Angew. Chem. Int. Ed., 2004, 43, 5360-5363
| The Pharmaceutical Society of Japan |
| Chemical Society of Japan |
| American Chemical Society |
| The Synthetic Organic Chemistry, Japan |
| The Japanese Peptide Society |
| Society of Computer Chemistry, Japan |
| The Vitamin Society of Japan |
| The European Peptide Society |
Recent Major Publications
2011
|
Screw-sense control of helical oligopeptides containing equal
amounts of L- and D-amino acids. |
| Design of a stabilized short helical peptide and its application to catalytic
enantioselective epoxidation of (E)-chalcone N. Yamagata, Y. Demizu, Y. Sato, M. Doi, M. Tanaka, K. Nagasawa, H. Oku a, M. Kurihara Tetrahedron Lett., 52, 798-801 (2011) |
| Facile synthesis of stereoisomers of the non-secosteroidal ligand
LG190178 and their evaluation using the mutant vitamin D receptor; Y. Demizu, A. Nakatsu, Y. Sato, S. Honzawa, A. Yamashita, T. Sugiura, A. Kittaka, S. Kato, H. Okuda, M. Kurihara Lett. Org. Chem. 8, 43-47 (2011) |
|
Design, synthesis and X-ray crystallographic
study of new nonsecosteroidal vitamin D receptor ligands. |
|
Conformational studies on peptides containing
α,α-disubstituted α-amino acids: chiral cyclic α,α-disubstituted α-amino acid as
an α-helical inducer |
|
Effect of one D-Leu residue on right-handed
helical -L-Leu-Aib- peptides in the crystal state. |
|
Enantioselective epoxidation of α,β-unsaturated
ketones catalyzed by stapled helical l-Leu-based peptides Original Research Article |
|
Identification of Mutaprodenafil in a Dietary
Supplement and Its Subsequent Synthesis |
| β-PNA: Peptide nucleic acid (PNA) with a chiral center at the β-position
of the PNA backbone T. Sugiyama, Y. Imamura, Y. Demizu, M. Kurihara, M. Takano, A. Kittaka; Bioorg. Med. Chem. Lett., 21, 7317-7320 (2011) |
| Facile synthesis of stereoisomers of the non-secosteroidal ligand LG190178
and their evaluation using the mutant vitamin D receptor; Y. Demizu, A.
Nakatsu, Y. Sato, S. Honzawa, A. Yamashita, T. Sugiura, A. Kittaka, S.
Kato, H. Okuda, M. Kurihara Lett. Org. Chem. 8, 43-47 (2011) |
| Solid-Phase Nucleophilic Fluorination Y. Demizu, K. Sano, N. Terayama, W. Hakamata, Y. Sato, H. Inoue, H. Okuda, M. Kurihara Synth. Commun., in press |
2010
| Three-Dimensional Structural Control of Diastereomeric Leu-Leu-Aib-Leu-Leu-Aib Sequences in the Solid State Demizu, Y., Doi, M., Sato, Y., Tanaka, M., Okuda, H., Kurihara, M J. Org. Chem., 75, 5234-5239 (2010) |
| Stabilized α-helix-catalyzed enantioselective epoxidation of α,β-unsaturated ketones Nagano, M., Doi, M., Kurihara, M., Suemune, H., Tanaka, M. Org. Lett., 12, 3564-3566 (2010) |
| Solid-state conformation of diastereomeric -Pro-Pro-(Aib)4 sequences M. Oba, Y. Demizu,, N. Yamagata, Y. Sato, M. Doi, M. Tanaka, H. Suemune, H. Okuda, M. Kurihara Tetrahedron, 66, 2293–2296 (2010) |
| Controlling the helical screw sense of peptides with C-terminal
L-valine Demizu, Y., Yamagata, N., Sato, Y., Doi, M., Tanaka, M., Okuda, H., Kurihara, M. J. Pept. Sci. 16, 153-158(2010) |
| Conformations of
peptides containing a chiral cyclic α,α-disubstituted
α-amino acid
within the sequence of Aib residues; Demizu, Y., Tanaka, Masakazu, Doi, Mitsunobu, Kurihara, M., Okuda, H., Suemune, H. J. Pept. Sci., 16, 621-626(2010) |
| Conformational analysis of water-soluble oligopeptide composed of chiral
cyclic α,α-disubstituted α-amino acids Y. Demizu, M. Tanaka, H. Suemune, M. Doi, Y. Sato, H. Okuda, M. Kurihara Peptide Science 2009, 381-382(2010) |
| Controlling
the helical screw sense of peptides by N-terminal praline N. Yamagata, Y. Demizu, Y. Sato, M. Oba, M. Tanaka, M. Doi, K. Nagasawa, H. Suemune, H. Okuda, M. Kurihara Peptide Science 2009, 383-384(2010) |
| Computational study on
helical structure of Chiral a,a-Disubstituted oligopeptides M. Kurihara, Y. Sato, N. Yamagata, Y. Demizu, H. Okuda, M. Nagano, M. Doi, M. Tanaka, H. Suemune Peptide Science 2009, 385-386(2010) |
| Sequence-specific cleavage of DNA by peptide nucleic acids conjugated with
metal complexes T. Sugiyama, K. Ninomiya, Y. Imamura, M. Kurihara, M. Takano, A. Kittaka Peptide Science 2009, 425-426(2010) |
| Computational
study on drug design and prediction of bioactivity for regulation of
non-controlled psychotropic substances M. Kurihara Bull. Natl. Inst. Health Sci., 128, 29-33(2010) |
| Isolation and structural elucidation of cyclopentynafil and N-octylnortadalafil found in a dietary supplement T. Hasegawa, K. Takahashi, M. Saijo, T. Ishii, T. Nagata, M. Kurihara, Y. Haishima, Y. Goda, N. Kawahara Chem. Pharm. Bull., 57, 185-189(2009); Cover Picture |
| Helical-Screw Directions of Diastereoisomeric Cyclic a-Amino Acid Oligomers Nagano, M., Tanaka, M., Doi, M., Demizu, Y., Kurihara, M., Suemune, H. Org. Lett., 11, 1135-1137(2009) |
| Design and Screening Strategies for α-Glucosidase Inhibitors Based on Enzymological Information W. Hakamata, M. Kurihara, H. Okuda, T. Nishio, T. Oku Curr. Top. Med. Chem., 9, 3-12 (2009) |
| Design, Synthesis, and Biological Activity of Boronic acid-Based Histone Deacetylase Inhibitors N. Suzuki, T Suzuki, Y. Ota, T. Nakano, M. Kurihara, H. Okuda, T. Yamori, H. Tsumoto, H. Nakagawa, N. Miyata J. Med. Chem., 52,2909-2922(2009) |
| Synthesis of a 1?-C-Methyl Analogue of 25-Hydroxyvitamin D3: Interaction
with a Mutant Vitamin D Receptor Arg274LeuS. Honzawa, N. Takahashi, A.Yamashita,
T. Sugiura, M. Kurihara, M. A. Arai, S. Kato, A. Kittaka Tetrahedron, in press |
| Computational Study on Helical Structure of a,a-Disubstituted Oligopeptides Containing Chiral a-Amino Acids M. Kurihara, Y. Sato, N. Yamagata, H. Okuda, M. Nagano, Y. Demizu, M. Doi, M. Tanaka, H. Suemune Peptide Science 2008, 149-150(2009) |
| Design and synthesis of chiral cyclic a,a-disubstituted amino acid having azido functions and its oligopeptides H. Takazaki, M. Tanaka, N. Kawabe, M. Nagano, M. Doi, M. Kurihara, H. Suemune Peptide Science 2008, 159-160(2009) |
| Cooperative Strand Invasion by Peptide Nucleic Acid Sugiyama, T., Imamura, Y., Kurihara, M., Kittaka, A Peptide Science 2008, 481-282(2009) |
| Helical-screw handedness of peptides composed of diastereoisomeric
cyclic amino acids Nagano, M., Tanaka, M., Doi, M., Kurihara, M., Suemune, H. Peptide 2008, 106-107(2009) |
| Controlling α-helical secondary structure of
oligopeptides and its use as a chiral catalyst Tanaka, M., Nagano, M., Demizu, Y., Doi, M., Kurihara, M., Suemune, H Peptide 2008, 104-105(2009) |
Chem. Pharm. Bull., 57, 185-189(2009)
2008
| (2S,2'R)-Analogue of LG190178 is a major active isomer; W. Hakamata, Y. Sato, H. Okuda, S. Honzawa, N. Saito, S. Kishimoto, A. Yamamoto, T. Sugiura, A. Kittaka, M. Kurihara,*; Bioorg. Med. Chem. Lett., 18, 120-123(2008) |
| The 2α-(3-hydroxypropyl) group as an active motif in vitamin D3 analogues as agonists of the mutant vitamin D receptor (Arg274Leu) ; S. Honzawa, Y. Yamamoto, A. Yamashita, T. Sugiura, M. Kurihara, M. A. Arai, S. Kato, A. Kittaka; Bioorg. Med. Chem., 16, 3002-3024 (2008) |
| Computational Study on Secondary Structure of Oligopeptides Containing α,α-Disubstituted a-Amino Acids; M. Kurihara*, Y. Sato, F. Kaneko, H. Okuda, M. Nagano, Y. Demizu, M. Doi, M. Tanaka, H. Suemune; Peptide Science 2007, 137-138(2008) |
| Structure of the ligand-binding domain of rat VDR in complex with a nonsecosteroidal vitamin D3 analogue YR301; S. Kakuda, K. Okada, H. Eguchi, K. Takenouchi, W. Hakamata, M. Kurihara, M. Takimoto-Kamimura Acta Crystallogr. F , 64, 970-973(2008) |
| Structure Basis for Recognition of High Mannose Type Glycan Transport Lectin VIP36 T. Satoh, N. P. Cowieson, W. Hakamata, H. Ideo, K. Fukushima, M. Kurihara, K. Kato, K. Yamashita, S. Wakatsuki. PF NEWS, 25, 17-22(2008) |
Acta Crystallogr. F , 64, 970-973(2008)
2007
| Structural basis for recognition of high-mannose type glycoproteins by mammalian transport lectin VIP36; T. Satoh, N. Cowieson, W. Hakamata, H. Ideo, K. Fukushima, M. Kurihara, R. Kato, K. Yamashita, S. Wakatsuki; J. Biol. Chem., 282, 28246-28255(2007) |
| Lipase-Catalyzed Kinetic Resolution of Cyclic trans-1,2-Diols Bearing a Diester Moiety: Synthetic Application to Chiral Seven-Membered Ring α,α-Disubstituted a-Amino Acid; M. Tanaka, Y. Demizu, M. Nagano, M. Hama, Y. Yoshida, M. Kurihara, H. Suemune; J. Org. Chem., 72, 7750 -7756 (2007) |
| Controlling 310-Helix and α-Helix of Short Peptides in the Solid State; Y. Demizu, M. Tanaka, M. Nagano, M. Kurihara, M. Doi, T. Maruyama, H. Suemune; Chem. Pharm. Bull., 55, 840-842 (2007) |
| Computational Study on Conformation of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted a-Amino Acids; M. Kurihara, Y. Sato, W. Hakamata, H. Okuda, Y. Demizu, M. Nagano, N. Kawabe, M. Doi, M. Tanaka, H. Suemune; Peptides 2006, 546-547(2007) |
| Side-chain chiral centers of amino acids and helical-screw handedness of their peptides; M. Tanaka, M. Nagano, Y. Demizu, K. Anan, M. Kurihara, M. Doi, H. Suemune; Peptides 2006, 268-269(2007) |
| Secondary Structure of Heteropeptides Using Chiral Cyclic a,a-Disubstituted Amino Acids; Nagano, M., Tanaka, M., Demizu, Y., Kurihara, M., Doi, M., Suemune, H.: Controlling the Helical ; Peptides 2006, 476-477(2007) |
| Recognition of longer duplex DNA by cooperative strand invasion; T. Sugiyama, Y. Imamura, M. Kurihara, A. Kittaka; Nucleic Acids Symp Ser, 51, 269- 270(2007) |
J. Biol. Chem., 282, 28246-28255(2007); 2e6v| Efficient synthesis of carbopeptoid oligomers: insight into mimicry of b-peptide; Y. Suhara, M. Kurihara, A. Kittaka, Y. Ichikawa; Tetrahedron, 62, 8207-8217(2006) |
| N-Linked Oligosaccharide Processing Enzymes as Molecular Targets for Drug Discovery; W. Hakamata, M. Muroi, T. Nishio, T. Oku, A. Takatsuki, H. Osada, K. Fukuhara, H. Okuda, M. Kurihara; J. Appl. Glycosci., 53, 149-154(2006) |
| Design and synthesis of a-glucosidase inhibitor having DNA cleaving activity; Hakamata, W., Yamamoto, E., Muroi, M., Mochizuki, M., Kurihara, M., Okuda, H., Fukuhara, K.; J. Appl. Glycosci., 53, 255-260 (2006). |
| Methyl-introduced A-ring Analogues of 1a,25-Dihydroxyvitamin D3: Synthesis and Biological Evaluation; T. Fujishima, R. Tsutsumi, Y. Negishi, S. Fujii, H. Takayama, A.Kittaka, M. Kurihara; Anticancer Res., 26, 2633-2636 (2006) |
| Sequence-specific recognition of double-stranded DNA by cooperative strand invasion; Sugiyama, T., Imamura, Y., Hakamata, W., Kurihara, M., Kittaka, A. ; Nucleic Acids Symposium Series, 50, 157-158 (2006) |
| Synthesis of Various Chiral Cyclic a,a-Disubstituted Amino Acids and Conformational analysis of their Peptides; N. Kawabe, Y. Demizu, M. Tanaka, M. Kurihara, and H. Suemune; Peptide Science 2005, 346-347 (2006) |
| Chiral Cyclic a,a-Disubstituted a-Amino Acids Bearing Two Chiral Centers and Conformation of Their Peptides; M. Nagano, Y Demizu, M. Tanaka, M. Kurihara, M. Doi, H. Suemune; Peptide Science 2005, 345-346 (2006) |
| Computational Study on Conformation of Oligopeptides Containing Chiral Cyclic α,α-Disubstituted a-Amino Acids; M. Kurihara, Y. Sato, W. Hakamata, H. Okuda, Y. Demizu, M. Nagano, N. Kawabe, M. Doi, M. Tanaka, H. Suemune; Peptide Science 2005, 371-372 (2006) |
| Hama, M., Tanaka, M., Yoshida, Y., Demizu, Y., Kurihara, M., Suemune, H.: Synthesis of optically active cyclic a,a-disubstituted amino acids by enzymatic kinetic resolution and conformational analysis of their peptides.; Peptide Science 2006, 39(2006) |
| Kurihara, M., Sato, Y., Hakamata, W., Okuda, H., Nagano, M., Hama, M., Demizu, Y., Doi, M., Tanaka, M., Suemune, H.: Computational study on helical structures of oligopeptides containing chiral cyclic α,α-disubstituted α-amino acids; Peptide Science 2006, 88(2006) |
| Tanaka, M., Nagano, M., Hama, M., Kawabe, N., Demizu, Y., Kurihara, M., Doi, M., Suemune, H.: Controlling helical secondary structures by cyclic a,a-disubstituted amino acids having side-chain chiral centers; Peptide Science 2006, 135 (2006) |
| Side-chain chiral centers of amino acid and helical screw handedness of its peptides; M. Tanaka, K. Anan, Y. Demizu, M. Kurihara, M. Doi, H. Suemune; J. Am. Chem. Soc., 127,11570-11571(2005) |
| Design, Synthesis and Biological Evaluation of Novel 1α,25-Dihydroxyvitamin D3 Analogues Possessing Aromatic Ring on 2α-Position; S. Honzawa, K. Hirasaka, Y. Yamamoto, S, Peleg, T, Fujishima, M. Kurihara, N. Saito, S. Kishimoto, T. Sugiura, K. Waku, H. Takayama, A. Kittaka; Tetrahedron, 61, 11253-11263 (2005) |
| Cooperative Strand Invasion of Double-Stranded DNA by Peptide Nucleic Acid; T. Sugiyama, Y. Imamura, W. Hakamata, M. Kurihara, A. Kittaka; Nucleic Acids Symposium Series, 49, 167-168 (2005) |
| Computational Study on Conformation of Oligopeptides Controlled by Side Chain Chiralities of α-Amino Acids; M. Kurihara, Y. Sato, W. Hakamata, H. Okuda, Y. Demizu, K. Anan, Y. Takano, M. Oba, M. Doi, M. Tanaka, H. Suemune; Peptide Science 2004, 297-298 (2005) |
| Relationship between a-Amino Acid Chiral Center and Helical Secondary Structure of Its Oligopeptides; M. Tanaka, Y. Demizu, K. Anan, N. Kawabe, Y. Takano, M. Oba, T. Maruyama, M. Doi, M. Kurihara, and H. Suemune; Peptide Science 2004, 45-46 (2005) |
| Prediction of Helical Screw Sense of Oligopeptides Containing Chiral alpha,alpha-Disubstituted alpha-Amino Acids: Computational Study; M. Kurihara, H. Okuda, M. Oba, Y. Demizu, M. Tanaka, H. Suemune; Peptides 2004, 206-207 (2005) |
| Design and Synthesis of Chiral Cyclic alpha,alpha-Disubstituted alpha-Amino Acids and Its Peptides; Y. Demizu, M. Tanaka, K. Anan, Y. Yoshida, M. Doi, M. Kurihara, T. Maruyama, H. Suemune; Peptides 2004, 1027-1028 (2005) |
| Controlling the Helical Screw Sense of Oligopeptide by alpha-Amino Acid Side-chain Chirality; M. Tanaka, Y. Demizu, M. Doi, M. Kurihara H. Suemune; Peptides 2004, 277-278 (2005) |
| Design and Synthesis of Cyclic Urea Compounds: A Pharmacological Study for Retinoidal Activity; M. Kurihara, A. S. S. Rouf, H. Kansui, H. Kagechika H. Okuda, N. Miyata; Bioorg. Med. Chem. Lett., 14, 4131-4134 (2004) |
| a-Amino Acid Side-Chain Chiral Centres Control the Helical Screw Sense of Peptides without a Chiral Centre at the a-Carbon; M. Tanaka, Y. Demizu, M. Doi, M. Kurihara, H. Suemune; Angew. Chem. Int. Ed., 2004, 43, 5360-5363; Cover Picture |
| Design and Efficient Synthesis of 2a-(w-Hydroxyalkoxy)-1a,25-dihydroxyvitamin D3 Analogues, Including 2-epi-ED-71 and Their 20-Epimers with HL-60 Cell Differentiation Activity; N. Saito, Y. Suhara, M. Kurihara, T. Fujishima, S. Honzawa, H. Takayanagi, T. Kozono, M. Matsumoto, M. Ohmori, N. Miyata, H. Takayama, A. Kittaka; J. Org. Chem., 2004, 69, 7463-7471 |
| Synthesis of C60 derivative for photoaffinity labeling; E. Okada, Y. Komazawa, M. Kurihara, H. Inoue, N. Miyata, H. Okuda, T. Tsuchiya, Y. Yamakoshi; Tetrahedron Lett., 45, 527-529 (2004) |
| 2, 2-Functionlized Analogues of 1a, 25-Dihydroxyvitamin D3, The Potent Inducers of Cell Differentiation ; T. Fujishima, A. Kittaka, M. Kurihara, N. Saito, S. Honzawa, S. Kishimoto, T. Sugiura, K.Waku, H. Takayama; J. Steroid Biochem. Mol. Biol. 89-90, 89-92 (2004) |
| Prediction of helical screw sense of oligopeptides containing chiral amino acids: computational study; M. Kurihara, Y. Sato, S. Nomoto, H. Okuda, M. Oba, Y. Demizu, M. Tanaka, H. Suemune; Peptide Science 2003, 411-412 (2004) |
| Controlling the helical screw sense of oligopeptides by chiral cyclic a,a-disubstituted a-amino acid; M. Tanaka, Y. Demizu, M. Doi, M. Kurihara, H. Suemune; Peptide Science 2003, 109-110 (2004) |
| Controlling the secondary structure of Aib peptides by N-terminal proline; M. Oba, M. Tanaka, H. Suemune, Y. Sato, M. Kurihara; Peptide Science 2003, 397-388 (2004) |
Angew. Chem. Int. Ed., 2004, 43, 5360-5363
| Convenient Preparation of Cyclic Acetals Using Diols, TMS-source and a Catalytic Amount of TMSOTf; M. Kurihara, W. Hakamata ; J. Org. Chem., 68, 3414-3415(2003) |
| An Extended Planar C5 Conformation and a 310-Helical Structure of Peptide-Foldamer Constituted of Diverse alpha-Ethylated alph,alph-Disubstituted alph-Amino Acids; M. Tanaka, S. Nishimura, M. Oba, Y. Demizu, M. Kurihara, H. Suemune; Chemistry Eur. J., 9, 3082-3090 (2003) |
| 2alpha-(3-Hydroxypropyl)- and 2alpha-(3-Hydroxypropoxy)-1a,25-vitamin D3 Accessible to Vitamin D Receptor Mutant Related to Hereditary Vitamin D-Resistant Rickets; A. Kittaka, M. Kurihara, S. Peleg, Y. Suhara, H. Takayama; Chem. Pharm.Bull., 51, 357-358 (2003) |
| Concise Synthesis and Biological Activities of 2a-Alkyl- and 2a-(w-Hydroxyalkyl)-20-epi-1a,25-dihydroxyvitamin D3; S. Honzawa, Y. Suhara, K. Nihei, N. Saito, S. Kishimoto, T. Fujishima, M. Kurihara, T. Sugiura, K. Waku, H. Takayama, A. Kittaka.; Bioorg. Med. Chem. Lett., 13, 3503-3506 (2003) |
| 2, 2-Functionlized Analogues of 1a, 25-Dihydroxyvitamin D3, The Potent Inducers of Cell Differentiation; T. Fujishima, A. Kittaka, M. Kurihara, N. Saito, S. Honzawa, S. Kishimoto, T. Sugiura, K.Waku, H. Takayama; J. Steroid Biochem. Mol. Biol. 18, S295 (2002) |
| Computational Study on Conformation of Oligopeptides Containing Chiral alpha, alpha-Disubstituted Amino Acids; M. Kurihara, M. Tanaka, M. Oba, H. Suemune; Peptides 2002, 786-787(2003) |
| Conformational Study of Heteropeptide Prepared from Chiral alpha-Ethylated aipha, alpha-Disubstituted alpha-Amino Acids; M. Tanaka, S. Nishimura, M. Oba, Y. Demizu, M. Kurihara, and H. Suemune; Peptides 2002, 902-903(2003) |
| Conformational Study of Peptides Containing (S)-Ethylleucine as a Chiral alpha,alpha-Disubstituted Amino Acid; M. Oba, M. Tanaka, M. Kurihara, H. Suemune; Peptides 2002, 242-243(2003) |
| Synthesis of Chiral Cyclic a,a-Disubstituted a-Amino Acid and Its Peptides; Y. Demizu, M. Tanaka, M. Kurihara, H. Suemune; Peptide Science 2002 |
| Prediction of the helical screw sense of oligopeptides containing chiral alpha, alpha-disubstituted amino acids; M. Kurihara, Y. Sato, M. Tanaka, M. Oba, Y. Demizu, H. Suemune, H. Okuda; Peptide Science 2002, 323-324(2003) |
| Conformation of Peptides Containing a Chiral a-Ethylated a,a-Disubstituted a-Amino Acid: (S)-EthylLeucine (= (2S)-2-Amino-2-ethyl-4-methylpentanoic Acid) within Sequences of Dimethylglycine and Diethylglycine Residues; M. Oba, M. Tanaka, M. Kurihara, H. Suemune; Helv. Chim. Acta., 85, 3197-3218 (2002) |
| Design and Efficient Synthesis of New Stable 1a,25-Dihydroxy-19-norvitamin D3 Analogues Containing Amide Bond; Y. Suhara, A. Kittaka, K. Ono, M. Kurihara, T. Fujishima, A. Yoshida, H. Takayama; Bioorg. Med. Chem. Lett.12, 3533-3536 (2002) |
| Increasing the conformational stability by replacement of heme axial ligand in c-type cytochrome; T. Satoh, A. Itoga, Y. Isogai, M. Kurihara, S. Yamada, M. Natori, N. Suzuki, K. Suruga, R. Kawachi, M. Arahira, T. Nishio, C. Fukazawa, T. Oku; FEBS letters, 531, 543-547(2002) |
| Conformation of Oligopeptides Containing Chiral a,_a-Disubstituted Amino Acids: Computational Study; M. Kurihara, M. Tanaka, M. Oba, H. Suemune, N. Miyata; Peptide Science 2001, 287-288 (2002) |
| Asymmetric Synthesis and Conformational Analysis of alpha, alpha-Disubstituted alpha-Amino Acids and Their Peptides; M. Tanaka, M. Oba, M. Kurihara, Y. Demizu, S. Nishimura, K. Hayashida, H. Suemune; Peptide Science 2001, 263-266 (2002) |
| Enantioselective Radical Cross-coupling Reactions of Silyl Enol Ethers Using Chiral Oxovanadium; M. Kurihara, T. Hayashi and N. Miyata; Chem. Lett., 2001, 1324-1325 |
| Photochemical Generation of Nitric Oxide from 6-Nitrobenzo[a]pyrene; K. Fukuhara, M. Kurihara, N. Miyata; J. Am. Chem. Soc., 123, 8662-8666 (2001) |
| Synthesis and Biological Evaluation of 5,6-trans-2-Methyl-1,25-dihydroxyvitamin D3 and their 20-Epimers: Possible Binding Modes of Potent A-Ring Analogues to Vitamin D Receptor; T. Fujishima, K. Konno, K. Nakagawa, M. Tanaka, T. Okano, M. Kurihara, N. Miyata, H. Takayama; Chem. Biol., 8, 1011-1024 (2001) |
| Cnoformational Study of Heteropentapeptides Containing an a-Ethylated a,a-Disubstituted Amino Acids: (S)-Butylethylglycine (= 2-Amino-2-ethylhexanoic Acid) within Dimethylglycine (= 2-Aminoisobutyric Acid) Residues; M. Tanaka, M. Oba, N. Imawaka, Y. Tanaka, M. Kurihara, H. Suemune; Helv. Chim. Acta., 84, 32-46 (2001) |
| Efficient and Systematic Synthesis of Novel 2a-Substituted 1a,25-Dihydroxyvitamin D3 Analogues and Docking Analysis to Vitamin D Receptor; Y. Suhara, K. Nihei, M. Kurihara, A. Kittaka, T. Fujishima, K. Konno, N. Miyata, H. Takayama; J. Org. Chem., 66, 8760-8771 (2001) |
| Superoxide Anion Generation via Electron-Transfer Oxidaition of Catechin Dianion by Molecular Oxygen in an Aprotic Medium; I. Nakanishi, K. Fukuhara, K. Ohkubo, T. Shimada, H. Kansui, M. Kurihara, S. Urano, S. Fukuzumi, and N. Miyata; Chem. Lett., 2001, 1152-1153 |
| Mechanism of Antioxidant Effect of Catechins; K. Kondo, M. Kurihara, K. Fukuhara; Methods in Enzymology, 335, 203-217 (2001) |
| Computational Study on Conformation of Oligopeptides Prepared from a,a-Disubstituted Amino Acids; M. Kurihara, M. Tanaka, M. Oba, H. Suemune, N. Miyata ; Peptides 2000, 427-428 (2001) |
| Conformational Study of Peptides Containing a-Ethylated a,a-Disubstituted Amino Acid: (s)-Buthylethylglycine. ;M. Tanaka, N. Imawaka, M. Oba, M. Kurihara, H. Suemune; Peptides 2000, 441-442 (2001) |
| DNA Sequence Recognition by NFkB p50 Homodimer: Strict and Obscure Recognition Sites in the Binding Sequence; A. Kittaka, H. Takayama, M. Kurihara, C. Horii, H. Tanaka, T. Miyasaka, and J. Inoue; Nucleosides Nucleotides & Nucleic Acids, 2001, 20, 669-672. |
| Antioxidation Mechanism of Catechins: Semiempirical Molecular Orbital Calculation Study; M. Kurihara, K. Kondo, K. Fukuhara, M.Toyoda, N. Miyata; Magnetic Resonance in Medicine, 12, 114-117 (2001) |
| Importance of C-2 hydrogen of catechins in scavenging free radicals; K. Kondo, M. Kurihara, K. Fukuhara, T. Suzuki, N. Miyata, M. Toyoda; Magnetic Resonance in Medicine, 12, 91-94 (2001) |
| Antioxidation Mechanisms of Catechins: A Computational Study; M. Kurihara, K. Kondo, M. Toyoda and N. Miyata; JCPE Journal, 13, 255-262 (2001) |
| Conversion of Procyanidin B type (Catechin Dimer) to A type: Evidence for Abstraction of C-2 Hydrogen in Catechin during Radical Oxidation; K. Kondo, M. Kurihara, K. Fukuhara, T. Tanaka, T. Suzuki, N. Miyata, M. Toyoda; Tetrahedron Lett., 41, 485-488 (2000) |
| A Concise and Efficient Route to 2a-(w-Hydroxyalkoxy)-1a, 25-dihydroxyvitamin D3: Remarkable High Affinity to Vitamin D Receptor; A. Kittaka, Y. Suhara, H. Takayanagi, T. Fujishima, M. Kurihara, H. Takayama; Org. Lett., 2, 2619-2622 (2000) |
| Synthesis, Biological Evaluation, and Conformational Analysis of A-Ring Diastereomers of 2-Methyl-1,25-dihydroxyvitamin D3 and Its 20-Epimers.; K. Konno, T. Fujishima, S. Maki, Z. Liu, D. Miura, M. Chokki, S. Ishizuka, K. Yamaguchi, Y. Kan, M.Kurihara, N. Miyata, C. Smith, H. F. DeLuca, H. Takayama; J. Med. Chem., 43, 4247-4265 (2000) |
| Synthesis, Conformation, and Chemical Properties of New Mini Parallel Double-Stranded Peptides Conjugated with -Phe-Phe- and -Phe-Phe-X- Sequences; S. Kobayashi, H. Kobayashi, T. Yamaguchi, M. Nishida, K. Yamaguchi, M. Kurihara, N. Miyata, A. Tanaka; Chem. Pharm. Bull., 48, 920-934 (2000) |
| Trans-4-hydroxy-2-nonenal, an Aldehydic Lipid Peroxidation Pproduct, Lacks Genotoxicity in lacI Transgenic Mice.; A. Nishikawa, F Furukawa, K. Kasahara, S. Ikezaki, T. Itoh, T. Suzuki, K. Uchida, M. Kurihara, M. Hayashi, N. Miyata, M. Hirose; Cancer Lett., 148, 81-6 (2000) |
| Molecular Mechanics Study on Conformational Analysis of Homooligopeptides Prepared from a,a-Disubstituted Amino Acids.; M. Kurihara, M. Tanaka, N. Imawaka, H. Suemune and N. Miyata; Peptide Science 1999, 329-330 (2000) |
| Conformation of Peptides Pprepared from a-Ethylated a,a-Disubstituted Amino Acids; M. Tanaka, N. Imawaka, M. Kurihara, H. Suemune; Peptide Science 1999, 327-328 (2000) |
| Facile Synthesis of 2a-(Hydroxyalkoxy)-1a,25-Dihydroxyvitaminn D3; A. Kittaka, Y. Suhara, H. Takayanagi, T. Fujishima, M. Kurihara, H. Takayama; Vitamin D Endocrine System: Structural, Biological, Genetic and Clinical Aspects, 2000, 49-52. |
| Efficient Synthesis and Biological Evaluation of Novel 2a-Substituted 1a,25-Dihydroxyvitamin D3 Analogs: Remarkable Potency for Calciumregulating Effect; Y. Suhara, K. Nihei, H. Tanigawa, T. Fujishima, K. Konno, K. Nakagawa, T. Okano, M. Kurihara, H. Takayama; Vitamin D Endocrine System: Structural, Biological, Genetic and Clinical Aspects, 2000, 61-64. |