What's new
- 2024.04.01
- Division of Genome Safety Science was established with organizational reform. This webpage will be updated soon.
- 2024.01.23
- The 2nd AMES/QSAR International Challenge Project updated
- 2023.12.05
- The 2nd AMES/QSAR International Challenge Project publication updated
- 2023.08.01
- Recent Publications updated
- 2022.08.01
- Recent Publications updated
- 2021.08.16
- Recent Publications updated
- 2020.08.03
- Recent Publications updated
- 2019.08.05
- ICH-M7 in silico Workshop updated
- 2019.07.05
- Ames/QSAR updated
- Science for Genome Safety updated
- 2018.12.21
- TK6 Mutants Consortium updated
- 2018.11.13
- Recent Publications updated
- 2018.05.08
- AMES/QSAR International Collaborative Study updated
- 2018.05.08
- ICH-M7 in silico Workshop updated
- 2017.07.21
- AMES/QSAR International Collaborative Study updated
- 2017.02.27
- ICH-M7 in silico Workshop launched!
- 2017.02.08
- TK6 Mutants Consortium launched!
- 2016.10.25
- AMES/QSAR International Collaborative Study updated
- 2015.11.20
- AMES/QSAR International Collaborative Study launched!
- 2015.11.19
- New tab, Resources, open
- 2015.09.14
- Recent Publications updated
- 2015.01.20
- Recent Publications updated
- 2014.07.01
- Research Activities updated
- 2014.01.15
- Recent Publications updated
- 2013.09.27
- Other Publications (1970s~2012) updated
- 2013.06.17
- Recent Publications updated
- 2013.04.15
- Homepage renewal
About us
Many chemical substances exist in our living environment, and the number is increasing every year. Some classes of chemical substances affect a gene causing cancers and hereditary diseases which are so-called "Genotoxic Chemicals".
The mission of Division of Genome Safety Science is to identify genotoxic chemicals, i.e., hazard identification, and evaluate the risk to humans, i.e., risk assessment, and remove or reduce them from our environment through administrative regulations, if necessary, thereby assuring the integrity of human genome. To accomplish the mission, we are engaged in;
(1) Development of various genotoxicity assays, i.e., in silico, in vitro and in vivo, and harmonization of international guidelines for the assays.
(2) Research on mechanisms of mutagenesis and DNA repair and application of the basic knowledge to risk assessment of chemicals.
(3) Regulation of chemicals through participation in administrative committees in regulatory agencies.