakai, S., Hosoyama, S., Linhardt, R. J.
Solvolytic depolymerization of chondroitin and dermatan sulfates.
Carbohydr. Res., 344, 888-893 (2009)
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Satoh, R., Koyano, S., Takagi, K., Nakamura, R, Teshima, R., Sawada, J.
Immunological Characterization and mutational analysis of the recombinant protein BWp16, a major allergen buckwheat.
Biol.Pharm. Bull. 31, 1079-1085 (2008)
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Teshima, R., Nakamura, R., Nakamura, R., Hachisuka, A., Sawada, J., Shibutani, M.
Effects of Exposure to Decabromodiphenyl Ether on the Development of the Immune System in Rats.
J.Health Sci., 54(4), 382-389 (2008)
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Nakamura, R., Hachisuka, A., Sato, Y., Nakamura, R., Shibutani, M.*1, Sawada, J., Teshima, R.
Effect of perinatal exposure to the flame-retardant tetrabromobisphenol A on the developing immune system of rats.
Bulletin of National Institute of Health Sciences, 126, 65-70 (2008)
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Yoshioka, Y., Akiyama, H., Nakano, M., Shoji, T., Kanda, T., Ohtake, Y., Takita, T., Matsuda, R., Maitani, T.
Orally administered apple procyanidins protect against experimental inflammatory bowel disease in mice.
Int Immunopharmacol. 20, 1802-1807 (2008)
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Shimizu, E.., Kato, H., Nakagawa, Y., Kodama, T., Futo, S.,Minegishi, Y., Watanabe, T., Akiyama, H., Teshima, R., Furui, S., Hino, A., Kitta, K.
Development of a screening method for genetically modified soybean by plasmid-based quantitative competitive polymerase chain reaction.
J. Agric. Food Chem. 56, 5521-5527 (2008)
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Yamakawa, H., Akiyama, H., Endo, Y., Miyatake, K., Sakata, K., Sakai, S., Toyoda, M., Urisu, A., Teshima, R.
Specific Detection of Buckwheat Residues in Processed Foods by Polymerase Chain Reaction
Biosci. Biotech. Biochem., 72, 2228-2231 (2008)
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Morishita, N., Kamiya, K., Matsumoto, T., Sakai, S., Teshima, R., Urisu, A., Moriyama, T., Ogawa, T., Akiyama, H., Morimatsu, F.
Reliable Enzyme-Linked Immunosorbent Assay for the Determination of Soybean Proteins in Processed Foods .
J. Agric. Food Chem. 56, 6818-6824 (2008)
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Doi, H., Touhata Y.,Shibata, H., Shoji, M., Sakai, S., Urisu, A., Akiyama, H., Teshima, R.
Reliable Enzyme-Linked Immunosorbent Assay for the Determination of Walnut Proteins in Processed Foods.
J. Agric. Food Chem. 56, 7625-7630 (2008)
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Harikai, N., Saito, S., Abe, M., Kondo, K., Kitta, K., Akiyama, H., Teshima, R., Kinoshita, K.
Real-Time PCR Method Using Capturing Oligo-Immobilized PCR Tubes to Determine the Specific Gene for Soybean and Genetically Modified Soybean in Food Matrices.
Biosci. Biotech. Biochem., 72, 2953-2958 (2008)
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Akiyama, H., Sakata K., Kondo K., Tanaka A., Liu S. M., Oguchi, T., Furui, S., Kitta, K., Hino, A. and Teshima, R.
Individual Detection of Genetically Modified Maize Varieties in Non-Identity-Preserved Maize Samples
J. Agric. Food Chem., 56, 1977-1983 (2008)
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Oguchi, T., Onishi, M., Chikagawa, Y., Minegishi, Y., Kodama, T., Akiyama, H., Ohno, Y., Futo, S., Hino, A., Furui, S. and Kitta, K.
Development of Event-Specific Quantitation Method for GA21 Maize,Which Is a GM Event without CaMV35S Promoter
J. Food Hyg. Soc. Japan., 49, 16-22 (2008)
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大森清美,土屋久世,渡邉敬浩,穐山浩,米谷民雄,山田利治,伊藤伸一,佐藤修二
トウモロコシ加工食品からのイオン交換タイプキットを用いたDNA抽出精製法の検討
J. Food Hyg. Soc. Japan., 49, 45-50 (2008)
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Sakai, S., Matsuda, R., Adachi, R., Akiyama, H., Maitani, T., Ohno, Y., Oka, M., Abe, A., Seiki, K., Oda, H., Shiomi, K. and Urisu, A.
Interlaboratory evaluation of two enzyme-linked immunosorbent assay (ELISA) kits for the determination of crustacean protein in processed foods.
J. AOAC Int., 91, 123-129 (2008)
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酒井信夫,安達玲子,柴原裕亮,岡道弘,阿部晃久,清木興介,織田浩司,吉岡久史,塩見一雄,宇理須厚雄,穐山浩,手島玲子
食品原材料中に含まれる「えび」、「かに」等の甲殻類タンパク質の実態調査
日本食品化学学会誌, 15, 1-6 (2008)
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Amano, H., Negishi, I., Akiyama, H. and Ishikawa, O.
Psychological stress can trigger atopic dermatitis in NC/Nga mice: an inhibitory effect of corticotropin-releasing factor
Neuropsychopharmacology. 33(3):566-73 (2008)
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Kondo K, Watanabe A, Akiyama H, Maitani T.
The metabolisms of agaritine, a mushroom hydrazine in mice
Food and Chem. Toxicol..46,854 (2008)
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酒井信夫, 松田りえ子, 杉本敏明, 米谷民雄
野菜及び野菜加工食品に含まれる硝酸塩について.
日本食品化学学会誌, 15, 110-115 (2008)
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Suzuki R, Furuno T, Okamoto K, Teshima R, Nakanishi M.
ATP plays a role in neurite stimulation with activated mast cells.
J. Neuroimmunol, 192, 49-56 (2007)
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Nakamura, R., Teshima, R., Hachisuka, A., Sato, Y., Takagi, K., Nakamura, R., Woo, G.H., Shibutani, M., Sawada, J.
Effects of developmental hypothyroidism induced by maternal administration of methimazole or propylthiouracil on the immune system of rats
Int. Immunopharmacol., 7, 1630-1638 (2007)
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Yamakawa, H., Akiyama, H., Endo, Y., Miyatake, K., Sakata, K., Sakai, S., Toyoda, M. and Urisu, A.
A Specific Detection of Wheat Residues in Processed Foods Using Polymerase Chain Reaction
Biosci. Biotech. Biochem., 71, 2561-2564 (2007)
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Yano, T., Sakai, Y., Uchida, K., Nakao, Y., Ishihata, K., Nakano, S., Yamada, T., Sakai, S., Urisu, A., Akiyama, H. and Maitani, T.
Detection of Walnut Residues in Processed Foods by Polymerase Chain Reaction
Biosci. Biotech. Biochem., 71, 1793-1796 (2007)
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Akiyama, H., Sasaki N., Sakata K., Ohmori K., Toyota A., Kikuchi, Y., Watanabe, T., Furui, S., Kitta, K. and Maitani, T.
Identification and detection of GM Shanyou 63 line and unknown Bt rice line contaminating rice vermicelli products
J. Agric. Food Chem., 55, 5942-5947 (2007)
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Seiki, K., Oda, H., Yoshioka, H., Sakai, S., Urisu, A., Akiyama, H. and Ohno, Y.
A Reliable and Sensitive Immunoassay for the Determination of Crustacean Protein in Processed Foods
J.Agric. Food Chem., 55, 9345-9350 (2007)
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Tanabe, S., Hase, M., Yano, T., Sato, M., Fujimura, T. and Akiyama, H.
Real-Time Quantitative PCR Detection Method for Pork, Chicken, Beef, Mutton, and Horseflesh in Foods
Biosci. Biotech. Biochem., 71, 3131-3135 (2007)
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森山達哉,光山英由,矢野えりか,大羽美香,橘田和美,川本伸一,穐山浩,宇理須厚雄,高橋浩司,羽鹿牧太,小川正,河村幸雄
食物アレルゲンタンパク質の近赤外蛍光標識プローブによる検出
日本食品科学工学会誌, 54, 468-476 (2007)
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Amano, H., Akiyama, H. and Bienenstock, J.
Differential corticosterone responses to stress in the lung in two strains of Flinders rats
Clin. Exp Allergy, 38, 659-666 (2007)
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Sakai, S., Hirano, K., Toyoda, H., Linhardt, R. J. and Toida, T.
Matrix assisted laser desorption ionization-time of flight mass spectrometry analysis of hyaluronan oligosaccharides.
Anal. Chim. Acta., 593, 207-213 (2007)
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Kusano, S., Ootani, A., Sakai, S., Igarashi, N., Takeguchi, A., Toyoda, H. and Toida, T.
HPLC determination of chondrosine in mouse blood plasma after intravenous or oral dose.
Biol. Pharm. Bull., 30, 1365-1368 (2007)
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Ohtsuki, T., Yokosawa, E., Koyano, T., Preeprame, S., Kowithayakorn, T., Sakai, S., Toida, T. and Ishibashi, M.
Quinic acid esters from Pluchea indica with collagenase, MMP-2 and MMP-9 inhibitory activities.
Phytother. Res., 22, 264-266 (2007)
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Taguchi H, Watanabe S, Hirao T, Akiyama H, Sakai S, Watanabe T, Matsuda R, Urisu A, Maitani T.
Specific detection of potentially allergenic kiwifruit in foods using polymerase chain reaction
J. Agric Food Chem., 55, 1649-1655 (2006)
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Akiyama, H., Sakata, K., Yoshioka, Y., Murata, Y., Ishihara, Y., Teshima, R., Sawada J., Maitani, T.
Profile analysis and allergenecity of wheat protein hydorolysates
Int. Arch. Allergy Immnol., 140, 36-42 (2006)
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Kondo K, Watanabe A, Iwanaga Y, Abe I, Tanaka H, Nagaoka MH, Akiyama H, Maitani T.
alysis of agaritine in mushrooms and in agaritine-administered mice using liquid chromatography-tandem mass spectrometry.
J. Chromatogr B.834, 55-61 (2006)
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Kondo K, Watanabe A, Iwanaga Y, Abe I, Tanaka H, Nagaoka MH, Akiyama H, Maitani T
Determination of genotoxic phenylhydrazine agaritine in mushrooms using liquid chromatography-electrospray ionization tandem mass spectrometry.
Food Additive Contaminants 23, 1179-1186 (2006)
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Amakura, Kondo, K., Akiyama, H., Ito, H., Hatano, T., Yoshida, T., and Maitani, T.
Conjugated ketonic fatty acids from Pleurocybella porrigens.
Chem. Pharm. Bull. 54,1213-1215 (2006)
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Sasaki, H., Akiyama, H., Yoshida, Y., Kondo, K., Amakura,Y., Kasahara, Y., and Maitani, T.
Sugihiratake mushroom (angel's wing mushroom)-induced cryptogenic encephalopathy may involve vitamin D analogues.
Biol. Pharm. Bull. 29, 2514-2518 (2006)
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Toyota, A., Akiyama, H., Sugimura, M., Watanabe, T., Kikuchi, H., Kanamori, H., Hino, A., Esaka, M., Maitani, T.
Quantification of genetically modified soybeans using the combination of a capillary-type real-time PCR system and a plasmid reference standard
Biosci. Biotech. Biochem., 70, 821-827 (2006)
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Sakai, S., Akiyama, H., Sato, Y., Yoshioka, Y., Linhardt, RJ., Goda, Y., Maitani, T., Toida T.
Chondroitin sulfate intake inhibits the IgE-mediated allergic response by down-regulating Th2 responses in mice
J. Biol. Chem., 281, 19872-19880 (2006)
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Shoji, T., Masumoto, S., Moriichi, N., Akiyama, H., Kanda, T., Ohtake, Y., Goda Y.
Apple Procyanidin Oligomers Absorption in Rats After Oral Administration: Analysis of Procyanidins in Plasma Using the Porter Method and HPLC/MS/MS
J. Agric. Food Chem., 54, 884-892 (2006)
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Akiyama, H., Watanabe, T., Wakabayashi, K., Nakade, S., Yasui, S., Sakata, K., Chiba, R., Spiegelhalter, F., Hino, A., Maitani, T.
A Novel Quantitative Detection System for Maize Sample Containing Combined-Trait Genetically Modified Maize
Anal. Chem., 77, 7421-7428 (2005)
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Onishi, M., Matsuoka, T., Kodama, T Kashiwaba, K., Futo, S., Akiyama, H., Maitani, T., Furui, S., Oguchi, T., Hino, A.
Development of a Multiplex PCR Method for Simultaneous Detection of Eight Events of Genetically Modified Maize
J. Agric. Food Chem. 53, 9713-9721 (2005)
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Iida, M., Yamashiro, S., Yamakawa, H., Hayakawa, K., Kuribara, H., Kodama, T., Furui, S., Akiyama, H., Maitani, T. Hino, A.
Developments of taxon-specific sequences of common wheat for the detection methods of GM wheat
J. Agric. Food Chem. 53, 6294-6300 (2005)
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Yoshimura, T., Kuribara, H., Matsuoka, T., Kodama, T., Shigematsu, M., Watanabe, T., Akiyama, H., Maitani, T., Furui, S., Hino, A.
Applicability of the Quantification of Genetically Modified Organisms to Foods Processed from Maize and Soy,
J. Agric. Food Chem. 53, 2052-2059 (2005)
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Akiyama H, Amano H, Bienenstock J
Rat tracheal epithelial responses to water avoidance stress
J. Allergy Clin. Immunol. 116, 318-324 (2005)
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Akiyama, H., Sato, Y., Watanabe, T., Nagaoka, MH., Yoshioka, Y., Shoji, T., Kanda, T., Yamada, K., Totsuka, M., Teshima, R., Goda, Y., Sawada, J., Maitani, T.
Dietary unripe apple polyphenol inhibits the development of food allergy in murine models
FEBS letters, 579, 4485-4491 (2005)
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Watanabe, T., Kuribara, H., Mishima, T., Kikuchi, H., Kubo, M., Kodama, T., Futo, S., Kasama, K., Toyota, A., Nouno, M., Saita, A., Takahashi, K., Hino, A., Akiyama, H., Maitani T.
New qualitative detection methods of genetically modified potatoes
Biol. Pharm Bull., 27, 1333-1339 (2004)
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Akiyama, H., Sakai, S., Linhardt, RJ., Goda, Y., Toida, T., Maitani, T.
Chondroitin sulphate structure affects its immunological activities on murine splenocytes sensitized with ovalbumin
Biochem. J., 382, 269?278 (2004)
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Sato, Y., Akiyama, H., Suganuma, H., Watanabe, T., Nagaoka, MH., Inakuma, T., Goda, Y., Maitani, T.
The feeding of β-carotene down-regulates serum IgE levels and inhibits the type I allergic response in mice
Biol. Pharm. Bull., 27, 978-984 (2004)