Science for Genome Safety

What's new

2017.07.21
AMES/QSAR International Collaborative Study updated
2017.02.27
ICH-M7 in silico Workshop launched!
2017.02.08
TK6 Mutants Consortium launched!
2016.10.25
AMES/QSAR International Collaborative Study updated
2015.11.20
AMES/QSAR International Collaborative Study launched!
2015.11.19
New tab, Resources, open
2015.09.14
Recent Publications updated
2015.01.20
Recent Publications updated
2014.07.01
Research Activities updated
2014.01.15
Recent Publications updated
2013.09.27
Other Publications (1970s~2012) updated
2013.06.17
Recent Publications updated
2013.04.15
Homepage renewal

About us

Many chemical substances exist in our living environment, and the number is increasing every year. Some classes of chemical substances affect a gene causing cancers and hereditary diseases which are so-called "Genotoxic Chemicals".
The mission of Division of Genetics and Mutagenesis is to identify genotoxic chemicals, i.e., hazard identification, and evaluate the risk to humans, i.e., risk assessment, and remove or reduce them from our environment through administrative regulations, if necessary, thereby assuring the integrity of human genome. To accomplish the mission, we are engaged in;
(1) Development of various genotoxicity assays, i.e., in silico, in vitro and in vivo, and harmonization of international guidelines for the assays.
(2) Research on mechanisms of mutagenesis and DNA repair and application of the basic knowledge to risk assessment of chemicals.
(3) Regulation of chemicals through participation in administrative committees in regulatory agencies.