Websites for Other Drug-Metabolizing Enzymes

 Flavin-Containig Monooxygenases/Dimethylaniline monooxygenase/FMOs (EC 1.14.13.8): IUBMB BRENDA NiceZyme KEGG ERGO

FMO1: EntrezGene GeneCard UniProt
FMO2: EntrezGene GeneCard UniProt
FMO3: EntrezGene GeneCard UniProt
FMO4: EntrezGene GeneCard UniProt
FMO5: EntrezGene GeneCard UniProt

 Flavin-Containig Monoamine Oxidases/Tyraminases/MAOs (EC 1.4.3.4): IUBMB BRENDA NiceZyme KEGG ERGO

Amine Oxidase A/MAOA: EntrezGene GeneCard UniProt
Amine Oxidase B/MAOB: EntrezGene GeneCard UniProt

 Alcohol Dehydrogenases (EC 1.1.1.1): IUBMB BRENDA NiceZyme KEGG ERGO Sequences

ADH1/ADH1A: EntrezGene GeneCard UniProt
ADH2/ADH1B: EntrezGene GeneCard UniProt
ADH3/ADH1C: EntrezGene GeneCard UniProt
ADH4: EntrezGene GeneCard UniProt
ADH5: EntrezGene GeneCard UniProt
ADH6: EntrezGene GeneCard UniProt
ADH7: EntrezGene GeneCard UniProt

 Aldehyde Dehydrogenases (NAD) (EC 1.2.1.3): IUBMB BRENDA NiceZyme KEGG ERGO

ALDH1A1/ALDH1: EntrezGene GeneCard UniProt
ALDH1A2/RALDH2: EntrezGene GeneCard UniProt
ALDH1B1/ALDH5: EntrezGene GeneCard UniProt
ALDH2: EntrezGene GeneCard UniProt
ALDH3A2/ALDH10: EntrezGene GeneCard UniProt
ALDH9A1/ALDH7/ALDH9: EntrezGene GeneCard UniProt

 Aldehyde Dehydrogenases [NAD(P)] (EC 1.2.1.5): IUBMB BRENDA NiceZyme KEGG ERGO

ALDH1A3/ALDH6: EntrezGene GeneCard UniProt
ALDH3A1/ALDH3: EntrezGene GeneCard UniProt
ALDH3B1/ALDH4/ALDH7: EntrezGene GeneCard UniProt
ALDH3B2/ALDH8: EntrezGene GeneCard UniProt

Acyl-CoA Dehydrogenases (EC 1.3.99.3): IUBMB BRENDA NiceZyme KEGG ERGO

Medium-Chain Specific Acyl-CoA Dehydrogenase/MCAD/ACADM: EntrezGene GeneCard UniProt
Long-Chain Specific Acyl-CoA Dehydrogenase/LCAD/ACADL: EntrezGene GeneCard UniProt

Dihydrolipoamide Dehydrogenase/Lipoyl Dehydrogenase (EC 1.8.1.4): IUBMB BRENDA NiceZyme KEGG ERGO

DLD: EntrezGene GeneCard UniProt

Hydroxysteroid Dehydrogenases

HSD3B1/Hydroxy-Delta-5-Steroid Dehydrogenase 1 (EC 1.1.1.145): IUBMB BRENDA NiceZyme KEGG ERGO EntrezGene GeneCard UniProt
HSD3B2/Hydroxy-Delta-5-Steroid Dehydrogenase 2: EntrezGene GeneCard UniProt
HSD11B1/Hydroxysteroid 11b-Dehydrogenase 1(EC 1.1.1.146) : IUBMB BRENDA NiceZyme KEGG ERGO EntrezGene GeneCard UniProt
HSD11B2/Hydroxysteroid 11b-Dehydrogenase 2: EntrezGene GeneCard UniProt
HSD17B1/Hydroxysteroid 17b-Dehydrogenase 1/Estradiol 17b-Dehyrogenase 1 (EC 1.1.1.62) : IUBMB BRENDA NiceZyme KEGG ERGO EntrezGene GeneCard UniProt
HSD17B2/Hydroxysteroid 17b-Dehydrogenase 2/Estradiol 17b-Dehyrogenase 2: EntrezGene GeneCard UniProt
HSD17B3/Hydroxysteroid 17b-Dehydrogenase 3/Estradiol 17b-Dehyrogenase 3: EntrezGene GeneCard UniProt
HSD17BP1 (pseudogene): EntrezGene GeneCard

 Peroxidases (EC 1.11.1.7): IUBMB BRENDA NiceZyme KEGG ERGO

Myeloperoxidase/MPO: EntrezGene GeneCard UniProt

 Glutahione Peroxidases (EC 1.11.1.9): IUBMB BRENDA NiceZyme KEGG ERGO

GPX1: EntrezGene GeneCard UniProt
GPX2: EntrezGene GeneCard UniProt

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 NAD(P)H:Quinone Oxidoreductases (EC 1.6.99.2): IUBMB BRENDA NiceZyme KEGG ERGO

NQO1/DT Diaphorase/Azoreductase: EntrezGene GeneCard UniProt
NQO2: EntrezGene GeneCard UniProt

 Sulfoxide Reductases (EC 1.8.4.5): IUBMB BRENDA NiceZyme KEGG ERGO

Methionine Sulfoxide Reductase A/MRSA : EntrezGene GeneCard

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 Dihydropyrimidine Dehydrogenase (EC 1.3.1.2): IUBMB BRENDA NiceZyme KEGG ERGO

DPYD: EntrezGene GeneCard Uniprot

 Cytidine Deaminase/Cytidine aminohydrolase (EC 3.5.4.5): IUBMB BRENDA NiceZyme KEGG ERGO

CDA: EntrezGene GeneCard Uniprot

 dCMP Deaminase (EC 3.5.4.12): IUBMB BRENDA NiceZyme KEGG ERGO

TCDT: EntrezGene GeneCard Uniprot

 Ribonucleotide-Diphosphate Reductase (EC 1.17.4.1): IUBMB BRENDA NiceZyme KEGG ERGO

M1 subunit (RRM1): EntrezGene GeneCard UniProt
M2 subunit (RRM2): EntrezGene GeneCard UniProt

 Thymidine Phosphorylase/ECGF1 (EC 2.4.2.4): IUBMB BRENDA NiceZyme KEGG ERGO

ECGF1: EntrezGene GeneCard Uniprot

 Uridine Phosphorylases (EC 2.4.2.3): IUBMB BRENDA NiceZyme KEGG ERGO

UPP1: EntrezGene GeneCard Uniprot
UPP2: EntrezGene GeneCard Uniprot

Thymidine Kinase (EC 2.7.1.21): IUBMB BRENDA NiceZyme KEGG ERGO

TK: EntrezGene GeneCard Uniprot

Uridine/Cytidine Kinases (EC 2.7.1.48): IUBMB BRENDA NiceZyme KEGG ERGO

UCK1: EntrezGene GeneCard Uniprot
UCK2: EntrezGene GeneCard Uniprot

 UMP Synthase/Orotate Phosphoribosyl Transferase/Orotidine-5'-Decarboxylase (EC 4.1.1.23): IUBMB BRENDA NiceZyme KEGG ERGO

UMPS/OPRT/ODC: EntrezGene GeneCard Uniprot

 UMP/CMP Kinase (EC 2.7.4.14): IUBMB BRENDA NiceZyme KEGG ERGO

CMPK/UMPK/UMP-CMPK: EntrezGene GeneCard Uniprot

Deoxycytidine Kinase (EC 2.7.1.74): IUBMB BRENDA NiceZyme KEGG ERGO

DCK: EntrezGene GeneCard Uniprot

 dUTP Pyrophosphatase (EC 3.6.1.23): IUBMB BRENDA NiceZyme KEGG ERGO

DUT: EntrezGene GeneCard Uniprot

 5'-Nucleotidases (EC 3.1.3.5): IUBMB BRENDA NiceZyme KEGG ERGO

NT5C1A: EntrezGene GeneCard Uniprot
NT5C1B: EntrezGene GeneCard Uniprot
NT5C2: EntrezGene GeneCard Uniprot
NT5C2L1: EntrezGene
NT5C3: EntrezGene GeneCard Uniprot
NT5E: EntrezGene GeneCard Uniprot

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 5,10-Methylenetetrahydrofolate Reductase (EC 1.5.1.20): IUBMB BRENDA NiceZyme KEGG ERGO

MTHFR: EntrezGene GeneCard Uniprot

 5,10-Methenyltetrahydrofolate Synthase/5-Formyltetrahydrofolate Cyclo-ligase (EC 6.3.3.2): IUBMB BRENDA NiceZyme KEGG ERGO

MTHFS: EntrezGene GeneCard Uniprot

 Serine Hydroxymethyltranseferase/Glycine Hydroxymethyltransferase (EC 2.1.2.1 ): IUBMB BRENDA NiceZyme KEGG ERGO

SHMT1: EntrezGene GeneCard Uniprot
SHMT2: EntrezGene GeneCard Uniprot

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Updated on Nov. 10, 2006
MPJ-6, NIHS, Japan