The major mission of this division is to investigate the effect of drugs and chemicals on biological functions. Currently, research activities focus on molecular mechanism of cell death, molecular function of anti-apoptotic proteins, cell cycle regulation, drug development for molecular target therapy, prediction of the drug response with genomic information, transcriptional and post-transcriptional regulation of lipid transporters, and functional regulation of nuclear receptors.

Pharmacogenetic study has led to realization of "Personalized Therapy" of an anti-cancer drug, irinotecan.

Electron micrographs of apoptotic and necrotic leukemia cells treated with anti-cancer drugs.

Investigating the influence of chemicals on nuclear receptor functions closely associated with metabolic diseases.

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