$B4D6-J]7r%/%i%$%F%j%"!!(B92
Environmental Health Criteria$B!!(B92

$B%l%9%a%H%j%s!!!!(BResmethrin
($B9g@.%T%l%9%m%$%I7O;&Cn:^(B)

($B86Cx(B79$BJG(B, 1990$BG/H/9T(B)

-$BL\
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1.$BMWLs$*$h$SI>2A(B
2.$B7k!!!!!!O@(B
3.$B4+!!!!!!9p(B
4.$B9q:]5!4X$K$h$k$3$l$^$G$NI>2A(B

$B$O$8$a$K!!(B-$B9g@.%T%l%9%m%$%I$N35@b(B-

1. $BE7A3$N%T%l%H%j%s$N2=3X9=B$$r2~JQ$9$k8&5f$rDL$7$F!"J*M}E*$*$h$S2=3XE*FC@-$,2~A1$5$l!"$h$j6/NO$J@8J*3XE*3h@-$rM-$9$k?t!9$N9g@.%T%l%9%m%$%I$,@=B$$5$l$?!#=i4|$N9g@.%T%l%9%m%$%I$N$&$A$$$/$D$+$O>&IJ2=$K@.8y$7!"$N$h$j:G6a3+H/$5$l$?%T%l%9%m%$%I$O!"9-HO0O$N32Cn$KBP$9$kM%$l$?8z2L$H!"4D6-Cf$G$N;DN1@-$,Dc$$$3$H$+$iG@6HMQ$N;&Cn:^$H$7$FF3F~$5$l$F$-$?!#(B
2. $B%T%l%9%m%$%I$O!"M-5!1vAG!"M-5!%j%s!"%+!<%P%a!<%H!"$=$NB>$N2=9gJ*$K2C$($F!"JL$N;&Cn:^$N%0%k!<%W$r9=@.$9$k!#8=:_>&IJ2=$5$l$F$$$k%T%l%9%m%$%I$H$7$F!"%"%l%9%j%s!"%l%9%a%H%j%s!"(Bd-$B%U%'%N%H%j%s!"%F%H%i%a%H%j%s(B($B8x=01R@8>e=EMW$J32CnMQ(B)$B$*$h$S%7%Z%k%a%H%j%s!"%G%k%?%a%H%j%s!"%U%'%s%P%l%l!<%H!"%Z%k%a%H%j%s(B($Bo$O2HDm32CnMQ(B)$B!"%U%'%s%W%m%Q%H%j%s!"%H%i%m%a%H%j%s!"%7%O%m%H%j%s!"%i%`%@(B-$B%7%O%m%H%j%s!"%F%U%k%H%j%s!"%7%U%k%H%j%s!"%U%k%7%H%j%M!<%H!"%U%k%P%j%M!<%H!"%P%$%U%'%M!<%H(B(biphenate)($BG@6H32CnMQ(B)$B$,4^$^$l$k!#(B
3. $B$$$/$D$+$N9g@.%T%l%9%m%$%I$NFG@-3XE*I>2A$O!"?)NHG@6H5!4X(B(FAO)/$B@$3&J]7r5!4X(B(WHO)$B$N9gF1$N;DN1G@Lt@lLg2H2q5D(B(JMPR)$B$K$h$j9T$o$l$F$$$k!#%7%Z%k%a%H%j%s!"%G%k%?%a%H%j%s!"%U%'%s%P%l%l!<%H!"%Z%k%a%H%j%s!"(Bd-$B%U%'%N%H%j%s!"%7%U%k%H%j%s!"%7%O%m%H%j%s!"%U%k%7%H%j%M!<%H$N0lF|5vMF@]
4. $B9g@.%T%l%9%m%$%I$O!"2=3XE*$K$OFCDj$N;@(B($BNc$($P!"5F;@!"%O%m%2%sCV49$N5F;@!"(B2-(4-$B%/%m%m%U%'%K%k(B)-3-$B%a%A%kMo;@(B)$B$H%"%k%3!<%k(B($BNc$($P!"%"%l%9%m%m%s!"(B3-$B%U%'%N%-%7%Y%s%8%k%"%k%3!<%k(B)$B$N%(%9%F%k$G$"$k!#$"$kd/l)$B$*$h$S4v2?(B(cis/trans)$BAPJ}$N0[@-BN$N:.9gJ*$+$i9=@.$5$l$F$$$k!#$7$+$7!"$=$l$i$N@=IJ$N;&Cn:nMQ$NBgItJ,$O(B1$B
5. $B9g@.%T%l%9%m%$%I$O!"S.F}N`$*$h$S(B/$B$^$?$O:+CnN`$N%J%H%j%&%`%A%c%M%k$r:nMQE@$H$7$F!"Kv>?$*$h$SCf?u?@7P7O$N<4:w$K:nMQ$9$k?@7PFG$G$"$k!#C12sEjM?$K$h$j!"S.F}N`$G$O!"?6@o(B($B$U$k$((B)$B!"0[>o6=J3!"N.^7!"IqF'IBMM%"%F%H!<%7%9(B($BLuI$H$b$$$$!";X$do$KO"B3$7$F$$$k>uBV(B)$B!"Kcac$J$I$NFG@-D'8u$r@8$8$5$;$?!#$3$ND'8u$O$+$J$jB.$d$+$K>C<:$7!"F0J*$O0lHLE*$K$O0l=54V0JFb$K2sI|$9$k!#9g@.%T%l%9%m%$%I$O!"CW;`NL$K6a$$EjM?NL$G$O!"<4:w$NI$5$;$k!"$H$O8+$J$5$l$F$$$J$$!#9g@.%T%l%9%m%$%I$NFG@-%a%+%K%:%`$H!"$=$l$i$N(B2$B
6. $B0lIt$N%T%l%9%m%$%I(B($B%G%k%?%a%H%j%s!"%U%'%s%P%l%l!<%H!"%7%O%m%H%j%s!"%i%`%@(B-$B%7%O%m%H%j%s!"%U%k%7%H%j%M!<%H!"%7%Z%k%a%H%j%s(B)$B$OK=O*$5$l$?%R%H$NHiIf$K0l2a@-$N$+$f$_$*$h$S(B/$B$^$?$O<^G.46$r@8$8$5$;$k!#(B
7. $B9g@.%T%l%9%m%$%I$O!"0lHL$K$O!"S.F}N`$K$*$$$F$O!"%(%9%F%k2C?eJ,2r!";@2=:nMQ!"Jz9g$K$h$jBem!"?"J*Cf$G$+$J$jB.$d$+$KJ,2r$5$l$k!#%(%9%F%k2C?eJ,2r$HJ,;R$Nm$*$h$SDl
8. $B;\MQG;EY$NDc$$$3$H$H4D6-Cf$G$NB.$d$+$JJ,2r$K$h$j!"?)IJCf$N;DN1$O0lHLE*$K$ODc$$!#(B
9. $B9g@.%T%l%9%m%$%I$O!"
10. FAO/WHO$B$NI>2A;qNA$N$[$+!"9g@.%T%l%9%m%$%IN`$N2=3XE*FC@-!"Be$K$D$$$F!"$$$/$D$+$NM%$l$?%l%S%e!<$H@.=q$,4)9T$5$l$F$*$j!"$3$l$i$K$O!"(BElliot(1977)$B!"(BMiyamoto(1981)$B!"(BMiyamoto & Kearney(1983)$B!"(BLeahey(1985)$B$,4^$^$l$k!#(B
($BLu>N$N$&$A!"F|K\$GG@LtEPO?$N$J$$;&Cn:^(B(kadethrin$B!"(Btellallethrin$B!"(Bbiphenate)$B$K$O1Q8l86L>$rIU5-$7$?!#(B)




1.$BMWLs$*$h$SI>2A(B

1.1$B!!J*

$B%l%9%a%H%j%s$O!":G=i$K(B1967$BG/$K@=B$$5$l!"(B1969$BG/$K=i$a$F;T>l$GHNGd$5$l$?!#2=3XE*$K$O!"5F;@(B(2,2-$B%8%a%A%k(B-3-(2,2-$B%8%a%A%k%S%K%k(B)$B%7%/%m%W%m%Q%s%+%k%\%s;@(B)$B$H(B5-$B%Y%s%8%k(B-3$B%U%j%k%a%A%k%"%k%3!<%k(B(BFA)$B$N%(%9%F%k$G$"$k!#$=$l$O!"(B4$Btrans]-$B!"(B[1R, cis]-$B!"(B[1S, trans]-$B!"(B[1S, cis]-$B0[@-BN$N%i%;%_:.9gJ*$G$"$k!#9)6H@=IJ86BN$K$*$$$F$O!"$=$N9=@.Hf$O$[$\(B4:1:4:1$B$G$"$k!#(B[1R, trans]$B0[@-BN$O%P%$%*%l%9%a%H%j%s!"(B[1R, cis]$B0[@-BN$O%7%9%a%H%j%s$H8F$P$l$k!#$3$l$i$N0[@-BNCf$G!"(B[1R, trans]$B0[@-BN$,:G$b9b$$@8J*3XE*3h@-$rM-$7!"cis]$B0[@-BN$G$"$k!#(B

$B9)6H@=IJ86BN$N%l%9%a%H%j%s$O!"(B0.01mmHg$B$K$*$$$F!"M;E@(B43$B!A(B48$B!n!"J(E@(B180$B!n$NL5?'$N%o%C%/%9>u$N8GBN$G$"$k!#Hf=E$O(B20$B!n$K$*$$$F(B1.050$B!">x5$05$O(B30$B!n$K$*$$$F(B1.1$B!_(B10-8mmHg$B$G$"$k!#?e$KITMO@-(B(30$B!n$K$*$$$F(B1mg/l$B0J2<(B)$B$G$"$k$,!"%X%-%5%s!&%1%m%7%s!&%-%7%l%s$J$I$NM-5!MO:^$K$OMO2r$9$k!#$^$?!"6u5$Cf!"8w!"%"%k%+%j>r7o2<$G$OIT0BDj$G$"$k!#%l%9%a%H%j%s$N(Bn-$B%*%/%?%N!<%k(B/$B?eJ,G[78?t$O(B2.9$B!_(B103$B!"%P%$%*%l%9%a%H%j%s$G$O(B6.2$B!_(B104$B$G$"$k!#(B

$B4D6-%5%s%W%k$NJ,@O$*$h$S;DN1J*$NB,Dj$O!"8!=P8B3&(B0.05mg/kg$B$G(BUV$B8!=P4o(B(206nm)$BIU$-$N9bB.1UBN%/%m%^%H%0%i%U$K$h$j $B5$2=$7$?%l%9%a%H%j%s$O!"JaB*:^$H$7$F(BPorpak C 18$B$"$k$$$O(BChromosorb 102$B$N;HMQ$K$h$j!"8zN($h$/2s<}J,@O$G$-$k!#(B



$B%l%9%a%H%j%s(B-4$B

a$B!!J*
$B2=3X<0(BC22H26O3
$B2=3X9=B$(B

(1) $B%P%$%*%l%9%a%H%j%s(B
$B!!!!(B$B#3

(2) $B%7%9%a%H%j%s(B
$B!!!!(B$B#3

(3) (-)-$B%H%i%s%9(B-$B%l%9%a%H%j%s(B
$B!!!!(B$B#3

(4) (-)-$B%7%9(B-$B%l%9%a%H%j%s(B
$B!!!!(B$B#3

$BJ,;RNL(B338.48
$B0lHLL>(BResmethrina
CAS$B2=3XL>(B[5-(phenylmethyl)-3-furanyl]methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
$B$=$NB>$NL>>N$*$h$S>&IJL>(B Benzofuroline, Benzylfuroline, Chrysron, Chryson, Synthrin, For-Syn, NIA 17370, NR DC 104, SB P-1382, ENT 27474, FMC 17370, RU 48440, Pynosect, Pyretherm, Premgard
CAS$BEPO?HV9f(B10453-86-8
RTECS$BHV9f(BGZ1310000b
$BN)BNFC0[E*L>>N(Bc,d5-benzyl-3-furylmethyl[1RS, cis, trans]-2,2-dimethyl-3-(2,2-dimethylvinyl)-cyclopropanecarboxylate$B$^$?$O(B5-benzyl-3-furylmethyl[1RS, cis, trans]-chrysanthemate
$BN)BN0[@-BN9=@.Hf(Be(1)$B!!!!!!(BBioresmethrin
(2)$B!!!!!!(BCismethrin
(3)$B!!!!!!(B(-)-trans-resmethrin
(4)$B!!!!!!(B(-)-cis-resmethrin
(1):(2):(3):(4)=4:1:4:1

  1. ISO$B0lHLL>(B:$B;&Cn:^$*$h$SB>$NG@6HMQ2=3XJ*$O9q:]I8=`2=5!9=(B(ISO)$B$N5;=Q0Q0w2q$K$h$j>5G'$5$l$F$$$k(B
  2. NIOSH(1983)
  3. $B%l%9%a%H%j%s$N;@$NItJ,$N(B(1R)$B!"(Bd$B!"(B(+)$B$^$?$O(B(1S)$B!"(Bl$B!"(B(-)$B$O$=$l$>$lF1$8N)BNFC0[E*G[:B$rI=$9(B
  4. $B5F;@(B(Chrysanthemic acid)$B$O%l%9%a%H%j%s$r9=@.$7$F$$$k;@$NL>>N(B
  5. $B3g8LFb$N?t;z$ON)BN0[@-BN$N2=3X9=B$<0$NHV9f$KAj1~$9$k(B


b$B!!J*M}E*!&2=3XE*FC@-(B
$BI=!!%l%9%a%H%j%s$NJ*M}E*!&2=3XE*FC@-(B
$BJ*M}E*>uBV(B$B$m$&>u8GBN(B
$B?'(B$BL5?'(B
$BHf=E(B(20$B!n(B)1.050
$BJ(E@(B(0.01mmHg)180$B!n(B
$BM;E@(B43$B!A(B48$B!n(B
$B>x5$05(B(30$B!n(B)1.1$B!_(B10-8mmHg
$BMO2r@-!!?e(B(30$B!n(B)<1mg/l
$BM-5!MOG^(B$B%a%?%N!<%k!!(B81g/kg
$B%X%-%5%s!!!!(B220g/kg
$B%-%7%l%s!!!!(B>1kg/kg
$B%1%m%7%s!!!!(B10%
$B1v2=%a%A%l%s$HK'9aB2@PL}C:2=?eAGN`Cf$G$OHs>o$KMO$1$d$9$$(B
n-$B%*%/%?%N!<%k(B/$B?eJ,G[78?t(B2.9$B!_(B103
$B0BDj@-(B$B%"%k%+%jG^BNCf$*$h$S6u5$$^$?$O8w$K$h$j!"5^B.$KJ,2r$9$k(B


(1)$B!!%P%$%*%l%9%a%H%j%s(B
a$B!!J*
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$B!!(B
$BJ,;RNL(B338.48
$B0lHLL>(BBioresmethrina
CAS$B2=3XL>(B[5-(phenylmethyl)-3-furanyl]methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
$B$=$NB>$NL>>N$*$h$S>&IJL>(B d-trans-Resmethrin,(+)-trans-Resmethrin, NR DC 107,RU 11484
CAS$BEPO?HV9f(B28434-01-7
RTECS$BHV9f(BGZ1310500b
$BN)BNFC0[E*L>>N(Bc,d5-benzyl-3-furylmethyl[1R, trans]-chrysanthemate


b$B!!J*M}E*!&2=3XE*FC@-(B
$BI=!!%P%$%*%l%9%a%H%j%s$NJ*M}E*!&2=3XE*FC@-(B
$BJ*M}E*>uBV(B$BG4@-$N$"$kL}>u(B($B1UBN$^$?$O8GBN(B)
$B?'(B$B$[$H$s$IL5?'(B
$BHf=E(B(20$B!n(B)1.050
$BJ(E@(B(0.01mmHg)180$B!n(B
$BM;E@(B30$B!A(B35$B!n(B
$B>x5$05(B(25$B!n(B)1.4$B!_(B10-4mmHg
$BMO2r@-!!?e(B(30$B!n(B)$B!!(B<0.3mg/l
$BM-5!MOG^(B$BMO2r$9$k(B
n-$B%*%/%?%N!<%k(B/$B?eJ,G[78?t(B6.2$B!_(B104


(2)$B!!%7%9%a%H%j%s(B
a$B!!J*
$B2=3X<0(BC22H26O3
$B2=3X9=B$(B $B!!!!(B$B#3

$BJ,;RNL(B338.48
$B0lHLL>!!!!!!(BCismethrina
CAS$B2=3XL>(B [5-(phenylmethyl)-3-furanyl]methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
$B$=$NB>$NL>>N$*$h$S>&IJL>(B(+)-cis-Resmethrin, NR DC 119
CAS$BEPO?HV9f(B35764-59-1
RTECS$BHV9f(BGZ1430000b
$BN)BNFC0[E*L>>N(Bc,d5-benzyl-3-furylmethyl[1R, cis]-chrysanthemate
$BMO2r@-!!M-5!MOG^(B$BMO2r$9$k(B


(3)$B!!(B(-)-$B%H%i%s%9(B-$B%l%9%a%H%j%s(B
a$B!!J*
$B2=3X<0(BC22H26O3
$B2=3X9=B$(B $B!!!!(B$B#3

$BJ,;RNL(B338.48
$B0lHLL>(B(-)-trans-resmethrina
CAS$B2=3XL>(B[5-(phenylmethyl)-3-furanyl]methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
RTECS$BEPO?HV9f(B GZ 1410000b
$BN)BNFC0[E*L>>N(Bc,d5-benzyl-3-furylmethyl[1S,trans]-chrysanthemate


(4)$B!!(B(-)-$B%7%9(B-$B%l%9%a%H%j%s(B
a$B!!J*
$B2=3X<0(BC22H26O3
$B2=3X9=B$(B $B!!!!(B$B#3

$BJ,;RNL(B338.48
$B0lHLL>(B(-)-cis-resmethrina
CAS$B2=3XL>(B[5-(phenylmethyl)-3-furanyl]methyl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate
RTECS$BHV9f(BGZ1420000b
$BN)BNFC0[E*L>>N(Bc,d5-benzyl-3-furylmethyl[1S, cis]-chrysanthemate

  1. ISO$B0lHLL>(B:$B;&Cn:^$*$h$SB>$NG@6HMQ2=3XJ*$O9q:]I8=`2=5!9=(B(ISO)$B$N5;=Q0Q0w2q$K$h$j>5G'$5$l$F$$$k(B
  2. NIOSH(1983)
  3. $B%l%9%a%H%j%s$N;@$NItJ,$N(B(1R)$B!"(Bd$B!"(B(+)$B$^$?$O(B(1S)$B!"(Bl$B!"(B(-)$B$O$=$l$>$lF1$8N)BNFC0[E*G[:B$rI=$9(B
  4. $B5F;@(B(Chrysanthemic acid)$B$O%l%9%a%H%j%s$r9=@.$7$F$$$k;@$NL>>N(B

Elliot(1976); FAO/WHO(1976); Martin & Worthing(1977); Meister et al.(1983); Puchalski(1983); Worthing & Walker(1983); Devaux & Bolla(1986)

1.2$B!!@8;:$HMQES(B

$B%l%9%a%H%j%s$NG/4V$N@8;:NL$H>CHqNL$O!"Ls(B20$B!A(B30$B%H%s$H?dDj$5$l$F$$$k!#%l%9%a%H%j%s$Oe$N:+Cn6n=|$KMQ$$$i$l$k!#$=$l$O!"%(%"%m%>%k!"L}:^!"F}:^$H$7$F@=:^2=$5$l$F$$$k!#$^$?!"B>$N;&Cn:^$*$h$S(B/$B$^$?$OJd=u:^$r4^$`@=:^$bD4@=$5$l$F$$$k!#(B

$B%P%$%*%l%9%a%H%j%s$O!"CyB"9rJ*$KBP$7$F!"$^$?!"29<e$N:+Cn6n=|$KMQ$$$i$l$k!#(B

1.3$B!!?)IJCf$N;DN1J*(B

$BG@:nJ*(B($B%H%^%H!"%l%?%9(B)$B>e$K;6I[$5$l$?%l%9%a%H%j%s$OJ,2r$5$l!"$=$N;DN1$O%H%^%H$G$O(B3$BF|8e$K$OL5;k$7F@$kNL$K!"$^$?!"%l%?%9$G$O(B7$BF|8e$K(B0.1mg/kg$B0J2<$K$J$k!#%P%$%*%l%9%a%H%j%s$OCyB"9rJ*>e$G$+$J$j0BDj$G!"(B4mg/kg$B$N;DN1$O(B6$B%+7n$G(B1.1mg/kg$B$K8:>/$9$k!#;6I[$r.G~J4(B(whole$B!!(Bmeal)($BLu $B;:MqCf$NGr?'%l%0%[%s$N;s7\$KBP$7!"J|cis$B$*$h$S(Btrans-$B0[@-BN$N%l%9%a%H%j%s(B10mg/kg$B$NMQNL$r7P8}EjM?$7$?>l9g!"J|e$,(B24$B;~4V8e$KGS]uJ*Cf$KGS=P$5$l$?!#MqGr$*$h$SMq2+!"BN;iKCCf$N;DN1J*$O>/$J$/!":G9bNL$O4NB!$*$h$S?UB!$KB8:_$7$?!#(B

$Bcis-$B0[@-BN$Otrans-$B0[@-BN$O/$J$/(B(1$B&L(Bg/g$B0J2<(B)$B!"$4$/Dc%l%Y%k$NJ|

1.4$B!!4D6-Cf$N1?L?(B(fate)

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