Basic Concept of the 2nd Section

Several Single Nucleotide Polymorphisms (SNPs) in drug metabolizing enzymes and the related regulatory proteins have been identified. SNPs may predispose an individual to a drug-induced adverse event. To promote the appropriate usage of drugs, it is important to identify SNPs that may contribute to the manifestation of adverse events.

Major Research Projects

1. Metabolomic analysis on 12 major disease to find candidates for biomarker and drug target.

2. Biomarker discovery on drug-induced liver injury.

3. Crystal structure of CYP2C9.



Section ChiefF Keiko MAEKAWA, PhD

Research OfficerF Kosuke SAITO, Ph.D.

Research assistantF Yumiko Matsuzawa.

Research assistantF Yoko HASEGAWA.