DIVISION OF ORGANIC CHEMISTORY

The division consists of two sections engaged in organic chemistry research on chemical substances with regard to molecular structure, reactivity and structure-reactivity relationships to clarify the efficacy and safety of pharmaceutical substances and other chemicals. It is also involved in synthesis of physiologically active new chemicals, determination of their reactivity, and investigation of interactions between chemicals and biomolecules using physico-chemical methods and computer calculation.

Computer-modeling of interaction between chemical and receptor protein The modeling provides important information for design of highly active new chemicals.

Series of pharmaceutical substances are synthesized to allow investigation of their reactivities.

Synthetic routes of chemicals are optimized using a computer search system.

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