The division conducts a variety of in vivo bioassays on drugs, pesticides, food additives and environmental chemicals to assess their safety to humans by analyzing histopathology and other toxicological endpoint markers. We also investigate the molecular mechanisms underlying chemically-induced toxicological/neoplastic lesions, the modifying factors on carcinogenesis, and the new bioassay systems, consequently providing basic data closely-linked to human health.

Conference aimed at discussing hitopathological diagnosis

Collection of specific regions by microdissection for gene expression analysis

HE staining (left) and immunohistochemical demonstration of GSTP-positive liver cells (right)

Preparation of tissue slides from the block embedded in paraffin

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