Detailed Information

SNP ID FP0000576 Gene Symbol ABCB1 Chromosome 7q21.1 Original ID MPJ6_AB1047 rs1186744 Site Intron 27 Reference Sequence NT_007933.14 Position 1 12368209 Position 2 12368106 Position 3 38556 Position 4 IVS27-168 Obserbed T/C 5'-Flanking GTTTCACCGTGT 3'-Flanking AGCCAGGATGGT Effect Frequency 7/1064 Method Sequencing 1st Forward Primer MDR1-6ZF1 CGGCTGGACTTACTCATGTG 1st Reverse Primer MDR1-6ZR1 CACTTTATGCAAACATTTCA 2nd Forward Primer MDR1-28F2 CAAGCCCAGCTAATTTTTTG 2nd Reverse Primer MDR1-28R1 TCTGAACTTGACTGAGGAAA SQ Forward Primer MDR1-28F5 ACTGTGGAGCTTTTTATGGA SQ Reverse Primer MDR1-28R2S GGAAATGTTAAACAGATACC Reference 1 Sai et al., Pharmacogenetics, 13, 741-757, 2003. Reference 2 Sai et al., 2006, Ann. Hum. Genet., 70, 605-622. Haplotype Block 3 *1f Comment 1 Position 2: Reference sequence is NT_007933.10. Position 3: Reference sequence is AC005068.2. Position 4: cDNA-based numbering. Comment 2 C in NT_017168.9. Frequency and haplotype: References 1 and 2. C in NT_007933.14. Release Date 2005/10/25 Update Date 2007/06/12

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SQ=Sequencing; TP=Typing; IVS=Intervening Sequence; CYPalleles, http://www.imm.ki.se/CYPalleles/ .