Research Activities
Study for assessment and implication of genotoxicity
Development of risk assessment strategy of genotoxic carcinogens for food additives
Construction of risk assessment strategy of genotoxicity for flavours as food additives
Study for development of new assays and modification approach of genotoxicity tests
Development and modification of Pig-a assay for gene mutation
Development and modification of in vitro gene mutation assay using hepatocyte
Identification of mutagens derived from food and its screening method using bacteria
Genotoxicity assessment system for nano-materials using Ames test
Development of epi-mutagen detection system using yeast
Basic research for mechanism of genotoxicity
Determination of mechanism of chromosome aberration using a live cell imaging technique
Construction of DNA oligomers including specific DNA adducts at a specific locus
Molecular mechanism of DNA topoisomerase and transcription-coupled nucleotide excision repair
Assessment of genotoxicity for chemicals related to daily life
Assessment of genotoxicity for nano-materials
Assessment of genotoxicity for flavours
Study of structure-activity relationship (SAR) for prediction of genotoxicity for chemicals
Construction of big database for genotoxicity tests
Development of strategy for prediction of genotoxicity using (Q)SAR
Previous works
Development and modification of transgenic rodents gene mutation assays
Study of a new gene mutation assay using whole genome sequencing
Study of gene mutation assay to detect germ cell or heritable mutagenicity